Evl ELISA Kit for Rat(Rattus norvegicus) | EIAab.comEvl ELISA Kit for Rat(Rattus norvegicus)

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Evl (Gene name),

Ena/VASP-like protein (Protein name ), EVL_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Evl(Rnb6);

Protein name:

Ena/VASP-like protein;

Alternative:

Ena/vasodilator-stimulated phosphoprotein-like;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homotetramer (By similarity). Binds to the SH3 domains of ABL1, LYN and SRC. Also binds to profilin, with preference for isoform IIa of PFN2, and the WW domain of APBB1/FE65. Binds to SEMA6A. Interacts, via the Pro-rich region, with the C-terminal SH3 domain of DNMBP. Interacts with RAPH1. Binds, via the EVH1 domain, the Pro-rich domain of ZYX and of Listeria monocytogenes actA.

Function:

Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. Required to transform actin polymerization into active movement for the propulsive force of Listeria monocytogenes.

Subcellular Location:

Cytoplasm cytoskeleton Cell projection lamellipodium Targeted to the leading edge of lamellipodia and the dital tip of stress fibers through interaction with a number of proteins. In activated T-cells, localizes to the F-actin collar and the distal tip of microspikes.

Protein Attributes:

Sequence length:

393

Sequence:

50:

100:

150:

200:

250:

300:

350:

393:

GLDALDLDRM | KQEILEEVVR | ELHKVKEEII | DAIRQELSGI | STT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.28912

SMR:

O08719

Pfam:

PF08776

KEGG:

rno:79115

Pfam:

PF11643

STRING:

10116.ENSRNOP00000032596

String:

O08719

Uniprot:

O08719

FOR

ELISA Kit for Rat Ena/VASP-like protein

CLIA Kit for Rat Ena/VASP-like protein

Polyclonal Antibody for Rat Ena/VASP-like protein

Monoclonal Antibody for Rat Ena/VASP-like protein

Protein for Rat Ena/VASP-like protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Differential display cloning of a novel rat cDNA (RNB6) that shows high expression in the neonatal brain revealed a member of Ena/VASP family."
Ohta S. , Mineta T. , Kimoto M. , Tabuchi K.
Biochem. Biophys. Res. Commun.237:307-312(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain: Wistar.
tissue: Brain.

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