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Index > Protein center > EVPL(Gene name) > Human
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  • EVPL (Gene name),
  • Envoplakin (Protein name ),  EVPL_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    EVPL;
    Protein name:
    Envoplakin;
    Alternative:
    210 kDa paraneoplastic pemphigus antigen;210 kDa cornified envelope precursor protein;p210;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    May form a homodimer or a heterodimer with PPL.
    Function:
    Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments.
    Subcellular Location:
    Cell junction desmosome Cornified envelope Cytoplasm cytoskeleton Colocalized with DSP at desmosomes and along intermediate filaments.
    Protein Attributes:
    Sequence length:
    2033
    Sequence:
    50:
    MFKGLSKGSQ | GKGSPKGSPA | KGSPKGSPSR | HSRAATQELA | LLISRMQANA | 
    100:
    DQVERDILET | QKRLQQDRLN | SEQSQALQHQ | QETGRSLKEA | EVLLKDLFLD | 
    150:
    VDKARRLKHP | QAEEIEKDIK | QLHERVTQEC | AEYRALYEKM | VLPPDVGPRV | 
    200:
    DWARVLEQKQ | KQVCAGQYGP | GMAELEQQIA | EHNILQKEID | AYGQQLRSLV | 
    250:
    GPDAATIRSQ | YRDLLKAASW | RGQSLGSLYT | HLQGCTRQLS | ALAEQQRRIL | 
    300:
    QQDWSDLMAD | PAGVRREYEH | FKQHELLSQE | QSVNQLEDDG | ERMVELRHPA | 
    350:
    VGPIQAHQEA | LKMEWQNFLN | LCICQETQLQ | HVEDYRRFQE | EADSVSQTLA | 
    400:
    KLNSNLDAKY | SPAPGGPPGA | PTELLQQLEA | EEKRLAVTER | ATGDLQRRSR | 
    450:
    DVAPLPQRRN | PPQQPLHVDS | ICDWDSGEVQ | LLQGERYKLV | DNTDPHAWVV | 
    500:
    QGPGGETKRA | PAACFCIPAP | DPDAVARASR | LASELQALKQ | KLATVQSRLK | 
    550:
    ASAVESLRPS | QQAPSGSDLA | NPQAQKLLTQ | MTRLDGDLGQ | IERQVLAWAR | 
    600:
    APLSRPTPLE | DLEGRIHSHE | GTAQRLQSLG | TEKETAQKEC | EAFLSTRPVG | 
    650:
    PAALQLPVAL | NSVKNKFSDV | QVLCSLYGEK | AKAALDLERQ | IQDADRVIRG | 
    700:
    FEATLVQEAP | IPAEPGALQE | RVSELQRQRR | ELLEQQTCVL | RLHRALKASE | 
    750:
    HACAALQNNF | QEFCQDLPRQ | QRQVRALTDR | YHAVGDQLDL | REKVVQDAAL | 
    800:
    TYQQFKNCKD | NLSSWLEHLP | RSQVRPSDGP | SQIAYKLQAQ | KRLTQEIQSR | 
    850:
    ERDRATASHL | SQALQAALQD | YELQADTYRC | SLEPTLAVSA | PKRPRVAPLQ | 
    900:
    ESIQAQEKNL | AKAYTEVAAA | QQQLLQQLEF | ARKMLEKKEL | SEDIRRTHDA | 
    950:
    KQGSESPAQA | GRESEALKAQ | LEEERKRVAR | VQHELEAQRS | QLLQLRTQRP | 
    1000:
    LERLEEKEVV | EFYRDPQLEG | SLSRVKAQVE | EEGKRRAGLQ | ADLEVAAQKV | 
    1050:
    VQLESKRKTM | QPHLLTKEVT | QVERDPGLDS | QAAQLRIQIQ | QLRGEDAVIS | 
    1100:
    ARLEGLKKEL | LALEKREVDV | KEKVVVKEVV | KVEKNLEMVK | AAQALRLQME | 
    1150:
    EDAARRKQAE | EAVAKLQARI | EDLERAISSV | EPKVIVKEVK | KVEQDPGLLQ | 
    1200:
    ESSRLRSLLE | EERTKNATLA | RELSDLHSKY | SVVEKQRPKV | QLQERVHEIF | 
    1250:
    QVDPETEQEI | TRLKAKLQEM | AGKRSGVEKE | VEKLLPDLEV | LRAQKPTVEY | 
    1300:
    KEVTQEVVRH | ERSPEVLREI | DRLKAQLNEL | VNSHGRSQEQ | LIRLQGERDE | 
    1350:
    WRRERAKVET | KTVSKEVVRH | EKDPVLEKEA | ERLRQEVREA | AQKRRAAEDA | 
    1400:
    VYELQSKRLL | LERRKPEEKV | VVQEVVVTQK | DPKLREEHSR | LSGSLDEEVG | 
    1450:
    RRRQLELEVQ | QLRAGVEEQE | GLLSFQEDRS | KKLAVERELR | QLTLRIQELE | 
    1500:
    KRPPTVQEKI | IMEEVVKLEK | DPDLEKSTEA | LRWDLDQEKT | QVTELNRECK | 
    1550:
    NLQVQIDVLQ | KAKSQEKTIY | KEVIRVQKDR | VLEDERARVW | EMLNRERTAR | 
    1600:
    QAREEEARRL | RERIDRAETL | GRTWSREESE | LQRARDQADQ | ECGRLQQELR | 
    1650:
    ALERQKQQQT | LQLQEESKLL | SQKTESERQK | AAQRGQELSR | LEAAILREKD | 
    1700:
    QIYEKERTLR | DLHAKVSREE | LSQETQTRET | NLSTKISILE | PETGKDMSPY | 
    1750:
    EAYKRGIIDR | GQYLQLQELE | CDWEEVTTSG | PCGEESVLLD | RKSGKQYSIE | 
    1800:
    AALRCRRISK | EEYHLYKDGH | LPISEFALLV | AGETKPSSSL | SIGSIISKSP | 
    1850:
    LASPAPQSTS | FFSPSFSLGL | GDDSFPIAGI | YDTTTDNKCS | IKTAVAKNML | 
    1900:
    DPITGQKLLE | AQAATGGIVD | LLSRERYSVH | KAMERGLIEN | TSTQRLLNAQ | 
    1950:
    KAFTGIEDPV | TKKRLSVGEA | VQKGWMPRES | VLPHLQVQHL | TGGLIDPKRT | 
    2000:
    GRIPIQQALL | SGMISEELAQ | LLQDESSYEK | DLTDPISKER | LSYKEAMGRC | 
    2033:
    RKDPLSGLLL | LPAALEGYRC | YRSASPTVPR | SLR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    UniGene:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Envoplakin
    ELISA Kit for Human Envoplakin
    CLIA Kit for Human Envoplakin
    CLIA Kit for Human Envoplakin
    Polyclonal Antibody for Human Envoplakin
    Polyclonal Antibody for Human Envoplakin
    Monoclonal Antibody for Human Envoplakin
    Monoclonal Antibody for Human Envoplakin
    Protein for Human Envoplakin
    Protein for Human Envoplakin

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin."
      Ruhrberg C. , Hajibagheri M.A.N. , Simon M. , Dooley T.P. , Watt F.M.
      J. Cell Biol.134:715-729(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Keratinocyte.
    2. 2.
      "Envoplakin, a possible candidate gene for focal NEPPK/esophageal cancer (TOC): the integration of genetic and physical maps of the TOC region on 17q25."
      Risk J.M. , Ruhrberg C. , Hennies H.-C. , Mills H.S. , Di Colandrea T. , Evans K.E. , Ellis A. , Watt F.M. , Bishop D.T. , Spurr N.K. , Stevens H.P. , Leigh I.M. , Reis A. , Kelsell D.P. , Field J.K.
      Genomics59:234-242(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-1814
      tissue: Cerebellum.
    4. 5.
      "Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell envelope."
      Marekov L.N. , Steinert P.M.
      J. Biol. Chem.273:17763-17770(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LIPIDATION
    5. 6.
      "Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry."
      Denis N.J. , Vasilescu J. , Lambert J.-P. , Smith J.C. , Figeys D.
      Proteomics7:868-874(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-1467
      tissue: Mammary cancer.
    6. 7.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1799;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
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