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Index > Protein center > EXOC2(Gene name) > Human
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  • EXOC2 (Gene name),
  • Exocyst complex component 2 (Protein name ),  EXOC2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    EXOC2(SEC5;SEC5L1);
    Protein name:
    Exocyst complex component 2;
    Alternative:
    Exocyst complex component Sec5;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with EXOC3L1 (By similarity). Interacts with RALA and GNEFR/DELGEF. Interaction with GNEFR occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP. Interacts with RALB.
    Function:
    Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    924
    Sequence:
    50:
    MSRSRQPPLV | TGISPNEGIP | WTKVTIRGEN | LGTGPTDLIG | LTICGHNCLL | 
    100:
    TAEWMSASKI | VCRVGQAKND | KGDIIVTTKS | GGRGTSTVSF | KLLKPEKIGI | 
    150:
    LDQSAVWVDE | MNYYDMRTDR | NKGIPPLSLR | PANPLGIEIE | KSKFSQKDLE | 
    200:
    MLFHGMSADF | TSENFSAAWY | LIENHSNTSF | EQLKMAVTNL | KRQANKKSEG | 
    250:
    SLAYVKGGLS | TFFEAQDALS | AIHQKLEADG | TEKVEGSMTQ | KLENVLNRAS | 
    300:
    NTADTLFQEV | LGRKDKADST | RNALNVLQRF | KFLFNLPLNI | ERNIQKGDYD | 
    350:
    VVINDYEKAK | SLFGKTEVQV | FKKYYAEVET | RIEALRELLL | DKLLETPSTL | 
    400:
    HDQKRYIRYL | SDLHASGDPA | WQCIGAQHKW | ILQLMHSCKE | GYVKDLKGNP | 
    450:
    GLHSPMLDLD | NDTRPSVLGH | LSQTASLKRG | SSFQSGRDDT | WRYKTPHRVA | 
    500:
    FVEKLTKLVL | SQLPNFWKLW | ISYVNGSLFS | ETAEKSGQIE | RSKNVRQRQN | 
    550:
    DFKKMIQEVM | HSLVKLTRGA | LLPLSIRDGE | AKQYGGWEVK | CELSGQWLAH | 
    600:
    AIQTVRLTHE | SLTALEIPND | LLQTIQDLIL | DLRVRCVMAT | LQHTAEEIKR | 
    650:
    LAEKEDWIVD | NEGLTSLPCQ | FEQCIVCSLQ | SLKGVLECKP | GEASVFQQPK | 
    700:
    TQEEVCQLSI | NIMQVFIYCL | EQLSTKPDAD | IDTTHLSVDV | SSPDLFGSIH | 
    750:
    EDFSLTSEQR | LLIVLSNCCY | LERHTFLNIA | EHFEKHNFQG | IEKITQVSMA | 
    800:
    SLKELDQRLF | ENYIELKADP | IVGSLEPGIY | AGYFDWKDCL | PPTGVRNYLK | 
    850:
    EALVNIIAVH | AEVFTISKEL | VPRVLSKVIE | AVSEELSRLM | QCVSSFSKNG | 
    900:
    ALQARLEICA | LRDTVAVYLT | PESKSSFKQA | LEALPQLSSG | ADKKLLEELL | 
    924:
    NKFKSSMHLQ | LTCFQAASST | MMKT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    MIM:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Exocyst complex component 2
    ELISA Kit for Human Exocyst complex component 2
    ELISA Kit for Human Exocyst complex component 2
    CLIA Kit for Human Exocyst complex component 2
    CLIA Kit for Human Exocyst complex component 2
    CLIA Kit for Human Exocyst complex component 2
    Polyclonal Antibody for Human Exocyst complex component 2
    Polyclonal Antibody for Human Exocyst complex component 2
    Polyclonal Antibody for Human Exocyst complex component 2
    Monoclonal Antibody for Human Exocyst complex component 2
    Monoclonal Antibody for Human Exocyst complex component 2
    Monoclonal Antibody for Human Exocyst complex component 2
    Protein for Human Exocyst complex component 2
    Protein for Human Exocyst complex component 2
    Protein for Human Exocyst complex component 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion."
      Sjoelinder M. , Uhlmann J. , Ponstingl H.
      FEBS Lett.532:211-215(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INTERACTION WITH GNEFR
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Placenta.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lymph node.
    4. 4.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
      tissue: Mammary gland.
    6. 6.
      "Solution structure and dynamics of the small GTPase RalB in its active conformation: significance for effector protein binding."
      Fenwick R.B. , Prasannan S. , Campbell L.J. , Nietlispach D. , Evetts K.A. , Camonis J. , Mott H.R. , Owen D.
      Biochemistry48:2192-2206(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RALB
    7. 7.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-454;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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