Protein name:
    Exocyst complex component 8 ;
    
    Alternative:
    
    Exocyst complex 84 kDa subunit ;
    
    
 
    Organism:
        
        
        
        
        
        
    
        Human  (Homo sapiens).  
    
 
General Annotation
    Sub Unit:
    The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with the GTP-bound forms of RALA and RALB via its PH domain.
    
 
    Function:
    Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Cytoplasm 
      
     
      Cell projection  
      growth cone 
      
    Redistributes to growing neurites and growth cones during cell differentiation (By similarity). Binds lipids with phosphatidylinositol-3,4,5-trisphosphate groups. 
  
    
 
    
    Protein Attributes:
    
    50:
    MAMAMSDSGA |  SRLRRQLESG |  GFEARLYVKQ |  LSQQSDGDRD |  LQEHRQRIQA |  
    
 
    100:
    LAEETAQNLK |  RNVYQNYRQF |  IETAREISYL |  ESEMYQLSHL |  LTEQKSSLES |  
    
 
    150:
    IPLTLLPAAA |  AAGAAAASGG |  EEGVGGAGGR |  DHLRGQAGFF |  STPGGASRDG |  
    
 
    200:
    SGPGEEGKQR |  TLTTLLEKVE |  GCRHLLETPG |  QYLVYNGDLV |  EYDADHMAQL |  
    
 
    250:
    QRVHGFLMND |  CLLVATWLPQ |  RRGMYRYNAL |  YSLDGLAVVN |  VKDNPPMKDM |  
    
 
    300:
    FKLLMFPESR |  IFQAENAKIK |  REWLEVLEDT |  KRALSEKRRR |  EQEEAAAPRG |  
    
 
    350:
    PPQVTSKATN |  PFEDDEEEEP |  AVPEVEEEKV |  DLSMEWIQEL |  PEDLDVCIAQ |  
    
 
    400:
    RDFEGAVDLL |  DKLNHYLEDK |  PSPPPVKELR |  AKVEERVRQL |  TEVLVFELSP |  
    
 
    450:
    DRSLRGGPKA |  TRRAVSQLIR |  LGQCTKACEL |  FLRNRAAAVH |  TAIRQLRIEG |  
    
 
    500:
    ATLLYIHKLC |  HVFFTSLLET |  AREFEIDFAG |  TDSGCYSAFV |  VWARSAMGMF |  
    
 
    550:
    VDAFSKQVFD |  SKESLSTAAE |  CVKVAKEHCQ |  QLGDIGLDLT |  FIIHALLVKD |  
    
 
    600:
    IQGALHSYKE |  IIIEATKHRN |  SEEMWRRMNL |  MTPEALGKLK |  EEMKSCGVSN |  
    
 
    650:
    FEQYTGDDCW |  VNLSYTVVAF |  TKQTMGFLEE |  ALKLYFPELH |  MVLLESLVEI |  
    
 
    700:
    ILVAVQHVDY |  SLRCEQDPEK |  KAFIRQNASF |  LYETVLPVVE |  KRFEEGVGKP |  
    
 
    725:
    AKQLQDLRNA |  SRLIRVNPES |  TTSVV
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Mouse
         
        
        Chicken
         
        
        Bovine
         
        
        Human
         
        
        Rat
         
        
     
    
        ELISA Kit for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        ELISA Kit for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        ELISA Kit for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        ELISA Kit for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        ELISA Kit for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Protein for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Protein for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Protein for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Protein for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
    
        Protein for Human Exocyst complex component 8
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
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    References
    
    
        
            
        
            
                1.
                
                    
                        
                            "Complete sequencing and characterization of 21,243 full-length human cDNAs." 
                        
                        
                            Ota T. 
                        ,
                            
Suzuki Y. 
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                              more...   
                             
                        
                        
                        
                            Nat. Genet.36:40-45(2004)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 
                    
                    
                    tissue :
                    
Tongue .  
             
         
            
        
            
                2.
                
                    
                        
                            "The DNA sequence and biological annotation of human chromosome 1." 
                        
                        
                            Gregory S.G. 
                        ,
                            
Barlow K.F. 
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McLay K.E. 
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Kaul R. 
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                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                3.
                
                    
                        
                        
                            Mural R.J. 
                        ,
                            
Istrail S. 
                        ,
                            
Sutton G.G. 
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Florea L. 
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Mobarry C.M. 
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Lippert R. 
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Walenz B. 
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Shatkay H. 
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Dew I. 
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Flanigan M.J. 
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Bolanos R. 
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                        ,
                            
Hannenhalli S. 
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Turner R. 
                        ,
                        
                        
                            Yooseph S. 
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                              more...   
                             
                        
                        
                            Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
                        
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                4.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 
                    
                    
                    tissue :
                    
Lymph .  
             
         
            
        
            
                5.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for INTERACTION WITH EXOC2; RALA AND RALB 
                    
                    
                 
             
         
            
        
            
                6.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-142;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] 
                    
                    
                    tissue :
                    
Cervix carcinoma .  
             
         
            
        
            
                7.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]