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Index > Protein center > Extl2(Gene name) > Mouse
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  • Extl2 (Gene name),
  • Exostosin-like 2 (Protein name ),  EXTL2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Extl2(Extr2);
    Protein name:
    Exostosin-like 2;
    Alternative:
    Alpha-GalNAcT EXTL2;Alpha-1,4-N-acetylhexosaminyltransferase EXTL2;Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;EXT-related protein 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.
    Subcellular Location:
    Endoplasmic reticulum membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    330
    Sequence:
    50:
    MMRGCHICKL | PGRVMGIRVL | RFSLVVILVL | LLVAGALTNL | LPNIKEDKML | 
    100:
    TLRREIKSPS | KSALDSFTLI | MQTYNRTDLL | LRLLNHYQAV | PSLHKVIVVW | 
    150:
    NNVGEKGPEE | LWNSLGPHPI | PVIFKPQTAN | KMRNRLQVFP | EVETNAVLMV | 
    200:
    DDDTLISAQD | LVFAFSIWQQ | FPDQIIGFVP | RKHVSTSSGI | YSYGGFELQT | 
    250:
    PGPGNGDQYS | MVLIGASFFN | SKYLELFQKQ | PAAVHALIDE | TQNCDDIAMN | 
    300:
    FLVTRHTGKP | SGIFVKPINM | VNLEKETNGY | SGMWHRAEHF | LQRSYCINKL | 
    330:
    VNIYDGMPLK | YSNIMISQFG | FPYANHKSKM | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Exostosin-like 2
    ELISA Kit for Mouse Exostosin-like 2
    CLIA Kit for Mouse Exostosin-like 2
    CLIA Kit for Mouse Exostosin-like 2
    Polyclonal Antibody for Mouse Exostosin-like 2
    Polyclonal Antibody for Mouse Exostosin-like 2
    Monoclonal Antibody for Mouse Exostosin-like 2
    Monoclonal Antibody for Mouse Exostosin-like 2
    Protein for Mouse Exostosin-like 2
    Protein for Mouse Exostosin-like 2

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Characterization and genomic localization of the mouse Extl2 gene."
      Wuyts W. , Van Hul W.
      Cytogenet. Cell Genet.89:185-188(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Embryonic head.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Eye.
      tissue: Mammary gland.
    4. 4.
      "Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis."
      Pedersen L.C. , Dong J. , Taniguchi F. , Kitagawa H. , Krahn J.M. , Pedersen L.G. , Sugahara K. , Negishi M.
      J. Biol. Chem.278:14420-14428(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 38-330 IN COMPLEX WITH SUBSTRATE;METAL-BINDING;DISULFIDE BOND;MUTAGENESIS OF ASN-243; ASP-246 AND ARG-293;CATALYTIC ACTIVITY;ACTIVE SITE;BIOPHYSICOCHEMICAL PROPERTIES;COFACTOR
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