Ezr ELISA Kit for Rat(Rattus norvegicus) | EIAab.comEzr ELISA Kit for Rat(Rattus norvegicus)

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Ezr (Gene name),

Ezrin (Protein name ), EZRI_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ezr(Vil2);

Protein name:

Ezrin;

Alternative:

Villin-2;Cytovillin;p81;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with MCC, MPP5, PLEKHG6, SCYL3/PACE1, SLC9A3R1, SCYL3/PACE1 and TMEM8B. Interacts (when phosphorylated) with FES/FPS (By similarity). Found in a complex with EZR, PODXL and SLC9A3R2. Interacts with PODXL and SLC9A3R2.

Function:

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Subcellular Location:

Apical cell membrane Peripheral membrane protein Cytoplasmic side Cell projection Cell projection microvillus membrane Peripheral membrane protein Cytoplasmic side Cell projection ruffle membrane Peripheral membrane protein Cytoplasmic side Cytoplasm cell cortex Cytoplasm cytoskeleton Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Microvillar peripheral membrane protein (cytoplasmic side) (By similarity). Localizes to cell extensions and peripheral processes of astrocytes. Colocalizes with EZR and SLC9A3R2 at the apical cell membrane of glomerular epithelium cells.

Protein Attributes:

Sequence length:

586

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

586:

DIIHNENMRQ | GRDKYKTLRQ | IRQGNTKQRI | DEFEAM

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P31977

Pfam:

PF00769

KEGG:

rno:54319

SMR:

P31977

UniGene:

Rn.773

Uniprot:

P31977

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ELISA Kit for Rat Ezrin

Cat.:

E1297h

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Packing:

96T

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ELISA Kit for Rat Ezrin

Cat.:

E1297r

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96T

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ELISA Kit for Rat Ezrin

Cat.:

E1297b

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Packing:

96T

ELISA Kit for Rat Ezrin

MSDS:

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ELISA Kit for Rat Ezrin

Cat.:

E1297m

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Packing:

96T

CLIA Kit for Rat Ezrin

Cat.:

U1297m

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MSDS:

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Packing:

96T

CLIA Kit for Rat Ezrin

Cat.:

U1297r

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Rat Ezrin

Cat.:

U1297h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rat Ezrin

MSDS:

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CLIA Kit for Rat Ezrin

Cat.:

U1297b

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Ezrin

Cat.:

P1297Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Ezrin

Cat.:

P1297Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Ezrin

Cat.:

P1297Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Ezrin

Monoclonal Antibody for Rat Ezrin

Protein for Rat Ezrin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Rattus norvegicus ezrin."
Harita Y. , Koike H. , Han G. , Miyauchi N. , Karasawa T. , Suzuki K. , Shimizu F. , Kawachi H.
Submitted (2003-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Wistar.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
3.

Gunn-Moore F.J. , Tait S. , Brophy P.J.
Submitted (2001-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-455
strain: Sprague-Dawley.
4.

"Transcriptional regulation of the ezrin gene during rat intestinal development and epithelial differentiation."
Barila D. , Murgia C. , Nobili F. , Perozzi G.
Biochim. Biophys. Acta1263:133-140(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 427-586;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain: Wistar.
tissue: Intestine.
5.

Lubec G. , Chen W.-Q. , Kang S.U.
Submitted (2007-07) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-35; 101-107; 263-273; 372-379; 428-435 AND 530-542;IDENTIFICATION BY MASS SPECTROMETRY
strain: Sprague-Dawley.
tissue: Brain.
tissue: Hippocampus.
6.

"Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton."
Takeda T. , McQuistan T. , Orlando R.A. , Farquhar M.G.
J. Clin. Invest.108:289-301(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PODXL AND SLC9A3R2;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
7.

"Characterization of the NF2 protein merlin and the ERM protein ezrin in human, rat, and mouse central nervous system."
Groenholm M. , Teesalu T. , Tyynelaa J. , Piltti K. , Boehling T. , Wartiovaara K. , Vaheri A. , Carpen O.
Mol. Cell. Neurosci.28:683-693(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;SUBCELLULAR LOCATION

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