Protein name:
Ezrin ;
Alternative:
Villin-2 ;Cytovillin ;p81 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with MCC, MPP5, PLEKHG6, SCYL3/PACE1, SLC9A3R1, SCYL3/PACE1 and TMEM8B. Interacts (when phosphorylated) with FES/FPS (By similarity). Found in a complex with EZR, PODXL and SLC9A3R2. Interacts with PODXL and SLC9A3R2.
Function:
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Subcellular Location:
Apical cell membrane
Peripheral membrane protein
Cytoplasmic side
Cell projection
Cell projection
microvillus membrane
Peripheral membrane protein
Cytoplasmic side
Cell projection
ruffle membrane
Peripheral membrane protein
Cytoplasmic side
Cytoplasm
cell cortex
Cytoplasm
cytoskeleton
Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Microvillar peripheral membrane protein (cytoplasmic side) (By similarity). Localizes to cell extensions and peripheral processes of astrocytes. Colocalizes with EZR and SLC9A3R2 at the apical cell membrane of glomerular epithelium cells.
Protein Attributes:
50:
MPKPINVRVT | TMDAELEFAI | QPNTTGKQLF | DQVVKTIGLR | EVWYFGLQYV |
100:
DNKGFPTWLK | LDKKVSAQEV | RKENPVQFKF | RAKFYPEDVA | DELIQDITQK |
150:
LFFLQVKEGI | LSDEIYCPPE | TAVLLGSYAV | QAKFGDYNKE | MHKSGYLSSE |
200:
RLIPQRVMDQ | HKLSRDQWED | RIQVWHAEHR | GMLKDSAMLE | YLKIAQDLEM |
250:
YGINYFEIKN | KKGTDLWLGV | DALGLNIYEK | DDKLTPKIGF | PWSEIRNISF |
300:
NDKKFVIKPI | DKKAPDFVFY | APRLRINKRI | LQLCMGNHEL | YMRRRKPDTI |
350:
EVQQMKAQAR | EEKHQKQLER | QQLETEKKRR | ETVEREKEQM | LREKEELMLR |
400:
LQDFEQKTKR | AEKELSEQIE | KALQLEEERR | RAQEEAERLE | ADRMAALRAK |
450:
EELERQAQDQ | IKSQEQLAAE | LAEYTAKIAL | LEEARRRKED | EVEEWQHRAK |
500:
EAQDDLVKTK | EELHLVMTAP | PPPPPPVYEP | VNYHVQEGLQ | DEGAEPMGYS |
550:
AELSSEGILD | DRNEEKRITE | AEKNERVQRQ | LLTLSNELSQ | ARDENKRTHN |
586:
DIIHNENMRQ | GRDKYKTLRQ | IRQGNTKQRI | DEFEAM
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Rabbit
Mouse
Polyclonal Antibody for Rat Ezrin
Polyclonal Antibody for Rat Ezrin
Polyclonal Antibody for Rat Ezrin
Polyclonal Antibody for Rat Ezrin
Polyclonal Antibody for Rat Ezrin
Monoclonal Antibody for Rat Ezrin
Monoclonal Antibody for Rat Ezrin
Monoclonal Antibody for Rat Ezrin
Monoclonal Antibody for Rat Ezrin
Monoclonal Antibody for Rat Ezrin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Wistar .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Lung .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-455
strain :
Sprague-Dawley .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 427-586;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain :
Wistar .
tissue :
Intestine .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 28-35; 101-107; 263-273; 372-379; 428-435 AND 530-542;IDENTIFICATION BY MASS SPECTROMETRY
strain :
Sprague-Dawley .
tissue :
Brain .
tissue :
Hippocampus .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PODXL AND SLC9A3R2;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;SUBCELLULAR LOCATION