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Index > Protein center > FAM125B(Gene name) > Human
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  • FAM125B (Gene name),
  • Multivesicular body subunit 12B (Protein name ),  F125B_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    FAM125B(C9orf28);
    Protein name:
    Multivesicular body subunit 12B;
    Alternative:
    Protein FAM125B;ESCRT-I complex subunit MVB12B;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of the ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, a VPS37 protein (VPS37A to -D) and a FAM125/MVB12 protein (FAM125A or -B) in a 1:1:1:1 stoechiometry. Interacts with TSG101; the association appears to be mediated by the TSG101-VPS37 binary subcomplex. Interacts with VPS28. Interacts with VPS37B; the association appears to be mediated by the TSG101-VPS37 binary subcomplex. Interacts with VPS37C; the association appears to be mediated by the TSG101-VPS37 binary subcomplex.
    Function:
    Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.
    Subcellular Location:
    Endosome Late endosome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    319
    Sequence:
    50:
    MRSCFCVRRS | RDPPPPQPPP | PPPQRGTDQS | TMPEVKDLSE | ALPETSMDPI | 
    100:
    TGVGVVASRN | RAPTGYDVVA | QTADGVDADL | WKDGLFKSKV | TRYLCFTRSF | 
    150:
    SKENSHLGNV | LVDMKLIDIK | DTLPVGFIPI | QETVDTQEVA | FRKKRLCIKF | 
    200:
    IPRDSTEAAI | CDIRIMGRTK | QAPPQYTFIG | ELNSMGIWYR | MGRVPRNHDS | 
    250:
    SQPTTPSQSS | AASTPAPNLP | RHISLTLPAT | FRGRNSTRTD | YEYQHSNLYA | 
    300:
    ISAMDGVPFM | ISEKFSCVPE | SMQPFDLLGI | TIKSLAEIEK | EYEYSFRTEQ | 
    319:
    SAAARLPPSP | TRCQQIPQS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Multivesicular body subunit 12B
    ELISA Kit for Human Multivesicular body subunit 12B
    CLIA Kit for Human Multivesicular body subunit 12B
    CLIA Kit for Human Multivesicular body subunit 12B
    Polyclonal Antibody for Human Multivesicular body subunit 12B
    Polyclonal Antibody for Human Multivesicular body subunit 12B
    Monoclonal Antibody for Human Multivesicular body subunit 12B
    Monoclonal Antibody for Human Multivesicular body subunit 12B
    Protein for Human Multivesicular body subunit 12B
    Protein for Human Multivesicular body subunit 12B

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    Linearity
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