Protein name:
Coagulation factor VIII;
Alternative:
Procoagulant component;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with vWF. vWF binding is essential for the stabilization of F8 in circulation.
Function:
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
Subcellular Location:
Secreted
extracellular space
Protein Attributes:
50:
MQIALFACFF | LSLFNFCSSA | IRRYYLGAVE | LSWNYIQSDL | LSVLHTDSRF |
100:
LPRMSTSFPF | NTSIMYKKTV | FVEYKDQLFN | IAKPRPPWMG | LLGPTIWTEV |
150:
HDTVVITLKN | MASHPVSLHA | VGVSYWKASE | GDEYEDQTSQ | MEKEDDKVFP |
200:
GESHTYVWQV | LKENGPMASD | PPCLTYSYMS | HVDLVKDLNS | GLIGALLVCK |
250:
EGSLSKERTQ | MLYQFVLLFA | VFDEGKSWHS | ETNDSYTQSM | DSASARDWPK |
300:
MHTVNGYVNR | SLPGLIGCHR | KSVYWHVIGM | GTTPEIHSIF | LEGHTFFVRN |
350:
HRQASLEISP | ITFLTAQTLL | IDLGQFLLFC | HISSHKHDGM | EAYVKVDSCP |
400:
EESQWQKKNN | NEEMEDYDDD | LYSEMDMFTL | DYDSSPFIQI | RSVAKKYPKT |
450:
WIHYISAEEE | DWDYAPSVPT | SDNGSYKSQY | LSNGPHRIGR | KYKKVRFIAY |
500:
TDETFKTRET | IQHESGLLGP | LLYGEVGDTL | LIIFKNQASR | PYNIYPHGIT |
550:
DVSPLHARRL | PRGIKHVKDL | PIHPGEIFKY | KWTVTVEDGP | TKSDPRCLTR |
600:
YYSSFINPER | DLASGLIGPL | LICYKESVDQ | RGNQMMSDKR | NVILFSIFDE |
650:
NQSWYITENM | QRFLPNAAKT | QPQDPGFQAS | NIMHSINGYV | FDSLELTVCL |
700:
HEVAYWHILS | VGAQTDFLSI | FFSGYTFKHK | MVYEDTLTLF | PFSGETVFMS |
750:
MENPGLWVLG | CHNSDFRKRG | MTALLKVSSC | DKSTSDYYEE | IYEDIPTQLV |
800:
NENNVIDPRS | FFQNTNHPNT | RKKKFKDSTI | PKNDMEKIEP | QFEEIAEMLK |
850:
VQSVSVSDML | MLLGQSHPTP | HGLFLSDGQE | AIYEAIHDDH | SPNAIDSNEG |
900:
PSKVTQLRPE | SHHSEKIVFT | PQPGLQLRSN | KSLETTIEVK | WKKLGLQVSS |
950:
LPSNLMTTTI | LSDNLKATFE | KTDSSGFPDM | PVHSSSKLST | TAFGKKAYSL |
1000:
VGSHVPLNVS | EENSDSNILD | STLMYSQESL | PRDNILSMEN | DRLLREKRFH |
1050:
GIALLTKDNT | LFKDNVSLMK | TNKTYNHSTT | NEKLHTESPT | SIENSTTDLQ |
1100:
DAILKVNSEI | QEVTALIHDG | TLLGKNSTYL | RLNHMLNRTT | STKNKDIFHR |
1150:
KDEDPIPQDE | ENTIMPFSKM | LFLSESSNWF | KKTNGNNSLN | SEQEHSPKQL |
1200:
VYLMFKKYVK | NQSFLSEKNK | VTVEQDGFTK | NIGLKDMAFP | HNMSIFLTTL |
1250:
SNVHENGRHN | QEKNIQEEIE | KEALIEEKVV | LPQVHEATGS | KNFLKDILIL |
1300:
GTRQNISLYE | VHVPVLQNIT | SINNSTNTVQ | IHMEHFFKRR | KDKETNSEGL |
1350:
VNKTREMVKN | YPSQKNITTQ | RSKRALGQFR | LSTQWLKTIN | CSTQCIIKQI |
1400:
DHSKEMKKFI | TKSSLSDSSV | IKSTTQTNSS | DSHIVKTSAF | PPIDLKRSPF |
1450:
QNKFSHVQAS | SYIYDFKTKS | SRIQESNNFL | KETKINNPSL | AILPWNMFID |
1500:
QGKFTSPGKS | NTNSVTYKKR | ENIIFLKPTL | PEESGKIELL | PQVSIQEEEI |
1550:
LPTETSHGSP | GHLNLMKEVF | LQKIQGPTKW | NKAKRHGESI | KGKTESSKNT |
1600:
RSKLLNHHAW | DYHYAAQIPK | DMWKSKEKSP | EIISIKQEDT | ILSLRPHGNS |
1650:
HSIGANEKQN | WPQRETTWVK | QGQTQRTCSQ | IPPVLKRHQR | ELSAFQSEQE |
1700:
ATDYDDAITI | ETIEDFDIYS | EDIKQGPRSF | QQKTRHYFIA | AVERLWDYGM |
1750:
STSHVLRNRY | QSDNVPQFKK | VVFQEFTDGS | FSQPLYRGEL | NEHLGLLGPY |
1800:
IRAEVEDNIM | VTFKNQASRP | YSFYSSLISY | KEDQRGEEPR | RNFVKPNETK |
1850:
IYFWKVQHHM | APTEDEFDCK | AWAYFSDVDL | ERDMHSGLIG | PLLICHANTL |
1900:
NPAHGRQVSV | QEFALLFTIF | DETKSWYFTE | NVKRNCKTPC | NFQMEDPTLK |
1950:
ENYRFHAING | YVMDTLPGLV | MAQDQRIRWY | LLSMGNNENI | QSIHFSGHVF |
2000:
TVRKKEEYKM | AVYNLYPGVF | ETLEMIPSRA | GIWRVECLIG | EHLQAGMSTL |
2050:
FLVYSKQCQI | PLGMASGSIR | DFQITASGHY | GQWAPNLARL | HYSGSINAWS |
2100:
TKEPFSWIKV | DLLAPMIVHG | IKTQGARQKF | SSLYISQFII | MYSLDGKKWL |
2150:
SYQGNSTGTL | MVFFGNVDSS | GIKHNSFNPP | IIARYIRLHP | THSSIRSTLR |
2200:
MELMGCDLNS | CSIPLGMESK | VISDTQITAS | SYFTNMFATW | SPSQARLHLQ |
2250:
GRTNAWRPQV | NDPKQWLQVD | LQKTMKVTGI | ITQGVKSLFT | SMFVKEFLIS |
2300:
SSQDGHHWTQ | ILYNGKVKVF | QGNQDSSTPM | MNSLDPPLLT | RYLRIHPQIW |
2319:
EHQIALRLEI | LGCEAQQQY
Vaild Sequence:
Related Databases
Uniprot:
FOR
ELISA Kit for Mouse Coagulation factor VIII
ELISA Kit for Mouse Coagulation factor VIII
ELISA Kit for Mouse Coagulation factor VIII
ELISA Kit for Mouse Coagulation factor VIII
CLIA Kit for Mouse Coagulation factor VIII
CLIA Kit for Mouse Coagulation factor VIII
CLIA Kit for Mouse Coagulation factor VIII
CLIA Kit for Mouse Coagulation factor VIII
Polyclonal Antibody for Mouse Coagulation factor VIII
Polyclonal Antibody for Mouse Coagulation factor VIII
Polyclonal Antibody for Mouse Coagulation factor VIII
Polyclonal Antibody for Mouse Coagulation factor VIII
Monoclonal Antibody for Mouse Coagulation factor VIII
Monoclonal Antibody for Mouse Coagulation factor VIII
Monoclonal Antibody for Mouse Coagulation factor VIII
Monoclonal Antibody for Mouse Coagulation factor VIII
Protein for Mouse Coagulation factor VIII
Protein for Mouse Coagulation factor VIII
Protein for Mouse Coagulation factor VIII
Protein for Mouse Coagulation factor VIII
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain:
C57BL/6 X CBA.
tissue:
Liver.
-
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
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Hillier L.W.
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Zody M.C.
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Goldstein S.
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She X.
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Bult C.J.
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Teague B.
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Potamousis K.
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Churas C.
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Place M.
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Herschleb J.
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Runnheim R.
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Forrest D.
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Amos-Landgraf J.
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more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed]
[
Europe PMC]
[
Abstract]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain:
C57BL/6J.
-
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]