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Index > Protein center > FABP6(Gene name) > Human
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  • FABP6 (Gene name),
  • Gastrotropin (Protein name ),  FABP6_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FABP6(ILBP;ILLBP);
    Protein name:
    Gastrotropin(GT);
    Alternative:
    Ileal lipid-binding protein(ILBP);Fatty acid-binding protein 6;Intestinal bile acid-binding protein(I-BABP);Intestinal 15 kDa protein(I-15P);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
    Subcellular Location:
    Isoform 2 Cytoplasm Localized close to nucleus on the apical side of both normal and neoplastic cells.
    Protein Attributes:
    Sequence length:
    128
    Sequence:
    50:
    MAFTGKFEME | SEKNYDEFMK | LLGISSDVIE | KARNFKIVTE | VQQDGQDFTW | 
    100:
    SQHYSGGHTM | TNKFTVGKES | NIQTMGGKTF | KATVQMEGGK | LVVNFPNYHQ | 
    128:
    TSEIVGDKLV | EVSTIGGVTY | ERVSKRLA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human GT
    Cat.:
    E2247h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human GT
    Cat.:
    E2247m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human GT
    Cat.:
    E2247r
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    MSDS:
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    96T
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    ELISA Kit for Human GT
    Cat.:
    E2247p
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human GT
    Cat.:
    E2247b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human GT
    MSDS:
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    CLIA Kit for Human GT
    Cat.:
    U2247h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human GT
    Cat.:
    U2247r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human GT
    Cat.:
    U2247b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human GT
    Cat.:
    U2247p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human GT
    Cat.:
    U2247m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human GT
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Human GT
    Polyclonal Antibody for Human GT
    Cat.:
    P2247Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human GT
    Polyclonal Antibody for Human GT
    Cat.:
    P2247Rb-h
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    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human GT
    Cat.:
    P2247Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human GT
    Monoclonal Antibody for Human GT
    Monoclonal Antibody for Human GT
    Monoclonal Antibody for Human GT
    Monoclonal Antibody for Human GT
    Monoclonal Antibody for Human GT
    Monoclonal Antibody for Human GT
    Protein for Human GT
    Protein for Human GT
    Protein for Human GT
    Protein for Human GT
    Protein for Human GT
    Protein for Human GT

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    References
    1. 1.
      "Cloning and chromosomal localization of the human ileal lipid-binding protein."
      Oelkers P. , Dawson P.A.
      Biochim. Biophys. Acta1257:199-202(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Ileum.
    2. 2.
      "Molecular cloning, expression, and characterization of a human intestinal 15-kDa protein."
      Fujita M. , Fujii H. , Kanda T. , Sato E. , Hatakeyama K. , Ono T.
      Eur. J. Biochem.233:406-413(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Ileum.
    3. 3.
      "A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma."
      Fang C. , Dean J. , Smith J.W.
      Cancer Res.67:9039-9046(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;ALTERNATIVE PROMOTER USAGE;INDUCTION;TISSUE SPECIFICITY
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANTS HIS-33 AND TYR-55
      tissue: Brain.
    5. 6.
      "The human ileal bile acid binding protein gene: promoter sequence and effects of CDX2 on expression."
      Barley N.F. , Shaw-Smith C.J. , Chakravarty P. , Howard A. , Legon S. , Walters J.R.
      Submitted (1999-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-19 (ISOFORM 1)
    6. 7.
      "Insights into the bile acid transportation system: the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures."
      Kurz M. , Brachvogel V. , Matter H. , Stengelin S. , Thuering H. , Kramer W.
      Proteins50:312-328(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR IN COMPLEX WITH BILE ACID
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