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Index > Protein center > Fabp2(Gene name) > Rat
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  • Fabp2 (Gene name),
  • Fatty acid-binding protein, intestinal (Protein name ),  FABPI_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (1)
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  • Gene name:
    Fabp2(Fabpi);
    Protein name:
    Fatty acid-binding protein, intestinal;
    Alternative:
    Intestinal-type fatty acid-binding protein(I-FABP);Fatty acid-binding protein 2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    132
    Sequence:
    50:
    MAFDGTWKVD | RNENYEKFME | KMGINVVKRK | LGAHDNLKLT | ITQEGNKFTV | 
    100:
    KESSNFRNID | VVFELGVDFA | YSLADGTELT | GTWTMEGNKL | VGKFKRVDNG | 
    132:
    KELIAVREIS | GNELIQTYTY | EGVEAKRIFK | KE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Fatty acid-binding protein, intestinal
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    E0559h
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    ELISA Kit for Rat Fatty acid-binding protein, intestinal
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    E0559m
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    ELISA Kit for Rat Fatty acid-binding protein, intestinal
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    E0559p
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    ELISA Kit for Rat Fatty acid-binding protein, intestinal
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    E0559b
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    96T
    ELISA Kit for Rat Fatty acid-binding protein, intestinal
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    E0559r
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    96T
    CLIA Kit for Rat Fatty acid-binding protein, intestinal
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    U0559b
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    96T
    CLIA Kit for Rat Fatty acid-binding protein, intestinal
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    U0559m
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    MSDS:
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    96T
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    CLIA Kit for Rat Fatty acid-binding protein, intestinal
    Cat.:
    U0559h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Rat Fatty acid-binding protein, intestinal
    Cat.:
    U0559p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Fatty acid-binding protein, intestinal
    Cat.:
    U0559r
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat Fatty acid-binding protein, intestinal
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    P0559Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Fatty acid-binding protein, intestinal
    Cat.:
    P0559Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Fatty acid-binding protein, intestinal
    Cat.:
    P0559Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Fatty acid-binding protein, intestinal
    Polyclonal Antibody for Rat Fatty acid-binding protein, intestinal
    Monoclonal Antibody for Rat Fatty acid-binding protein, intestinal
    Monoclonal Antibody for Rat Fatty acid-binding protein, intestinal
    Monoclonal Antibody for Rat Fatty acid-binding protein, intestinal
    Monoclonal Antibody for Rat Fatty acid-binding protein, intestinal
    Monoclonal Antibody for Rat Fatty acid-binding protein, intestinal
    Protein for Rat Fatty acid-binding protein, intestinal
    Protein for Rat Fatty acid-binding protein, intestinal
    Protein for Rat Fatty acid-binding protein, intestinal
    Protein for Rat Fatty acid-binding protein, intestinal
    Protein for Rat Fatty acid-binding protein, intestinal

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of a cDNA encoding rat intestinal fatty acid binding protein."
      Alpers D.H. , Strauss A.W. , Ockner R.K. , Bass N.M. , Gordon J.I.
      Proc. Natl. Acad. Sci. U.S.A.81:313-317(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2
    2. 2.
      "Analyzing the structures, functions and evolution of two abundant gastrointestinal fatty acid binding proteins with recombinant DNA and computational techniques."
      Gordon J.I. , Lowe J.B.
      Chem. Phys. Lipids38:137-158(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
    3. 3.
      "The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships."
      Sweetser D.A. , Birkenmeier E.H. , Klisak I.J. , Zollman S. , Sparkes R.S. , Mohandas T. , Lusis A.J. , Gordon J.I.
      J. Biol. Chem.262:16060-16071(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-80
    4. 4.
      "Temperature-induced conformational switch in intestinal fatty acid binding protein (IFABP) revealing an alternative mode for ligand binding."
      Arighi C.N. , Rossi J.P.F.C. , Delfino J.M.
      Biochemistry42:7539-7551(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-34;LIGAND-BINDING
    5. 5.
      "Evidence for a role of the gut hormone PYY in the regulation of intestinal fatty acid-binding protein transcripts in differentiated subpopulations of intestinal epithelial cell hybrids."
      Hallden G. , Aponte G.W.
      J. Biol. Chem.272:12591-12600(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION BY PEPTIDE YY
    6. 6.
      "Turn scanning by site-directed mutagenesis: application to the protein folding problem using the intestinal fatty acid binding protein."
      Kim K. , Frieden C.
      Protein Sci.7:1821-1828(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF GLY-45; ASN-55; GLY-66; GLY-76; GLY-81; GLY-87; ASP-98; GLY-100; GLY-111 AND GLY-122
    7. 7.
      "Crystal structure of rat intestinal fatty-acid-binding protein. Refinement and analysis of the Escherichia coli-derived protein with bound palmitate."
      Sacchettini J.C. , Gordon J.I. , Banaszak L.J.
      J. Mol. Biol.208:327-339(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH PALMITATE
    8. 8.
      "Refined apoprotein structure of rat intestinal fatty acid binding protein produced in Escherichia coli."
      Sacchettini J.C. , Gordon J.I. , Banaszak L.J.
      Proc. Natl. Acad. Sci. U.S.A.86:7736-7740(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.96 ANGSTROMS)
    9. 9.
      "Refinement of the structure of recombinant rat intestinal fatty acid-binding apoprotein at 1.2-A resolution."
      Scapin G. , Gordon J.I. , Sacchettini J.C.
      J. Biol. Chem.267:4253-4269(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.19 ANGSTROMS)
    10. 10.
      "Escherichia coli-derived rat intestinal fatty acid binding protein with bound myristate at 1.5 A resolution and I-FABP Arg106-->Gln with bound oleate at 1.74 A resolution."
      Eads J. , Sacchettini J.C. , Kromminga A. , Gordon J.I.
      J. Biol. Chem.268:26375-26385(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) IN COMPLEX WITH MYRISTATE
    11. 11.
      "Discrete backbone disorder in the nuclear magnetic resonance structure of apo intestinal fatty acid-binding protein: implications for the mechanism of ligand entry."
      Hodsdon M.E. , Cistola D.P.
      Biochemistry36:1450-1460(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
    12. 12.
      "Properties and crystal structure of a beta-barrel folding mutant."
      Ropson I.J. , Yowler B.C. , Dalessio P.M. , Banaszak L. , Thompson J.
      Biophys. J.78:1551-1560(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS);MUTAGENESIS OF VAL-61
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