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Index > Protein center > Fam21(Gene name) > Mouse
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  • Fam21 (Gene name),
  • WASH complex subunit FAM21 (Protein name ),  FAM21_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Fam21(D6Wsu116e;Kiaa0592);
    Protein name:
    WASH complex subunit FAM21;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the WASH complex, composed of F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta (CAPZB), WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53 (By similarity). Interacts (via WHD1 region) with WASH1; the interaction is direct.
    Function:
    Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. In the complex, it probably mediates the recruitment of the complex to endosome membranes.
    Subcellular Location:
    Early endosome membrane
    Protein Attributes:
    Sequence length:
    1334
    Sequence:
    50:
    MNRTSPDSER | PPASEPVWER | PWSVEEIRRS | SQNWSLAADA | GLLQFLQEFS | 
    100:
    QQTISRTHEI | KKQVDGLIQE | TKATHCRLHN | VFNDFLMLSN | TQFIENRVYD | 
    150:
    EEVEEQVLKA | EAEKAEQEKT | REQKEIDLIP | KVQEAVNYGL | QVLDSAFEQL | 
    200:
    DIKAGNSDSE | EDDANERVDL | ILEPKDLYID | RPLPYLIGSK | LFMEQEDVGL | 
    250:
    GELSSEEGSV | GSDRGSIVDS | EDEKEEEESD | EDFASHSDND | QNQHTTQISD | 
    300:
    EEEDDDGDLF | ADSEKEGDDI | EDIEESAKSK | RPTSFADELA | ARIKGDISNQ | 
    350:
    RKEGQTDGKP | QKTVKEKKER | RTPADDEEDI | LFPPPTLTDE | DFSPFGSRGG | 
    400:
    LFSNGQGLFD | DEDESDLFKE | APRARPAQAP | VSEELPPSPK | PGKKIPAGAV | 
    450:
    SVLLGHPDVS | GSTSAPSLKE | LQKHGQPTPG | KSSHLPTPAG | LFDDDDNDND | 
    500:
    EDDNNFFMPS | SSKPSKTDKV | KSTAIIFDDD | EGDLFKEKAE | ALPAASVSQT | 
    550:
    HESKTRADKT | IALPSSKNLK | LVSETKTQKG | LFSDEEDSED | LFSSQSSSKP | 
    600:
    KSASLPSSQP | PTSVSLFGDE | DEEDSLFGSA | AAKKQTSSLQ | PQSQEKAKPS | 
    650:
    EQPSKKTSAL | LFSSDEEDQW | NIADSHTKLA | SDNKSKGELW | DSGATQGQEA | 
    700:
    KAVKKTNLFE | DDDDDEVDLF | AIAKDSQKKT | QRTSLLFEDD | AESGSSLFGL | 
    750:
    PPTSVPSATT | KKESVPKVPL | LFSDEEDSEV | PSGVKPEDLK | VDNARVSPEV | 
    800:
    GSADVASIAQ | KEGLLPASDQ | EAGGPSDIFS | SSSPLDKGAK | GRTRTVLSLF | 
    850:
    DEDEDKVEDE | SSTCAPQDGR | EKGLKTDSRP | KSTGVFQDEE | LLFSHKLQKD | 
    900:
    NDPDVDLFAG | TKKIRSSVPS | GGSLFGDDED | DDLFSSAKTQ | PVVPEKKGTL | 
    950:
    KKDHPVSLKN | QDPLDSTQGS | KEKSTWKTEP | AQDSSGLTPF | KSREPSSRIG | 
    1000:
    KIQANLAINP | AALLPTVALQ | IPGTKPVSSE | LAFPSSEPGR | SHILESVPTL | 
    1050:
    PGSVEAGVSF | DLPAQADTLH | SANKSRVKVR | GKRRPQTRAA | RRLAAQESSE | 
    1100:
    AEDVTVDRGP | VAQLSSSPVL | PNGHQPLLQP | RMASGQTSSE | TATAPPWEGG | 
    1150:
    PVLSAADRSF | FVKSRPQTGN | EADLFDSGDI | FPKSRGSQSV | EGAGVMAGEP | 
    1200:
    PSHSSGGRKE | KSLAFPDLSE | GSSTEDLFQS | VKPRAAKNRN | PFPLLEDEED | 
    1250:
    LFADPRGKKN | ERKPDSHQDS | VSKTHDIFED | DIFATEAIKP | FPKKREKGRT | 
    1300:
    LEPNLFDDNI | DIFADLTVKP | KEKSKKKVAA | KSMFDDDTDD | IFSSGLQAKA | 
    1334:
    SKPKSQSAEA | ASEQRSEHKV | ASIFDDPLNA | FGSQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse WASH complex subunit FAM21
    ELISA Kit for Mouse WASH complex subunit FAM21
    CLIA Kit for Mouse WASH complex subunit FAM21
    CLIA Kit for Mouse WASH complex subunit FAM21
    Polyclonal Antibody for Mouse WASH complex subunit FAM21
    Polyclonal Antibody for Mouse WASH complex subunit FAM21
    Monoclonal Antibody for Mouse WASH complex subunit FAM21
    Monoclonal Antibody for Mouse WASH complex subunit FAM21
    Protein for Mouse WASH complex subunit FAM21
    Protein for Mouse WASH complex subunit FAM21

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Aizawa H. , Yuasa S. , Nakajima D. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Head.
      tissue: Thymus.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6.
      strain: FVB/N-3.
      tissue: Brain.
      tissue: Mammary tumor.
    4. 4.
      "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
      Munton R.P. , Tweedie-Cullen R. , Livingstone-Zatchej M. , Weinandy F. , Waidelich M. , Longo D. , Gehrig P. , Potthast F. , Rutishauser D. , Gerrits B. , Panse C. , Schlapbach R. , Mansuy I.M.
      Mol. Cell. Proteomics6:283-293(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain cortex.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-747;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    6. 6.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-157; SER-159; SER-284; SER-388; SER-533; SER-613; SER-614; SER-723; SER-747; SER-1169; SER-1172; SER-1173 AND SER-1333;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
      Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-614 AND SER-747;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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