Protein name:
High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor ;
Alternative:
Fc alpha/mu receptor (mFcamR) ;
CD:
CD351 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates their endocytosis. May function in the immune response to microbes mediated by IgA and IgM.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MDQGAPAKPS | EQKVPSLRTR | WEILLLTLCL | LHGSSMTPPH | RRSHSRWLQA |
100:
GSPQFRTHLY | NVEAHTAPTP | LCCWKNSLSG | TNALRGPRLV | TGNTGGAVTI |
150:
HCHYAPSSVN | RHQRKYWCRL | GSPLWICHTV | VSTNQYTHPD | YRGRAALTDI |
200:
PQSGLFVVRL | LRLSLGDVGL | YRCGIGDRND | MLFFSVNLTV | SAGPSNTTYA |
250:
AAPASGEPTT | ASPGAASSAG | NGWTSGITQI | LEGSGSEWDR | TVPTTGTSKT |
300:
TSSANGRQTL | RTARTMVPGT | GSREEGSIRA | AVPTPEGPSP | KSRSMSSTTQ |
350:
GVWLWSTRNS | VTPSVTTSEG | RRQGTTPETD | GPRDETDVRV | SPEAPRKTTG |
400:
TTRPSALISE | HVTWETLQDK | TEVSKQQMLH | SLEELSPAPS | AQTLNATCLE |
450:
VASEEGRSID | GSLENTTEES | SPPTPSQLSV | AGPVWVSVKG | PSMKSALMEG |
500:
ESHTRILTPV | STVLALLLIA | ALILLKRSLG | RQRTSQKKER | VPRITLIQMT |
535:
HFLPDKLPDE | GKNFQQSNLL | PPQASLTVLE | NDPRP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
ELISA Kit for Mouse High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
CLIA Kit for Mouse High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
CLIA Kit for Mouse High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
Polyclonal Antibody for Mouse High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
Polyclonal Antibody for Mouse High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
Monoclonal Antibody for Mouse High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
Monoclonal Antibody for Mouse High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
Protein for Mouse High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
Protein for Mouse High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes."
Shibuya A.
,
Sakamoto N.
,
Shimizu Y.
,
Shibuya K.
,
Osawa M.
,
Hiroyama T.
,
Eyre H.J.
,
Sutherland G.R.
,
Endo Y.
,
Fujita T.
,
Miyabayashi T.
,
Sakano S.
,
Tsuji T.
,
Nakayama E.
,
Phillips J.H.
,
Lanier L.L.
,
Nakauchi H.
Nat. Immunol.1:441-446(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MUTAGENESIS OF LEU-519 AND LEU-520
tissue :
T-cell .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
3.
"Fc(alpha)/mu receptor is a single gene-family member closely related to polymeric immunoglobulin receptor encoded on Chromosome 1."
Shimizu Y.
,
Honda S.
,
Yotsumoto K.
,
Tahara-Hanaoka S.
,
Eyre H.J.
,
Sutherland G.R.
,
Endo Y.
,
Shibuya K.
,
Koyama A.
,
Nakauchi H.
,
Shibuya A.
Immunogenetics53:709-711(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 81-535 (ISOFORM 1)
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION