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Index > Protein center > Fdft1(Gene name) > Rat
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  • Fdft1 (Gene name),
  • Squalene synthase (Protein name ),  FDFT_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Fdft1;
    Protein name:
    Squalene synthase(SQS;SS);
    Alternative:
    Farnesyl-diphosphate farnesyltransferase;FPP:FPP farnesyltransferase;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    416
    Sequence:
    50:
    MEFVKCLGHP | EEFYNLLRFR | MGGRRNFIPK | MDRNSLSNSL | KTCYKYLDQT | 
    100:
    SRSFAAVIQA | LDGDIRHAVC | VFYLILRAMD | TVEDDMAISV | EKKIPLLRNF | 
    150:
    HTFLYEPEWR | FTESKEKHRV | VLEDFPTISL | EFRNLAEKYQ | TVIADICHRM | 
    200:
    GCGMAEFLNK | DVTSKQDWDK | YCHYVAGLVG | IGLSRLFSAS | EFEDPIVGED | 
    250:
    TECANSMGLF | LQKTNIIRDY | LEDQQEGRQF | WPQEVWGKYV | KKLEDFVKPE | 
    300:
    NVDVAVKCLN | ELITNALQHI | PDVITYLSRL | RNQSVFNFCA | IPQVMAIATL | 
    350:
    AACYNNHQVF | KGVVKIRKGQ | AVTLMMDATN | MPAVKAIIYQ | YIEEIYHRVP | 
    400:
    NSDPSASKAK | QLISNIRTQS | LPNCQLISRS | HYSPIYLSFI | MLLAALSWQY | 
    416:
    LSTLSQVTED | YVQREH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat SQS
    Cat.:
    E1708h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat SQS
    Cat.:
    E1708r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Rat SQS
    Cat.:
    E1708b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat SQS
    Cat.:
    E1708m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SQS
    Cat.:
    U1708b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SQS
    Cat.:
    U1708m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SQS
    Cat.:
    U1708h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat SQS
    Cat.:
    U1708r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat SQS
    Cat.:
    P1708Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat SQS
    Cat.:
    P1708Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat SQS
    Polyclonal Antibody for Rat SQS
    Cat.:
    P1708Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat SQS
    Monoclonal Antibody for Rat SQS
    Monoclonal Antibody for Rat SQS
    Monoclonal Antibody for Rat SQS
    Protein for Rat SQS
    Protein for Rat SQS
    Protein for Rat SQS
    Protein for Rat SQS

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    Linearity
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    References
    1. 1.
      "Solubilization, purification, and characterization of a truncated form of rat hepatic squalene synthetase."
      Shechter I. , Klinger E. , Rucker M.L. , Engstrom R.G. , Spirito J.A. , Islam M.A. , Boettcher B.R. , Wienstein D.B.
      J. Biol. Chem.267:8628-8635(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Molecular cloning, expression, and characterization of the cDNA for the rat hepatic squalene synthase."
      McKenzie T.L. , Jiang G. , Straubhaar J.R. , Conrad D.G. , Shechter I.
      J. Biol. Chem.267:21368-21374(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Heart.
    4. 4.
      "Subcellular localization of squalene synthase in rat hepatic cells. Biochemical and immunochemical evidence."
      Stamellos K.D. , Shackelford J.E. , Schechter I. , Jiang G. , Conrad D.G. , Keller G.-A. , Krisans S.K.
      J. Biol. Chem.268:12825-12836(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
      tissue: Liver.
    5. 5.
      "Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat."
      Mori M. , Li G. , Abe I. , Nakayama J. , Guo Z. , Sawashita J. , Ugawa T. , Nishizono S. , Serikawa T. , Higuchi K. , Shumiya S.
      J. Clin. Invest.116:395-404(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
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