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Index > Protein center > CFHR1(Gene name) > Human
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  • CFHR1 (Gene name),
  • Complement factor H-related protein 1 (Protein name ),  FHR1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CFHR1(CFHL;CFHL1;CFHL1P;CFHR1P;FHR1;HFL1;HFL2);
    Protein name:
    Complement factor H-related protein 1(FHR-1);
    Alternative:
    H36;H factor-like protein 1(H-factor-like 1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    330
    Sequence:
    50:
    MWLLVSVILI | SRISSVGGEA | TFCDFPKINH | GILYDEEKYK | PFSQVPTGEV | 
    100:
    FYYSCEYNFV | SPSKSFWTRI | TCTEEGWSPT | PKCLRLCFFP | FVENGHSESS | 
    150:
    GQTHLEGDTV | QIICNTGYRL | QNNENNISCV | ERGWSTPPKC | RSTDTSCVNP | 
    200:
    PTVQNAHILS | RQMSKYPSGE | RVRYECRSPY | EMFGDEEVMC | LNGNWTEPPQ | 
    250:
    CKDSTGKCGP | PPPIDNGDIT | SFPLSVYAPA | SSVEYQCQNL | YQLEGNKRIT | 
    300:
    CRNGQWSEPP | KCLHPCVISR | EIMENYNIAL | RWTAKQKLYL | RTGESAEFVC | 
    330:
    KRGYRLSSRS | HTLRTTCWDG | KLEYPTCAKR | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    SMR:
    KEGG:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human FHR-1
    Cat.:
    E2572h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human FHR-1
    Cat.:
    U2572h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human FHR-1
    Cat.:
    P2572Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human FHR-1
    Protein for Human FHR-1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Cloning of the 1.4-kb mRNA species of human complement factor H reveals a novel member of the short consensus repeat family related to the carboxy terminal of the classical 150-kDa molecule."
      Estaller C. , Koistinen V. , Schwaeble W. , Dierich M.P. , Weiss E.H.
      J. Immunol.146:3190-3196(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS TYR-157; VAL-159 AND GLN-175
      tissue: Liver.
    2. 2.
      "Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes."
      Male D.A. , Ormsby R.J. , Ranganathan S. , Giannakis E. , Gordon D.L.
      Mol. Immunol.37:41-52(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS TYR-157; VAL-159 AND GLN-175
      tissue: Liver.
    4. 4.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
      tissue: Skeletal muscle.
    6. 6.
      "Molecular cloning of a human serum protein structurally related to complement factor H."
      Skerka C. , Horstmann R.D. , Zipfel P.F.
      J. Biol. Chem.266:12015-12020(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-330;VARIANTS TYR-157; VAL-159 AND GLN-175
    7. 7.
      "Two major serum components antigenically related to complement factor H are different glycosylation forms of a single protein with no factor H-like complement regulatory functions."
      Timmann C. , Leippe M. , Horstmann R.D.
      J. Immunol.146:1265-1270(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE OF CARBOHYDRATES
    8. 8.
      "Complement factor H and related proteins: an expanding family of complement-regulatory proteins?"
      Zipfel P.F. , Skerka C.
      Immunol. Today15:121-126(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    9. 9.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-126 AND ASN-194
      tissue: Plasma.
    10. 10.
      "Dimerization of complement factor H-related proteins modulates complement activation in vivo."
      Goicoechea de Jorge E. , Caesar J.J. , Malik T.H. , Patel M. , Colledge M. , Johnson S. , Hakobyan S. , Morgan B.P. , Harris C.L. , Pickering M.C. , Lea S.M.
      Proc. Natl. Acad. Sci. U.S.A.110:4685-4690(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.99 ANGSTROMS) OF 19-143;FUNCTION;SUBUNIT;DISULFIDE BONDS
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