FLG ELISA Kit for Human(Homo sapiens) | EIAab.comFLG ELISA Kit for Human(Homo sapiens)

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Index > Protein center > FLG(Gene name) > Human

FLG (Gene name),

Filaggrin (Protein name ), FILA_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FLG;

Protein name:

Filaggrin;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

4061

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FSQSQRYYYY | E

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000357789

Pfam:

PF03516

UniGene:

Hs.654510

MIM:

135940

String:

P20930

KEGG:

hsa:2312

SMR:

P20930

Uniprot:

P20930

FOR

ELISA Kit for Human Filaggrin

Cat.:

E1186m

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human Filaggrin

Cat.:

E1186h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Filaggrin

Cat.:

U1186h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Filaggrin

MSDS:

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Polyclonal Antibody for Human Filaggrin

Cat.:

P1186Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Filaggrin

Protein for Human Filaggrin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.

"Characterization of the human epidermal profilaggrin gene. Genomic organization and identification of an S-100-like calcium binding domain at the amino terminus."
Presland R.B. , Haydock P.V. , Fleckman P. , Nirunsuksiri W. , Dale B.A.
J. Biol. Chem.267:23772-23781(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-591;TISSUE SPECIFICITY
3.

"Characterization of a cDNA clone encoding human filaggrin and localization of the gene to chromosome region 1q21."
McKinley-Grant L.J. , Idler W.W. , Bernstein I.A. , Parry D.A.D. , Cannizzaro L. , Croce C.M. , Huebner K. , Lessin S.R. , Steinert P.M.
Proc. Natl. Acad. Sci. U.S.A.86:4848-4852(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2389-2804
4.

"Identification of the amino terminus of human filaggrin using differential LC/MS techniques: implications for profilaggrin processing."
Thulin C.D. , Walsh K.A.
Biochemistry34:8687-8692(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2741-2760 AND 3065-3084;N-TERMINAL PROCESSING
tissue: Foreskin.
5.

"Preferential deimination of keratin K1 and filaggrin during the terminal differentiation of human epidermis."
Senshu T. , Kan S. , Ogawa H. , Manabe M. , Asaga H.
Biochem. Biophys. Res. Commun.225:712-719(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CITRULLINATION
6.

"Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations."
Weidinger S. , Illig T. , Baurecht H. , Irvine A.D. , Rodriguez E. , Diaz-Lacava A. , Klopp N. , Wagenpfeil S. , Zhao Y. , Liao H. , Lee S.P. , Palmer C.N.A. , Jenneck C. , Maintz L. , Hagemann T. , Behrendt H. , Ring J. , Nothen M.M. , more...
J. Allergy Clin. Immunol.118:214-219(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SUSCEPTIBILITY TO ATOD2
7.

"Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march."
Marenholz I. , Nickel R. , Rueschendorf F. , Schulz F. , Esparza-Gordillo J. , Kerscher T. , Grueber C. , Lau S. , Worm M. , Keil T. , Kurek M. , Zaluga E. , Wahn U. , Lee Y.-A.
J. Allergy Clin. Immunol.118:866-871(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SUSCEPTIBILITY TO ATOD2
8.

"Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris."
Smith F.J.D. , Irvine A.D. , Terron-Kwiatkowski A. , Sandilands A. , Campbell L.E. , Zhao Y. , Liao H. , Evans A.T. , Goudie D.R. , Lewis-Jones S. , Arseculeratne G. , Munro C.S. , Sergeant A. , O'Regan G. , Bale S.J. , Compton J.G. , DiGiovanna J.J. , Presland R.B. , more...
Nat. Genet.38:337-342(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN ICHTHYOSIS VULGARIS
9.

"Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis."
Palmer C.N.A. , Irvine A.D. , Terron-Kwiatkowski A. , Zhao Y. , Liao H. , Lee S.P. , Goudie D.R. , Sandilands A. , Campbell L.E. , Smith F.J.D. , O'Regan G.M. , Watson R.M. , Cecil J.E. , Bale S.J. , Compton J.G. , DiGiovanna J.J. , Fleckman P. , Lewis-Jones S. , more...
Nat. Genet.38:441-446(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SUSCEPTIBILITY TO ATOD2
10.

"Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis."
Nomura T. , Sandilands A. , Akiyama M. , Liao H. , Evans A.T. , Sakai K. , Ota M. , Sugiura H. , Yamamoto K. , Sato H. , Palmer C.N.A. , Smith F.J.D. , McLean W.H.I. , Shimizu H.
J. Allergy Clin. Immunol.119:434-440(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SUSCEPTIBILITY TO ATOD2

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