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Index > Protein center > FLOT1(Gene name) > Human
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  • FLOT1 (Gene name),
  • Flotillin-1 (Protein name ),  FLOT1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FLOT1;
    Protein name:
    Flotillin-1;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2 (By similarity). Interacts with ECM29.
    Function:
    May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
    Subcellular Location:
    Cell membrane Peripheral membrane protein Membrane caveola Peripheral membrane protein Melanosome Endosome Membrane-associated protein of caveolae. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    Protein Attributes:
    Sequence length:
    427
    Sequence:
    50:
    MFFTCGPNEA | MVVSGFCRSP | PVMVAGGRVF | VLPCIQQIQR | ISLNTLTLNV | 
    100:
    KSEKVYTRHG | VPISVTGIAQ | VKIQGQNKEM | LAAACQMFLG | KTEAEIAHIA | 
    150:
    LETLEGHQRA | IMAHMTVEEI | YKDRQKFSEQ | VFKVASSDLV | NMGISVVSYT | 
    200:
    LKDIHDDQDY | LHSLGKARTA | QVQKDARIGE | AEAKRDAGIR | EAKAKQEKVS | 
    250:
    AQYLSEIEMA | KAQRDYELKK | AAYDIEVNTR | RAQADLAYQL | QVAKTKQQIE | 
    300:
    EQRVQVQVVE | RAQQVAVQEQ | EIARREKELE | ARVRKPAEAE | RYKLERLAEA | 
    350:
    EKSQLIMQAE | AEAASVRMRG | EAEAFAIGAR | ARAEAEQMAK | KAEAFQLYQE | 
    400:
    AAQLDMLLEK | LPQVAEEISG | PLTSANKITL | VSSGSGTMGA | AKVTGEVLDI | 
    427:
    LTRLPESVER | LTGVSISQVN | HKPLRTA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    SMR:
    UniGene:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Flotillin-1
    MSDS:
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    ELISA Kit for Human Flotillin-1
    Cat.:
    E11843m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Flotillin-1
    Cat.:
    E11843r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Flotillin-1
    Cat.:
    E11843h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Flotillin-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Flotillin-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Flotillin-1
    Cat.:
    U11843h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Flotillin-1
    Cat.:
    U11843r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Flotillin-1
    Cat.:
    U11843m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Flotillin-1
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Human Flotillin-1
    Polyclonal Antibody for Human Flotillin-1
    Polyclonal Antibody for Human Flotillin-1
    Polyclonal Antibody for Human Flotillin-1
    Polyclonal Antibody for Human Flotillin-1
    Cat.:
    P11843Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Flotillin-1
    Monoclonal Antibody for Human Flotillin-1
    Monoclonal Antibody for Human Flotillin-1
    Monoclonal Antibody for Human Flotillin-1
    Monoclonal Antibody for Human Flotillin-1
    Protein for Human Flotillin-1
    Protein for Human Flotillin-1
    Protein for Human Flotillin-1
    Protein for Human Flotillin-1
    Protein for Human Flotillin-1

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    Linearity
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    References
    1. 1.
      "Flotillin-1: gene structure: cDNA cloning from human lung and the identification of alternative polyadenylation signals."
      Edgar A.J. , Polak J.M.
      Int. J. Biochem. Cell Biol.33:53-64(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Lung.
    2. 2.
      "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells."
      Zhang Q.-H. , Ye M. , Wu X.-Y. , Ren S.-X. , Zhao M. , Zhao C.-J. , Fu G. , Shen Y. , Fan H.-Y. , Lu G. , Zhong M. , Xu X.-R. , Han Z.-G. , Zhang J.-W. , Tao J. , Huang Q.-H. , Zhou J. , Hu G.-X. , more...
      Genome Res.10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Umbilical cord blood.
    3. 3.
      "Homo sapiens 2,229,817bp genomic DNA of 6p21.3 HLA class I region."
      Shiina S. , Tamiya G. , Oka A. , Inoko H.
      Submitted (1999-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Stomach.
    5. 5.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Lung.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-253 (ISOFORM 1)
      tissue: Adrenal gland.
    8. 8.
      "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."
      Chi A. , Valencia J.C. , Hu Z.-Z. , Watabe H. , Yamaguchi H. , Mangini N.J. , Huang H. , Canfield V.A. , Cheng K.C. , Yang F. , Abe R. , Yamagishi S. , Shabanowitz J. , Hearing V.J. , Wu C. , Appella E. , Hunt D.F.
      J. Proteome Res.5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
      tissue: Melanoma.
    9. 9.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-19;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-385;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    12. 12.
      "A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components."
      Gorbea C. , Pratt G. , Ustrell V. , Bell R. , Sahasrabudhe S. , Hughes R.E. , Rechsteiner M.
      J. Biol. Chem.285:31616-31633(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH ECM29
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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