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Index > Protein center > Folr1(Gene name) > Mouse
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  • Folr1 (Gene name),
  • Folate receptor alpha (Protein name ),  FOLR1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Folr1(Fbp1;Folbp1);
    Protein name:
    Folate receptor alpha(FR-alpha);
    Alternative:
    Folate-binding protein 1;Folate receptor 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    255
    Sequence:
    50:
    MAHLMTVQLL | LLVMWMAECA | QSRATRARTE | LLNVCMDAKH | HKEKPGPEDN | 
    100:
    LHDQCSPWKT | NSCCSTNTSQ | EAHKDISYLY | RFNWNHCGTM | TSECKRHFIQ | 
    150:
    DTCLYECSPN | LGPWIQQVDQ | SWRKERILDV | PLCKEDCQQW | WEDCQSSFTC | 
    200:
    KSNWHKGWNW | SSGHNECPVG | ASCHPFTFYF | PTSAALCEEI | WSHSYKLSNY | 
    250:
    SRGSGRCIQM | WFDPAQGNPN | EEVARFYAEA | MSGAGLHGTW | PLLCSLSLVL | 
    255:
    LWVIS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse FR-alpha
    Cat.:
    E1599h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse FR-alpha
    Cat.:
    E1599m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse FR-alpha
    Cat.:
    E1599b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse FR-alpha
    Cat.:
    U1599m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse FR-alpha
    Cat.:
    U1599b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse FR-alpha
    Cat.:
    U1599h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse FR-alpha
    Polyclonal Antibody for Mouse FR-alpha
    Cat.:
    P1599Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse FR-alpha
    Cat.:
    P1599Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse FR-alpha
    Monoclonal Antibody for Mouse FR-alpha
    Monoclonal Antibody for Mouse FR-alpha
    Protein for Mouse FR-alpha
    Protein for Mouse FR-alpha
    Protein for Mouse FR-alpha

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement."
      Brigle K.E. , Westin E.H. , Houghton M.T. , Goldman I.D.
      J. Biol. Chem.266:17243-17249(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION
    2. 2.
      "Retinoic acid-dependent upregulation of mouse folate receptor-alpha expression in embryonic stem cells, and conservation of alternative splicing patterns."
      Bolton J.A. , Wood S.A. , Kennedy D. , Don R.H. , Mattick J.S.
      Gene230:215-224(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INDUCTION
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    6. 6.
      "Insertion of an intracisternal A particle within the 5'-regulatory region of a gene encoding folate-binding protein in L1210 leukemia cells in response to low folate selection. Association with increased protein expression."
      Brigle K.E. , Westin E.H. , Houghton M.T. , Goldman I.D.
      J. Biol. Chem.267:22351-22355(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-54
    7. 7.
      "Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development."
      Piedrahita J.A. , Oetama B. , Bennett G.D. , van Waes J. , Kamen B.A. , Richardson J. , Lacey S.W. , Anderson R.G. , Finnell R.H.
      Nat. Genet.23:228-232(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    9. 9.
      "Developmental consequences of abnormal folate transport during murine heart morphogenesis."
      Tang L.S. , Wlodarczyk B.J. , Santillano D.R. , Miranda R.C. , Finnell R.H.
      Birth Defects Res. A Clin. Mol. Teratol.70:449-458(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
    10. 10.
      "Renal tubular reabsorption of folate mediated by folate binding protein 1."
      Birn H. , Spiegelstein O. , Christensen E.I. , Finnell R.H.
      J. Am. Soc. Nephrol.16:608-615(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
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