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Index > Protein center > FTH1(Gene name) > Human
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  • FTH1 (Gene name),
  • Ferritin heavy chain (Protein name ),  FRIH_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    FTH1(OK/SW-cl.84;PIG15;FTH;FTHL6);
    Protein name:
    Ferritin heavy chain(Ferritin H subunit);
    Alternative:
    Cell proliferation-inducing gene 15 protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
    Function:
    Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    183
    Sequence:
    50:
    MTTASTSQVR | QNYHQDSEAA | INRQINLELY | ASYVYLSMSY | YFDRDDVALK | 
    100:
    NFAKYFLHQS | HEEREHAEKL | MKLQNQRGGR | IFLQDIKKPD | CDDWESGLNA | 
    150:
    MECALHLEKN | VNQSLLELHK | LATDKNDPHL | CDFIETHYLN | EQVKAIKELG | 
    183:
    DHVTNLRKMG | APESGLAEYL | FDKHTLGDSD | NES
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    Pfam:
    MIM:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Ferritin H subunit
    Cat.:
    E0518r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Ferritin H subunit
    Cat.:
    E0518h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Ferritin H subunit
    MSDS:
    Please sign in first.
    ELISA Kit for Human Ferritin H subunit
    Cat.:
    E0518m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Ferritin H subunit
    Cat.:
    E0518p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Ferritin H subunit
    Cat.:
    E0518b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Ferritin H subunit
    Cat.:
    E0518d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Ferritin H subunit
    Cat.:
    U0518d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Ferritin H subunit
    MSDS:
    Please sign in first.
    CLIA Kit for Human Ferritin H subunit
    Cat.:
    U0518h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Ferritin H subunit
    Cat.:
    U0518r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Ferritin H subunit
    Cat.:
    U0518m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Ferritin H subunit
    Cat.:
    U0518b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Ferritin H subunit
    Cat.:
    U0518p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Ferritin H subunit
    Cat.:
    P0518Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Ferritin H subunit
    Polyclonal Antibody for Human Ferritin H subunit
    Cat.:
    P0518Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Ferritin H subunit
    Cat.:
    P0518Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Ferritin H subunit
    Polyclonal Antibody for Human Ferritin H subunit
    Polyclonal Antibody for Human Ferritin H subunit
    Monoclonal Antibody for Human Ferritin H subunit
    Monoclonal Antibody for Human Ferritin H subunit
    Monoclonal Antibody for Human Ferritin H subunit
    Monoclonal Antibody for Human Ferritin H subunit
    Cat.:
    M0518h
    Price:
    Please sign in first.
    Packing:
    40ug
    Monoclonal Antibody for Human Ferritin H subunit
    Monoclonal Antibody for Human Ferritin H subunit
    Monoclonal Antibody for Human Ferritin H subunit
    Protein for Human Ferritin H subunit
    Protein for Human Ferritin H subunit
    Protein for Human Ferritin H subunit
    Protein for Human Ferritin H subunit
    Cat.:
    R0518h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human Ferritin H subunit
    Protein for Human Ferritin H subunit
    Protein for Human Ferritin H subunit

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and sequencing of a full length cDNA coding for a human apoferritin H chain: evidence for a multigene family."
      Costanzo F. , Santoro C. , Colantuoni V. , Bensi G. , Raugei G. , Romano V. , Cortese R.
      EMBO J.3:23-27(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Hepatocyte.
    2. 2.
      "Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones."
      Boyd D. , Vecoli C. , Belcher D.M. , Jain S.K. , Drysdale J.W.
      J. Biol. Chem.260:11755-11761(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Structure and expression of ferritin genes in a human promyelocytic cell line that differentiates in vitro."
      Chou C.-C. , Gatti R.A. , Fuller M.L. , Concannon P. , Wong A. , Chada S. , Davis R.C. , Salser W.A.
      Mol. Cell. Biol.6:566-573(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene."
      Hentze M.W. , Keim S. , Papadopoulos P. , O'Brien S. , Modi W. , Drysdale J.W. , Leonard W.J. , Harford J.B. , Klausner R.D.
      Proc. Natl. Acad. Sci. U.S.A.83:7226-7230(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    6. 6.
      "Sequence of a cDNA encoding the ferritin H-chain from an 11-week-old human fetal brain."
      Dhar M. , Chauthaiwale V.M. , Joshi J.G.
      Gene126:275-278(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    7. 7.
      "Cloning of a novel full length cDNA for ferritin heavy chain from normal adult human and Alzheimer's brain."
      Chauthaiwale V.M. , Dhar M. , McLachlan D.R. , Joshi J.G.
      Submitted (1994-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    8. 8.
      "Detection of ferritin heavy chain by SEREX: a multifunctional molecule in malignant tumour cells."
      Franco A.V. , Gray C.P. , Myers K. , Hersey P.
      Submitted (1998-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    9. 9.
      "Identification of a human cell proliferation gene 15."
      Kim J.W.
      Submitted (2003-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    10. 10.
      "Identification of immuno-peptidmics that are recognized by tumor-reactive CTL generated from TIL of colon cancer patients."
      Shichijo S. , Itoh K.
      Submitted (2001-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Colon adenocarcinoma.
    11. 11.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Cerebellum.
    12. 12.
      NHLBI resequencing and genotyping service (RS&G)
      Submitted (2006-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    14. 14.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
      tissue: Cervix.
      tissue: Colon.
      tissue: Lung.
      tissue: Ovary.
      tissue: Prostate.
      tissue: Salivary gland.
    15. 15.
      "Isolation and characterization of a cDNA clone for human ferritin heavy chain."
      Boyd D. , Jain S.K. , Crampton J. , Barrett K.J. , Drysdale J.
      Proc. Natl. Acad. Sci. U.S.A.81:4751-4755(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 128-183
    16. 16.
      "A mutation, in the iron-responsive element of H ferritin mRNA, causing autosomal dominant iron overload."
      Kato J. , Fujikawa K. , Kanda M. , Fukuda N. , Sasaki K. , Takayama T. , Kobune M. , Takada K. , Takimoto R. , Hamada H. , Ikeda T. , Niitsu Y.
      Am. J. Hum. Genet.69:191-197(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN HFE5;TISSUE SPECIFICITY
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      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-179;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
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      Han G. , Ye M. , Zhou H. , Jiang X. , Feng S. , Jiang X. , Tian R. , Wan D. , Zou H. , Gu J.
      Proteomics8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
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      tissue: Liver.
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      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-179;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
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