FUT3 ELISA Kit for Human(Homo sapiens) | EIAab.comFUT3 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > FUT3(Gene name) > Human

FUT3 (Gene name),

Galactoside 3(4)-L-fucosyltransferase (Protein name ), FUT3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FUT3(FT3B;LE);

Protein name:

Galactoside 3(4)-L-fucosyltransferase;

Alternative:

Fucosyltransferase 3;Blood group Lewis alpha-4-fucosyltransferase(Lewis FT);Fucosyltransferase III(FucT-III);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination; Lewis-positive (Le(+)) individuals have an active enzyme while Lewis-negative (Le(-)) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links.

Subcellular Location:

Golgi apparatus Golgi stack membrane Single-pass type II membrane protein Membrane-bound form in trans cisternae of Golgi.

Protein Attributes:

Sequence length:

361

Sequence:

50:

100:

150:

200:

250:

300:

350:

361:

QTVRSIAAWF | T

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:2525

UniGene:

Hs.169238

String:

P21217

MIM:

111100

STRING:

9606.ENSP00000305603

Pfam:

PF00852

SMR:

P21217

Uniprot:

P21217

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ELISA Kit for Human Galactoside 3(4)-L-fucosyltransferase

Cat.:

E8997h

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96T

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ELISA Kit for Human Galactoside 3(4)-L-fucosyltransferase

Cat.:

E8997b

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Packing:

96T

CLIA Kit for Human Galactoside 3(4)-L-fucosyltransferase

Cat.:

U8997b

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Packing:

96T

CLIA Kit for Human Galactoside 3(4)-L-fucosyltransferase

Cat.:

U8997h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Galactoside 3(4)-L-fucosyltransferase

Cat.:

P8997Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Galactoside 3(4)-L-fucosyltransferase

Protein for Human Galactoside 3(4)-L-fucosyltransferase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Alpha (1,3/1,4)fucosyltransferase (FucT-III) gene is inactivated by a single amino acid substitution in Lewis histo-blood type negative individuals."
Nishihara S. , Yazawa S. , Iwasaki H. , Nakazato M. , Kudo T. , Ando T. , Narimatsu H.
Biochem. Biophys. Res. Commun.196:624-631(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LE(-) ARG-20; SER-170 AND ALA-336
2.

"Analysis of Lewis fucosyltransferase genes from the human gastric mucosa of Lewis-positive and -negative individuals."
Koda Y. , Kimura H. , Mekada E.
Blood82:2915-2919(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LE(-) ARG-20 AND SER-170
3.

"Molecular basis for Lewis alpha(1,3/1,4)-fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees."
Mollicone R. , Reguigne I. , Kelly R.J. , Fletcher A. , Watt J. , Chatfield S. , Aziz A. , Cameron H.S. , Weston B.W. , Lowe J.B. , Oriol R.
J. Biol. Chem.269:20987-20994(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LE(-) ARG-20 AND LYS-356
4.

"Molecular genetic analysis of the human Lewis histo-blood group system."
Nishihara S. , Narimatsu H. , Iwasaki H. , Yazawa S. , Akamatsu S. , Ando T. , Seno T. , Narimatsu I.
J. Biol. Chem.269:29271-29278(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LE(-) LYS-356
5.

"DNA sequencing and screening for point mutations in the human Lewis 'FUT3' gene enables molecular genotyping of the human Lewis blood group system."
Elmgren A. , Boerjeson C. , Svensson L. , Rydberg L. , Larson G.
Vox Sang.70:97-103(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LE(-) ARG-20; ARG-68; MET-105 AND LYS-356
6.

"Significance of individual point mutations, T202C and C314T, in the human Lewis 'FUT3' gene for expression of Lewis antigens by the human alpha'1,3/1,4'-fucosyltransferase, Fuc-TIII."
Elmgren A. , Mollicone R. , Costache M. , Boerjeson C. , Oriol R. , Harrington J. , Larson G.
J. Biol. Chem.272:21994-21998(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LE(-) ARG-68 AND MET-105
7.

"Five novel missense mutations of the Lewis gene 'FUT3' in African 'Xhosa' and Caucasian populations in South Africa."
Pang H. , Liu Y. , Koda Y. , Soejima M. , Jia J. , Schlaphoff T. , du Toit E.D. , Kimura H.
Hum. Genet.102:675-680(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LE(+) LYS-102 AND ALA-124;VARIANTS LE(-) ASN-162; ARG-223 AND MET-270
8.

"A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase."
Kukowska-Latallo J.F. , Larsen R.D. , Nair R.P. , Lowe J.B.
Genes Dev.4:1288-1303(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
9.

"Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms."
Cameron H.S. , Szczepaniak D. , Weston B.W.
J. Biol. Chem.270:20112-20122(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Liver.
10.

"Isolation and expression of human alpha (1,3/1,4) fucosyltransferase."
Rahim I. , Schmidt L.R. , Wahl D. , Drayson E. , Maslanik W. , Stranahan P.L. , Pettijohn D.E.
Submitted (1999-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Squamous cell carcinoma.
11.

"Allele frequencies of fucosyltransferases 1, 2, and 3 of Styrian blood donors."
Matzhold E.M.
Submitted (2008-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ARG-68 AND MET-105
tissue: Blood.
12.

SeattleSNPs variation discovery resource
Submitted (2004-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-5; ARG-20; ARG-68; MET-105; CYS-160; ASN-162; SER-170; ARG-223; MET-270; MET-325 AND GLN-327
13.

"The DNA sequence and biology of human chromosome 19."
Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANTS ARG-68 AND MET-105
14.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Colon.
tissue: Lung.
15.

"Genotypic heterogeneity among Lewis negative individuals."
Elmgren A. , Rydberg L. , Larson G.
Biochem. Biophys. Res. Commun.196:515-520(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LE(-) MET-105

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