GADD45GIP1 ELISA Kit for Human(Homo sapiens) | EIAab.comGADD45GIP1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > GADD45GIP1(Gene name) > Human

GADD45GIP1 (Gene name),

Growth arrest and DNA damage-inducible proteins-interacting protein 1 (Protein name ), G45IP_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

GADD45GIP1(PLINP1;PRG6;PRG6);

Protein name:

Growth arrest and DNA damage-inducible proteins-interacting protein 1;

Alternative:

CR6-interacting factor 1(CRIF1);CKII beta-associating protein(MRP-L59);p53-responsive gene 6 protein(PLINP);Papillomavirus L2-interacting nuclear protein 1(PLINP-1);p53-responsive gene 6 protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with GADD45A, GADD45B and GADD45G. Interacts with NR4A1 via the NR4A1 AB domain. Interacts with the human papilloma virus type 16 (HPV 16) minor capsid protein L2.

Function:

Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

222

Sequence:

50:

100:

150:

200:

222:

ARAAALAAAV | AQDPAASGAP | SS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q8TAE8

Pfam:

PF10147

KEGG:

hsa:90480

MIM:

605162

UniGene:

Hs.515164

STRING:

9606.ENSP00000323065

Uniprot:

Q8TAE8

FOR

ELISA Kit for Human Growth arrest and DNA damage-inducible proteins-interacting protein 1

CLIA Kit for Human Growth arrest and DNA damage-inducible proteins-interacting protein 1

Polyclonal Antibody for Human Growth arrest and DNA damage-inducible proteins-interacting protein 1

Monoclonal Antibody for Human Growth arrest and DNA damage-inducible proteins-interacting protein 1

Protein for Human Growth arrest and DNA damage-inducible proteins-interacting protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Interaction of human papillomavirus type 16 L2 with cellular proteins: identification of novel nuclear body-associated proteins."
Goernemann J. , Hofmann T.G. , Will H. , Mueller M.
Virology303:69-78(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;INTERACTION WITH HPV16 L2
tissue: Keratinocyte.
2.

"CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle."
Chung H.K. , Yi Y.-W. , Jung N.-C. , Kim D. , Suh J.M. , Kim H. , Park K.C. , Song J.H. , Kim D.W. , Hwang E.S. , Yoon S.-H. , Bae Y.-S. , Kim J.M. , Bae I. , Shong M.
J. Biol. Chem.278:28079-28088(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;INTERACTION WITH GADD45A; GADD45B AND GADD45G;TISSUE SPECIFICITY
tissue: Colon carcinoma.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
tissue: Muscle.
tissue: Skin.
4.

"Full length sequencing of some human and murine muscular transcripts (Telethon Italy project B41)."
Frigimelica E. , Lanfranchi G.
Submitted (2003-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-222
5.

"Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene."
Horikoshi N. , Cong J. , Kley N. , Shenk T.
Biochem. Biophys. Res. Commun.261:864-869(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 90-122;INDUCTION
6.

"CR6-interacting factor 1 interacts with orphan nuclear receptor Nur77 and inhibits its transactivation."
Park K.C. , Song K.-H. , Chung H.K. , Kim H. , Kim D.W. , Song J.H. , Hwang E.S. , Jung H.S. , Park S.-H. , Bae I. , Lee I.K. , Choi H.-S. , Shong M.
Mol. Endocrinol.19:12-24(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NR4A1/NUR77
7.

"Large-scale proteomics analysis of the human kinome."
Oppermann F.S. , Gnad F. , Olsen J.V. , Hornberger R. , Greff Z. , Keri G. , Mann M. , Daub H.
Mol. Cell. Proteomics8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
9.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.

"Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis."
He J. , Cooper H.M. , Reyes A. , Di Re M. , Sembongi H. , Litwin T.R. , Gao J. , Neuman K.C. , Fearnley I.M. , Spinazzola A. , Walker J.E. , Holt I.J.
Nucleic Acids Res.40:6109-6121(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATAD3A AND ATAD3B;SUBCELLULAR LOCATION
11.

"Identification and characterization of CHCHD1, AURKAIP1, and CRIF1 as new members of the mammalian mitochondrial ribosome."
Koc E.C. , Cimen H. , Kumcuoglu B. , Abu N. , Akpinar G. , Haque M.E. , Spremulli L.L. , Koc H.
Front. Physiol.4:183-183(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;SUBCELLULAR LOCATION

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