Protein name:
GRB2-associated-binding protein 1 ;
Alternative:
Growth factor receptor bound protein 2-associated protein 1 ;GRB2-associated binder 1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2. Interacts with PTPRJ (By similarity). Identified in a complex containing FRS2A, GRB2, GAB1, PIK3R1 and SOS1.
Function:
Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).
Subcellular Location:
N/A
Protein Attributes:
50:
MSGGEVVCSG | WLRKSPPEKK | LKRYAWKRRW | FVLRSGRLTG | DPDVLEYYKN |
100:
DHAKKPIRII | DLNLCQQVDA | GLTFNKKEFE | NSYIFDINTI | DRIFYLVADS |
150:
EEDMNKWVRC | ICDICGFNPT | EEDPVKPLTG | SSQAPVDSPF | AISTAPASSQ |
200:
MEASSVALPP | PYQVISLPPH | PDTLGLQDDP | QDYLLLINCQ | SKKPEPNRTL |
250:
FDSAKPTFSE | TDCNDNVPSH | QTPASSQSKH | GMNGFFQQQM | MYDCPPSRLT |
300:
SVSGESSLYN | LPRSYSHDVL | PKESPSSTEA | DGELYTFNTP | SGTAGVETQM |
350:
RHVSISYDIP | PTPGNTYQIP | RTFPESTLGQ | SSKLDTIPDI | PPPRPPKPHP |
400:
THDRSPVETC | GVPRTASDTD | SSYCIPPPAG | MTPSRSNTIS | TVDLNKLRKD |
450:
ASSQDCYDIP | RTFPSDRSSS | LEGFHSQYKI | KSVLTAGGVS | GEELDENYVP |
500:
MNPNSPPRQH | SGSFTEPIQE | PNYVPMTPGT | FDFSSFGMQV | PPPAHMGFRS |
550:
SPKTPPRRPV | PVADCEPPPV | DRNLKPDRKV | KPAPLDIKPL | SEWEELQAPV |
600:
RSPITRSFAR | DSSRFPMSPR | PDSVHSTTSS | SDSHDSEENY | VPMNPNLSGE |
650:
DPNLFASNSL | DGGSSPMNKP | KGDKQVEYLD | LDLDSGKSTP | PRKQKSSGSG |
695:
SSMADERVDY | VVVDQQKTLA | LKSTREAWTD | GRQSTESETP | TKNVK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Bovine
ELISA Kit for Mouse GRB2-associated-binding protein 1
ELISA Kit for Mouse GRB2-associated-binding protein 1
ELISA Kit for Mouse GRB2-associated-binding protein 1
CLIA Kit for Mouse GRB2-associated-binding protein 1
CLIA Kit for Mouse GRB2-associated-binding protein 1
CLIA Kit for Mouse GRB2-associated-binding protein 1
Polyclonal Antibody for Mouse GRB2-associated-binding protein 1
Polyclonal Antibody for Mouse GRB2-associated-binding protein 1
Polyclonal Antibody for Mouse GRB2-associated-binding protein 1
Monoclonal Antibody for Mouse GRB2-associated-binding protein 1
Monoclonal Antibody for Mouse GRB2-associated-binding protein 1
Monoclonal Antibody for Mouse GRB2-associated-binding protein 1
Protein for Mouse GRB2-associated-binding protein 1
Protein for Mouse GRB2-associated-binding protein 1
Protein for Mouse GRB2-associated-binding protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
Sachs M.
Submitted (1999-10) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION IN RESPONSE TO FGFR1 SIGNALING;INTERACTION WITH GRB2
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON FUNCTION IN FGF SIGNALING