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Index > Protein center > Gab1(Gene name) > Mouse
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  • Gab1 (Gene name),
  • GRB2-associated-binding protein 1 (Protein name ),  GAB1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    Gab1;
    Protein name:
    GRB2-associated-binding protein 1;
    Alternative:
    Growth factor receptor bound protein 2-associated protein 1;GRB2-associated binder 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2. Interacts with PTPRJ (By similarity). Identified in a complex containing FRS2A, GRB2, GAB1, PIK3R1 and SOS1.
    Function:
    Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    695
    Sequence:
    50:
    MSGGEVVCSG | WLRKSPPEKK | LKRYAWKRRW | FVLRSGRLTG | DPDVLEYYKN | 
    100:
    DHAKKPIRII | DLNLCQQVDA | GLTFNKKEFE | NSYIFDINTI | DRIFYLVADS | 
    150:
    EEDMNKWVRC | ICDICGFNPT | EEDPVKPLTG | SSQAPVDSPF | AISTAPASSQ | 
    200:
    MEASSVALPP | PYQVISLPPH | PDTLGLQDDP | QDYLLLINCQ | SKKPEPNRTL | 
    250:
    FDSAKPTFSE | TDCNDNVPSH | QTPASSQSKH | GMNGFFQQQM | MYDCPPSRLT | 
    300:
    SVSGESSLYN | LPRSYSHDVL | PKESPSSTEA | DGELYTFNTP | SGTAGVETQM | 
    350:
    RHVSISYDIP | PTPGNTYQIP | RTFPESTLGQ | SSKLDTIPDI | PPPRPPKPHP | 
    400:
    THDRSPVETC | GVPRTASDTD | SSYCIPPPAG | MTPSRSNTIS | TVDLNKLRKD | 
    450:
    ASSQDCYDIP | RTFPSDRSSS | LEGFHSQYKI | KSVLTAGGVS | GEELDENYVP | 
    500:
    MNPNSPPRQH | SGSFTEPIQE | PNYVPMTPGT | FDFSSFGMQV | PPPAHMGFRS | 
    550:
    SPKTPPRRPV | PVADCEPPPV | DRNLKPDRKV | KPAPLDIKPL | SEWEELQAPV | 
    600:
    RSPITRSFAR | DSSRFPMSPR | PDSVHSTTSS | SDSHDSEENY | VPMNPNLSGE | 
    650:
    DPNLFASNSL | DGGSSPMNKP | KGDKQVEYLD | LDLDSGKSTP | PRKQKSSGSG | 
    695:
    SSMADERVDY | VVVDQQKTLA | LKSTREAWTD | GRQSTESETP | TKNVK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse GRB2-associated-binding protein 1
    ELISA Kit for Mouse GRB2-associated-binding protein 1
    ELISA Kit for Mouse GRB2-associated-binding protein 1
    CLIA Kit for Mouse GRB2-associated-binding protein 1
    CLIA Kit for Mouse GRB2-associated-binding protein 1
    CLIA Kit for Mouse GRB2-associated-binding protein 1
    Polyclonal Antibody for Mouse GRB2-associated-binding protein 1
    Polyclonal Antibody for Mouse GRB2-associated-binding protein 1
    Polyclonal Antibody for Mouse GRB2-associated-binding protein 1
    Monoclonal Antibody for Mouse GRB2-associated-binding protein 1
    Monoclonal Antibody for Mouse GRB2-associated-binding protein 1
    Monoclonal Antibody for Mouse GRB2-associated-binding protein 1
    Protein for Mouse GRB2-associated-binding protein 1
    Protein for Mouse GRB2-associated-binding protein 1
    Protein for Mouse GRB2-associated-binding protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      Sachs M.
      Submitted (1999-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary tumor.
    3. 3.
      "Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins."
      Ong S.H. , Hadari Y.R. , Gotoh N. , Guy G.R. , Schlessinger J. , Lax I.
      Proc. Natl. Acad. Sci. U.S.A.98:6074-6079(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION IN RESPONSE TO FGFR1 SIGNALING;INTERACTION WITH GRB2
    4. 4.
      "Fibroblast growth factor signalling: from development to cancer."
      Turner N. , Grose R.
      Nat. Rev. Cancer10:116-129(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION IN FGF SIGNALING
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