Protein name:
Growth arrest-specific protein 6 (GAS-6) ;
Alternative:
Growth-potentiating factor (GPF) ;AXL receptor tyrosine kinase ligand ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Heterodimer and heterotetramer with AXL.
Function:
Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Subcellular Location:
Secreted
Protein Attributes:
50:
MPPPPGPTAA | LGTALLLLLL | ASESSHTVLL | RAREAAQFLR | PRQRRAYQVF |
100:
EEAKQGHLER | ECVEEVCSKE | EAREVFENDP | ETDYFYPRYQ | ECMRKYGRPE |
150:
DKNPNFATCV | KNLPDQCTPN | PCDKKGTQLC | QDLMGNFFCL | CKDGWGGRLC |
200:
DKDVNECSQK | NGGCSQVCHN | KPGSFQCACH | SGFSLQSDNK | SCQDIDECTD |
250:
SDTCGDARCK | NLPGSYSCLC | DKGYTYSSKE | KTCQDVDECQ | QDRCEQTCVN |
300:
SPGSYTCHCN | GRGGLKLSPD | MDTCEDILPC | VPFSMAKSVK | SLYLGRMFSG |
350:
TPVIRLRFKR | LQPTRLLAEF | DFRTFDPEGV | LFFAGGRSDS | TWIVLGLRAG |
400:
RLELQLRYNG | VGRITSSGPT | INHGMWQTIS | VEELDRNLVI | KVNKDAVMKI |
450:
AVAGGLFQLE | RGLYHLNLTV | GGIPFKESDL | VQPINPRLDG | CMRSWNWLNG |
500:
EDSAIQETVK | ANTKMQCFSV | TERGSFFPGN | GFAFYSLNYT | RTSLDVGTET |
550:
TWEVEVVARI | RPATDTGVLM | ALVGDKDVVL | LSVALVDYHS | TKKLKKQLVV |
600:
LAVENVALAL | MEIKVCDSQE | HTVTVSLRDG | EATLEVDGTK | GQSEVSTAQL |
650:
QERLDLLKTR | LQGSVLTFVG | GLPDVQVTST | PVTAFYRGCM | TLEVNGKTLD |
674:
LDTASYKHSD | ITSHSCPPVE | HVTA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Polyclonal Antibody for Rat GAS-6
Polyclonal Antibody for Rat GAS-6
Polyclonal Antibody for Rat GAS-6
Monoclonal Antibody for Rat GAS-6
Monoclonal Antibody for Rat GAS-6
Monoclonal Antibody for Rat GAS-6
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : RECEPTOR INTERACTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : RECEPTOR INTERACTION
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GAMMA-CARBOXYGLUTAMATION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-609; SER-614; THR-617; THR-633 AND TYR-636;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]