GNB2 ELISA Kit for Human(Homo sapiens) | EIAab.comGNB2 ELISA Kit for Human(Homo sapiens)

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GNB2 (Gene name),

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (Protein name ), GBB2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

GNB2;

Protein name:

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;

Alternative:

Transducin beta chain 2;G protein subunit beta-2;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

G proteins are composed of 3 units, alpha, beta and gamma. Interacts with ARHGEF18 and RASD2. Interacts with ATXN10.

Function:

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Subcellular Location:

Cytoplasm perinuclear region

Protein Attributes:

Sequence length:

340

Sequence:

50:

100:

150:

200:

250:

300:

340:

KGDRAGVLAG | HDNRVSCLGV | TDDGMAVATG | SWDSFLKIWN |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.185172

Pfam:

PF00400

MIM:

139390

STRING:

9606.ENSP00000305260

String:

P62879

KEGG:

hsa:2783

SMR:

P62879

Uniprot:

P62879

FOR

ELISA Kit for Human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

CLIA Kit for Human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

Polyclonal Antibody for Human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

Monoclonal Antibody for Human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

Protein for Human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Distinct forms of the beta subunit of GTP-binding regulatory proteins identified by molecular cloning."
Fong H.K.W. , Amatruda T.T. III , Birren B.W. , Simon M.I.
Proc. Natl. Acad. Sci. U.S.A.84:3792-3796(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"A second form of the beta subunit of signal-transducing G proteins."
Gao B. , Gilman A.G. , Robishaw J.D.
Proc. Natl. Acad. Sci. U.S.A.84:6122-6125(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes."
Gloeckner G. , Scherer S. , Schattevoy R. , Boright A.P. , Weber J. , Tsui L.-C. , Rosenthal A.
Genome Res.8:1060-1073(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
Puhl H.L. III , Ikeda S.R. , Aronstam R.S.
Submitted (2002-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Placenta.
6.

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Pancreas.
tissue: Skin.
tissue: Uterus.
8.

Bienvenut W.V.
Submitted (2005-07) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-15 AND 58-78;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Melanoma.
9.

"G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production."
Niu J. , Profirovic J. , Pan H. , Vaiskunaite R. , Voyno-Yasenetskaya T.
Circ. Res.93:848-856(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ARHGEF18
10.

"Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit."
Waragai M. , Nagamitsu S. , Xu W. , Li Y.J. , Lin X. , Ashizawa T.
J. Neurosci. Res.83:1170-1178(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH ATXN10
11.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.

"The cationic region of Rhes mediates its interactions with specific Gbeta subunits."
Hill C. , Goddard A. , Ladds G. , Davey J.
Cell. Physiol. Biochem.23:1-8(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RASD2
13.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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