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Index > Protein center > GBP2(Gene name) > Human
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  • GBP2 (Gene name),
  • Interferon-induced guanylate-binding protein 2 (Protein name ),  GBP2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GBP2;
    Protein name:
    Interferon-induced guanylate-binding protein 2;
    Alternative:
    Guanine nucleotide-binding protein 2;GTP-binding protein 2(GBP-2;HuGBP-2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product.
    Subcellular Location:
    Cell membrane Lipid-anchor Cytoplasmic side
    Protein Attributes:
    Sequence length:
    591
    Sequence:
    50:
    MAPEINLPGP | MSLIDNTKGQ | LVVNPEALKI | LSAITQPVVV | VAIVGLYRTG | 
    100:
    KSYLMNKLAG | KKNGFSLGST | VKSHTKGIWM | WCVPHPKKPE | HTLVLLDTEG | 
    150:
    LGDIEKGDNE | NDSWIFALAI | LLSSTFVYNS | MGTINQQAMD | QLHYVTELTD | 
    200:
    RIKANSSPGN | NSVDDSADFV | SFFPAFVWTL | RDFTLELEVD | GEPITADDYL | 
    250:
    ELSLKLRKGT | DKKSKSFNDP | RLCIRKFFPK | RKCFVFDWPA | PKKYLAHLEQ | 
    300:
    LKEEELNPDF | IEQVAEFCSY | ILSHSNVKTL | SGGIPVNGPR | LESLVLTYVN | 
    350:
    AISSGDLPCM | ENAVLALAQI | ENSAAVEKAI | AHYEQQMGQK | VQLPTETLQE | 
    400:
    LLDLHRDSER | EAIEVFMKNS | FKDVDQMFQR | KLGAQLEARR | DDFCKQNSKA | 
    450:
    SSDCCMALLQ | DIFGPLEEDV | KQGTFSKPGG | YRLFTQKLQE | LKNKYYQVPR | 
    500:
    KGIQAKEVLK | KYLESKEDVA | DALLQTDQSL | SEKEKAIEVE | RIKAESAEAA | 
    550:
    KKMLEEIQKK | NEEMMEQKEK | SYQEHVKQLT | EKMERDRAQL | MAEQEKTLAL | 
    591:
    KLQEQERLLK | EGFENESKRL | QKDIWDIQMR | SKSLEPICNI | L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    MIM:
    KEGG:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Interferon-induced guanylate-binding protein 2
    ELISA Kit for Human Interferon-induced guanylate-binding protein 2
    ELISA Kit for Human Interferon-induced guanylate-binding protein 2
    CLIA Kit for Human Interferon-induced guanylate-binding protein 2
    CLIA Kit for Human Interferon-induced guanylate-binding protein 2
    CLIA Kit for Human Interferon-induced guanylate-binding protein 2
    Polyclonal Antibody for Human Interferon-induced guanylate-binding protein 2
    Polyclonal Antibody for Human Interferon-induced guanylate-binding protein 2
    Polyclonal Antibody for Human Interferon-induced guanylate-binding protein 2
    Monoclonal Antibody for Human Interferon-induced guanylate-binding protein 2
    Monoclonal Antibody for Human Interferon-induced guanylate-binding protein 2
    Monoclonal Antibody for Human Interferon-induced guanylate-binding protein 2
    Protein for Human Interferon-induced guanylate-binding protein 2
    Protein for Human Interferon-induced guanylate-binding protein 2
    Protein for Human Interferon-induced guanylate-binding protein 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP."
      Cheng Y.-S.E. , Patterson C.E. , Staeheli P.
      Mol. Cell. Biol.11:4717-4725(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ALA-285
    2. 2.
      Schwemmle M.
      Submitted (1991-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
      tissue: Foreskin.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS ALA-285 AND GLY-303
      tissue: Spinal cord.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS ALA-285 AND GLY-303
      tissue: Thymus.
    5. 5.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS ALA-285 AND GLY-303
    6. 6.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANTS ALA-285 AND GLY-303
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skin.
    9. 9.
      "GTPase properties of the interferon-induced human guanylate-binding protein 2."
      Neun R. , Richter M.F. , Staeheli P. , Schwemmle M.
      FEBS Lett.390:69-72(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GTPASE ACTIVITY
    10. 10.
      "Unique features of different members of the human guanylate-binding protein family."
      Tripal P. , Bauer M. , Naschberger E. , Mortinger T. , Hohenadl C. , Cornali E. , Thurau M. , Sturzl M.
      J. Interferon Cytokine Res.27:44-52(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INDUCTION
    11. 11.
      "Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner."
      Britzen-Laurent N. , Bauer M. , Berton V. , Fischer N. , Syguda A. , Reipschlager S. , Naschberger E. , Herrmann C. , Sturzl M.
      PLoS ONE5:E14246-E14246(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;ISOPRENYLATION AT CYS-588;SUBUNIT
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