Protein name:
Gamma-aminobutyric acid receptor subunit pi ;
Alternative:
GABA(A) receptor subunit pi ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and epsilon. A sixth class of subunit: Rho form homomeric GABA receptors that do not appear to coexist with GABA(A) receptor subunits but with GABA(C) receptor subunits. Subunit Pi can also bind this complex.
Function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
Subcellular Location:
Cell junction
synapse
postsynaptic cell membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MKRSLHLTFV | CLSLFSARMC | VQGNQFNIEV | SRSNKLSLPG | FENLTAGYNK |
100:
FLRPNFGGEP | VQIALTLDVA | SISSISESNM | DYTATIYLRQ | RWTDQRLVFE |
150:
GNKSFTLDAR | LVEFLWVPDT | YIVESKKSFL | HEVTVGNRLI | RLFSNGTVLY |
200:
ALRITTTVAC | NMDLSKYPMD | TQTCKLQLES | WGYDGNDVEF | SWLRGNDSVR |
250:
GLENLRLAQY | TIQQYFTSVT | RSQQETGNYT | RLVLQFELQR | NVLYFILETY |
300:
VPSTFLVVLS | WVSFWISLDS | VPARTCIGVT | TVLSMTTLMI | GSRTSLPNTN |
350:
CFIKAIDVYL | GICFSFVFGA | LLEYAVAHYS | SLQQMAAKDR | GKAKEVEEVN |
400:
ITNIINSSIS | SFKRKISFAS | IEISGDNVDY | SDLTMKTSDK | VKFVFRDKLG |
440:
RIVDYFTIQN | PSNVDRYSKL | LFPLIFMLAN | VFYWAYYMYF |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
Rat
ELISA Kit for Bovine Gamma-aminobutyric acid receptor subunit pi
ELISA Kit for Bovine Gamma-aminobutyric acid receptor subunit pi
ELISA Kit for Bovine Gamma-aminobutyric acid receptor subunit pi
ELISA Kit for Bovine Gamma-aminobutyric acid receptor subunit pi
CLIA Kit for Bovine Gamma-aminobutyric acid receptor subunit pi
CLIA Kit for Bovine Gamma-aminobutyric acid receptor subunit pi
CLIA Kit for Bovine Gamma-aminobutyric acid receptor subunit pi
CLIA Kit for Bovine Gamma-aminobutyric acid receptor subunit pi
Polyclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit pi
Polyclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit pi
Polyclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit pi
Polyclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit pi
Monoclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit pi
Monoclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit pi
Monoclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit pi
Monoclonal Antibody for Bovine Gamma-aminobutyric acid receptor subunit pi
Protein for Bovine Gamma-aminobutyric acid receptor subunit pi
Protein for Bovine Gamma-aminobutyric acid receptor subunit pi
Protein for Bovine Gamma-aminobutyric acid receptor subunit pi
Protein for Bovine Gamma-aminobutyric acid receptor subunit pi
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]