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Index > Protein center > GCM1(Gene name) > Human
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  • GCM1 (Gene name),
  • Chorion-specific transcription factor GCMa (Protein name ),  GCM1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GCM1(GCMA);
    Protein name:
    Chorion-specific transcription factor GCMa(hGCMa);
    Alternative:
    Glial cells missing homolog 1;GCM motif protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Transcription factor that is necessary for placental development. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    436
    Sequence:
    50:
    MEPDDFDSED | KEILSWDIND | VKLPQNVKKT | DWFQEWPDSY | AKHIYSSEDK | 
    100:
    NAQRHLSSWA | MRNTNNHNSR | ILKKSCLGVV | VCGRDCLAEE | GRKIYLRPAI | 
    150:
    CDKARQKQQR | KRCPNCDGPL | KLIPCRGHGG | FPVTNFWRHD | GRFIFFQSKG | 
    200:
    EHDHPKPETK | LEAEARRAMK | KVNTAPSSVS | LSLKGSTETR | SLPGETQSQG | 
    250:
    SLPLTWSFQE | GVQLPGSYSG | HLIANTPQQN | SLNDCFSFSK | SYGLGGITDL | 
    300:
    TDQTSTVDPM | KLYEKRKLSS | SRTYSSGDLL | PPSASGVYSD | HGDLQAWSKN | 
    350:
    AALGRNHLAD | NCYSNYPFPL | TSWPCSFSPS | QNSSEPFYQQ | LPLEPPAAKT | 
    400:
    GCPPLWPNPA | GNLYEEKVHV | DFNSYVQSPA | YHSPQEDPFL | FTYASHPHQQ | 
    436:
    YSLPSKSSKW | DFEEEMTYLG | LDHCNNDMLL | NLCPLR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    Pfam:
    UniGene:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human hGCMa
    ELISA Kit for Human hGCMa
    ELISA Kit for Human hGCMa
    CLIA Kit for Human hGCMa
    CLIA Kit for Human hGCMa
    CLIA Kit for Human hGCMa
    Polyclonal Antibody for Human hGCMa
    Polyclonal Antibody for Human hGCMa
    Polyclonal Antibody for Human hGCMa
    Monoclonal Antibody for Human hGCMa
    Monoclonal Antibody for Human hGCMa
    Monoclonal Antibody for Human hGCMa
    Protein for Human hGCMa
    Protein for Human hGCMa
    Protein for Human hGCMa

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    Precision
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    Linearity
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    References
    1. 1.
      "The gcm-motif: a novel DNA binding motif conserved in Drosophila and mammals."
      Akiyama Y. , Hosoya T. , Poole A.M. , Hotta Y.
      Proc. Natl. Acad. Sci. U.S.A.93:14912-14916(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Placenta.
    2. 2.
      "Structure of human GCMa cDNA and gene."
      Nishizawa M. , Ito S.
      Submitted (2000-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      tissue: Liver.
      tissue: Placenta.
    3. 3.
      "A GCM motif protein is involved in placenta-specific expression of human aromatase gene."
      Yamada K. , Ogawa H. , Honda S. , Harada N. , Okazaki T.
      J. Biol. Chem.274:32279-32286(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Placenta.
    4. 4.
      "Genomic organization, chromosomal localization, and the complete 22 kb DNA sequence of the human GCMa/GCM1, a placenta-specific transcription factor gene."
      Yamada K. , Ogawa H. , Tamiya G. , Ikeno M. , Morita M. , Asakawa S. , Shimizu N. , Okazaki T.
      Biochem. Biophys. Res. Commun.278:134-139(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    7. 7.
      "Ubiquitin-conjugating enzyme UBE2D2 is responsible for FBXW2 (F-box and WD repeat domain containing 2)-mediated human GCM1 (glial cell missing homolog 1) ubiquitination and degradation."
      Chiang M.H. , Chen L.F. , Chen H.
      Biol. Reprod.79:914-920(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POLYUBIQUITINATION
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