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Index > Protein center > Gdf6(Gene name) > Mouse
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  • Gdf6 (Gene name),
  • Growth/differentiation factor 6 (Protein name ),  GDF6_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Gdf6(Gdf-6;Gdf16);
    Protein name:
    Growth/differentiation factor 6(GDF-6);
    Alternative:
    Growth/differentiation factor 16;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked.
    Function:
    Required for normal formation of bones and joints in the limbs, skull, and axial skeleton. Play a key role in establishing boundaries between skeletal elements during development.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    454
    Sequence:
    50:
    MDTPRVLLWA | IFLISFLWDL | PGFQQASISS | SSSSSTELDS | TKDVGNRKEG | 
    100:
    KMQRTPQESA | EGRTPPEHGL | RQKDLRRRPP | GQHQGQEPPG | RGLRVVPHEY | 
    150:
    MLSIYKTYSI | AEKLGINASF | FQSSKSANTI | TSFVDRGLDD | LSHTPLRRQK | 
    200:
    YLFDVSTLSD | KEELVGAELR | LYRQAPPTPW | GLPARPLHLQ | LFPCLSPLLL | 
    250:
    DARTLDPQGP | TQAGWEVFDV | WQGLRPQPWK | QLCLELRAAW | GELDAGDTGA | 
    300:
    RARGPQQPPP | LDLRSLGFGR | RVRPPQERAL | LVVFTRSQRK | NLFTEMHEQL | 
    350:
    GSAEAAGAEG | SWPAPSGSPD | AGSWLPSPGR | RRRRTAFASR | HGKRHGKKSR | 
    400:
    LRCSRKPLHV | NFKELGWDDW | IIAPLEYEAY | HCEGVCDFPL | RSHLEPTNHA | 
    450:
    IIQTLMNSMD | PGSTPPSCCV | PTKLTPISIL | YIDAGNNVVY | KQYEDMVVES | 
    454:
    CGCR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse GDF-6
    ELISA Kit for Mouse GDF-6
    ELISA Kit for Mouse GDF-6
    ELISA Kit for Mouse GDF-6
    CLIA Kit for Mouse GDF-6
    CLIA Kit for Mouse GDF-6
    CLIA Kit for Mouse GDF-6
    CLIA Kit for Mouse GDF-6
    Polyclonal Antibody for Mouse GDF-6
    Polyclonal Antibody for Mouse GDF-6
    Polyclonal Antibody for Mouse GDF-6
    Polyclonal Antibody for Mouse GDF-6
    Monoclonal Antibody for Mouse GDF-6
    Monoclonal Antibody for Mouse GDF-6
    Monoclonal Antibody for Mouse GDF-6
    Monoclonal Antibody for Mouse GDF-6
    Protein for Mouse GDF-6
    Protein for Mouse GDF-6
    Protein for Mouse GDF-6
    Protein for Mouse GDF-6

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    Precision
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    Linearity
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    References
    1. 1.
      "Cloning of human GDF16 and functional assocatied analysis."
      Guo J.H.
      Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Kunming.
      tissue: Brain.
    2. 2.
      "Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily."
      Storm E.E. , Huynh T.V. , Copeland N.G. , Jenkins N.A. , Kingsley D.M. , Lee S.-J.
      Nature368:639-643(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 330-454
      strain: BALB/c.
      tissue: Liver.
    3. 3.
      "Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes."
      Settle S.H. Jr. , Rountree R.B. , Sinha A. , Thacker A. , Higgins K. , Kingsley D.M.
      Dev. Biol.254:116-130(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    4. 4.
      "Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses."
      Mazerbourg S. , Sangkuhl K. , Luo C.-W. , Sudo S. , Klein C. , Hsueh A.J.W.
      J. Biol. Chem.280:32122-32132(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION OF RECEPTORS
    5. 5.
      "Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies."
      Asai-Coakwell M. , March L. , Dai X.H. , Duval M. , Lopez I. , French C.R. , Famulski J. , De Baere E. , Francis P.J. , Sundaresan P. , Sauve Y. , Koenekoop R.K. , Berry F.B. , Allison W.T. , Waskiewicz A.J. , Lehmann O.J.
      Hum. Mol. Genet.22:1432-1442(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
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