Gene name:
Gdf6 (Gdf-6;Gdf16) ;
Protein name:
Growth/differentiation factor 6 (GDF-6) ;
Alternative:
Growth/differentiation factor 16 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer; disulfide-linked.
Function:
Required for normal formation of bones and joints in the limbs, skull, and axial skeleton. Play a key role in establishing boundaries between skeletal elements during development.
Subcellular Location:
Secreted
Protein Attributes:
50:
MDTPRVLLWA | IFLISFLWDL | PGFQQASISS | SSSSSTELDS | TKDVGNRKEG |
100:
KMQRTPQESA | EGRTPPEHGL | RQKDLRRRPP | GQHQGQEPPG | RGLRVVPHEY |
150:
MLSIYKTYSI | AEKLGINASF | FQSSKSANTI | TSFVDRGLDD | LSHTPLRRQK |
200:
YLFDVSTLSD | KEELVGAELR | LYRQAPPTPW | GLPARPLHLQ | LFPCLSPLLL |
250:
DARTLDPQGP | TQAGWEVFDV | WQGLRPQPWK | QLCLELRAAW | GELDAGDTGA |
300:
RARGPQQPPP | LDLRSLGFGR | RVRPPQERAL | LVVFTRSQRK | NLFTEMHEQL |
350:
GSAEAAGAEG | SWPAPSGSPD | AGSWLPSPGR | RRRRTAFASR | HGKRHGKKSR |
400:
LRCSRKPLHV | NFKELGWDDW | IIAPLEYEAY | HCEGVCDFPL | RSHLEPTNHA |
450:
IIQTLMNSMD | PGSTPPSCCV | PTKLTPISIL | YIDAGNNVVY | KQYEDMVVES |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Rat
Mouse
ELISA Kit for Mouse GDF-6
ELISA Kit for Mouse GDF-6
ELISA Kit for Mouse GDF-6
ELISA Kit for Mouse GDF-6
Polyclonal Antibody for Mouse GDF-6
Polyclonal Antibody for Mouse GDF-6
Polyclonal Antibody for Mouse GDF-6
Polyclonal Antibody for Mouse GDF-6
Monoclonal Antibody for Mouse GDF-6
Monoclonal Antibody for Mouse GDF-6
Monoclonal Antibody for Mouse GDF-6
Monoclonal Antibody for Mouse GDF-6
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Cloning of human GDF16 and functional assocatied analysis."
Guo J.H.
Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Kunming .
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 330-454
strain :
BALB/c .
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;IDENTIFICATION OF RECEPTORS
5.
"Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies."
Asai-Coakwell M.
,
March L.
,
Dai X.H.
,
Duval M.
,
Lopez I.
,
French C.R.
,
Famulski J.
,
De Baere E.
,
Francis P.J.
,
Sundaresan P.
,
Sauve Y.
,
Koenekoop R.K.
,
Berry F.B.
,
Allison W.T.
,
Waskiewicz A.J.
,
Lehmann O.J.
Hum. Mol. Genet.22:1432-1442(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;DISRUPTION PHENOTYPE
6.
"BMP signaling controls muscle mass."
Sartori R.
,
Schirwis E.
,
Blaauw B.
,
Bortolanza S.
,
Zhao J.
,
Enzo E.
,
Stantzou A.
,
Mouisel E.
,
Toniolo L.
,
Ferry A.
,
Stricker S.
,
Goldberg A.L.
,
Dupont S.
,
Piccolo S.
,
Amthor H.
,
Sandri M.
Nat. Genet.45:1309-1318(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INDUCTION