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Index > Protein center > MSTN(Gene name) > Bovine
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  • MSTN (Gene name),
  • Growth/differentiation factor 8 (Protein name ),  GDF8_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    MSTN(GDF8;MH);
    Protein name:
    Growth/differentiation factor 8(GDF-8);
    Alternative:
    Myostatin;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked (By similarity). Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FST3.
    Function:
    Acts specifically as a negative regulator of skeletal muscle growth.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    375
    Sequence:
    50:
    MQKLQISVYI | YLFMLIVAGP | VDLNENSEQK | ENVEKEGLCN | ACLWRENTTS | 
    100:
    SRLEAIKIQI | LSKLRLETAP | NISKDAIRQL | LPKAPPLLEL | IDQFDVQRDA | 
    150:
    SSDGSLEDDD | YHARTETVIT | MPTESDLLTQ | VEGKPKCCFF | KFSSKIQYNK | 
    200:
    LVKAQLWIYL | RPVKTPATVF | VQILRLIKPM | KDGTRYTGIR | SLKLDMNPGT | 
    250:
    GIWQSIDVKT | VLQNWLKQPE | SNLGIEIKAL | DENGHDLAVT | FPEPGEDGLT | 
    300:
    PFLEVKVTDT | PKRSRRDFGL | DCDEHSTESR | CCRYPLTVDF | EAFGWDWIIA | 
    350:
    PKRYKANYCS | GECEFVFLQK | YPHTHLVHQA | NPRGSAGPCC | TPTKMSPINM | 
    375:
    LYFNGEGQII | YGKIPAMVVD | RCGCS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine GDF-8
    Cat.:
    E1653h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine GDF-8
    Cat.:
    E1653m
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    96T
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    ELISA Kit for Bovine GDF-8
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    E1653r
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    ELISA Kit for Bovine GDF-8
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    E1653c
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    96T
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    ELISA Kit for Bovine GDF-8
    Cat.:
    E1653d
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    96T
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    ELISA Kit for Bovine GDF-8
    Cat.:
    E1653p
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    96T
    ELISA Kit for Bovine GDF-8
    Cat.:
    E1653b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine GDF-8
    Cat.:
    U1653b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine GDF-8
    Cat.:
    U1653d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine GDF-8
    Cat.:
    U1653p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine GDF-8
    Cat.:
    U1653c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine GDF-8
    Cat.:
    U1653r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine GDF-8
    Cat.:
    U1653m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine GDF-8
    Cat.:
    U1653h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Bovine GDF-8
    Polyclonal Antibody for Bovine GDF-8
    Cat.:
    P1653Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine GDF-8
    Polyclonal Antibody for Bovine GDF-8
    Cat.:
    P1653Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine GDF-8
    Cat.:
    P1653Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine GDF-8
    Polyclonal Antibody for Bovine GDF-8
    Monoclonal Antibody for Bovine GDF-8
    Monoclonal Antibody for Bovine GDF-8
    Monoclonal Antibody for Bovine GDF-8
    Monoclonal Antibody for Bovine GDF-8
    Monoclonal Antibody for Bovine GDF-8
    Monoclonal Antibody for Bovine GDF-8
    Monoclonal Antibody for Bovine GDF-8
    Protein for Bovine GDF-8
    Protein for Bovine GDF-8
    Protein for Bovine GDF-8
    Protein for Bovine GDF-8
    Protein for Bovine GDF-8
    Protein for Bovine GDF-8
    Protein for Bovine GDF-8

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    References
    1. 1.
      "Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle."
      Kambadur R. , Sharma M. , Smith T.P.L. , Bass J.J.
      Genome Res.7:910-916(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT MH TYR-313
      strain: Friesian.
      tissue: Embryo.
      tissue: Muscle.
    2. 2.
      "Double muscling in cattle due to mutations in the myostatin gene."
      McPherron A.C. , Lee S.-J.
      Proc. Natl. Acad. Sci. U.S.A.94:12457-12461(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS MH LEU-94 AND TYR-313
      strain: Holstein.
      tissue: Skeletal muscle.
    3. 3.
      "Genomic organization and neonatal expression of the bovine myostatin gene."
      Jeanplong F. , Sharma M. , Somers W.G. , Bass J.J. , Kambadur R.
      Mol. Cell. Biochem.220:31-37(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Nucleotide sequence of myostatin gene and its developmental expression in skeletal muscles of Japanese Black cattle."
      Shibata M. , Ohshima K. , Kojima T. , Muramoto T. , Matsumoto K. , Komatsu M. , Aikawa K. , Fujimura S. , Kadowaki M.
      Anim. Sci. J.74:383-390(2003)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: Japanese black.
    5. 5.
      "Characterization of the bovine myostatin gene in Korean native cattle."
      Kim D.Y. , Yoo S.L. , Sang B.C. , Cho K.W. , Lee J.H.
      Submitted (2002-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Korean.
    6. 6.
      "Nucleotide sequence determination and molecular characterization of GDF-8 gene from Beefmaster cattle."
      De la Rosa X.F. , Sifuentes A.M.
      Submitted (2004-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: Beefmaster.
    7. 7.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Basal ganglia.
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