Protein name:
Growth/differentiation factor 8(GDF-8);
Alternative:
Myostatin;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Sub Unit:
Homodimer; disulfide-linked (By similarity). Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FST3.
Function:
Acts specifically as a negative regulator of skeletal muscle growth.
Subcellular Location:
Secreted
Protein Attributes:
50:
MQRLQICVYI | YLFVLIVAGP | VDLSENSEQK | ENVEKEGLCN | ACMWRQNTKS |
100:
SRIEAIKIQI | LSKLRLETAP | NISRDAVRQL | LPRAPPLREL | IDQYDVQRDD |
150:
SSDGSLEDDD | YHATTETVIA | MPAETDLLMQ | VEGKPKCCFF | KFSSKIQYNK |
200:
VVKAQLWIYL | RPVKTPTTVF | VQILRLIKPM | KDGTRYTGIR | SLKLDMNPGT |
250:
GIWQSIDVKT | VLQNWLKQPE | SNLGIEIKAL | DENGHDLAVT | FPGPGEDGLN |
300:
PFLEVKVTDT | PKRSRRDFGL | DCDEHSTESR | CCRYPLTVDF | EAFGWDWIIA |
350:
PKRYKANYCS | GECEFVFLQK | YPHTHLVHQA | NPRGSAGPCC | TPTKMSPINM |
375:
LYFNGKEQII | YGKIPAMVVD | RCGCS

Vaild Sequence:
Related Databases
Uniprot:
FOR
Polyclonal Antibody for Dog GDF-8
Polyclonal Antibody for Dog GDF-8
Polyclonal Antibody for Dog GDF-8
Polyclonal Antibody for Dog GDF-8
Polyclonal Antibody for Dog GDF-8
Polyclonal Antibody for Dog GDF-8
Polyclonal Antibody for Dog GDF-8
Monoclonal Antibody for Dog GDF-8
Monoclonal Antibody for Dog GDF-8
Monoclonal Antibody for Dog GDF-8
Monoclonal Antibody for Dog GDF-8
Monoclonal Antibody for Dog GDF-8
Monoclonal Antibody for Dog GDF-8
Monoclonal Antibody for Dog GDF-8

R&D Technical Data
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Precision
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Recovery
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Linearity
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References
-
1.
"Cloning and characterization of canine myostatin (MSTN)."
Perkins K.J.
,
Khurana T.S.
Submitted (2003-08) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [MRNA]