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Index > Protein center > Mstn(Gene name) > Mouse
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  • Mstn (Gene name),
  • Growth/differentiation factor 8 (Protein name ),  GDF8_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Mstn(Gdf8);
    Protein name:
    Growth/differentiation factor 8(GDF-8);
    Alternative:
    Myostatin;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked (By similarity). Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FST3.
    Function:
    Acts specifically as a negative regulator of skeletal muscle growth.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    376
    Sequence:
    50:
    MMQKLQMYVY | IYLFMLIAAG | PVDLNEGSER | EENVEKEGLC | NACAWRQNTR | 
    100:
    YSRIEAIKIQ | ILSKLRLETA | PNISKDAIRQ | LLPRAPPLRE | LIDQYDVQRD | 
    150:
    DSSDGSLEDD | DYHATTETII | TMPTESDFLM | QADGKPKCCF | FKFSSKIQYN | 
    200:
    KVVKAQLWIY | LRPVKTPTTV | FVQILRLIKP | MKDGTRYTGI | RSLKLDMSPG | 
    250:
    TGIWQSIDVK | TVLQNWLKQP | ESNLGIEIKA | LDENGHDLAV | TFPGPGEDGL | 
    300:
    NPFLEVKVTD | TPKRSRRDFG | LDCDEHSTES | RCCRYPLTVD | FEAFGWDWII | 
    350:
    APKRYKANYC | SGECEFVFLQ | KYPHTHLVHQ | ANPRGSAGPC | CTPTKMSPIN | 
    376:
    MLYFNGKEQI | IYGKIPAMVV | DRCGCS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse GDF-8
    Cat.:
    E1653h
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    Packing:
    96T
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    ELISA Kit for Mouse GDF-8
    Cat.:
    E1653m
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    96T
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    ELISA Kit for Mouse GDF-8
    Cat.:
    E1653r
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    96T
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    ELISA Kit for Mouse GDF-8
    Cat.:
    E1653c
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    96T
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    ELISA Kit for Mouse GDF-8
    Cat.:
    E1653d
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    96T
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    ELISA Kit for Mouse GDF-8
    Cat.:
    E1653p
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse GDF-8
    Cat.:
    E1653b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse GDF-8
    Cat.:
    U1653b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse GDF-8
    Cat.:
    U1653d
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse GDF-8
    Cat.:
    U1653p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse GDF-8
    Cat.:
    U1653c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse GDF-8
    Cat.:
    U1653r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse GDF-8
    Cat.:
    U1653m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse GDF-8
    Cat.:
    U1653h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Mouse GDF-8
    Polyclonal Antibody for Mouse GDF-8
    Cat.:
    P1653Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse GDF-8
    Polyclonal Antibody for Mouse GDF-8
    Cat.:
    P1653Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse GDF-8
    Cat.:
    P1653Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse GDF-8
    Polyclonal Antibody for Mouse GDF-8
    Monoclonal Antibody for Mouse GDF-8
    Monoclonal Antibody for Mouse GDF-8
    Monoclonal Antibody for Mouse GDF-8
    Monoclonal Antibody for Mouse GDF-8
    Monoclonal Antibody for Mouse GDF-8
    Monoclonal Antibody for Mouse GDF-8
    Monoclonal Antibody for Mouse GDF-8
    Protein for Mouse GDF-8
    Protein for Mouse GDF-8
    Protein for Mouse GDF-8
    Protein for Mouse GDF-8
    Protein for Mouse GDF-8
    Protein for Mouse GDF-8
    Protein for Mouse GDF-8

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    References
    1. 1.
      "Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member."
      McPherron A.C. , Lawler A.M. , Lee S.-J.
      Nature387:83-90(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: CD-1.
      tissue: Skeletal muscle.
    2. 2.
      "Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains."
      Hill J.J. , Qiu Y. , Hewick R.M. , Wolfman N.M.
      Mol. Endocrinol.17:1144-1154(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH WFIKKN2
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
    4. 4.
      "The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding."
      Cash J.N. , Rejon C.A. , McPherron A.C. , Bernard D.J. , Thompson T.B.
      EMBO J.28:2662-2676(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS) OF 268-376 IN COMPLEX WITH HUMAN FOLLISTATIN;HEPARIN-BINDING;DISULFIDE BONDS
    5. 5.
      "Structure of myostatin.follistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding."
      Cash J.N. , Angerman E.B. , Kattamuri C. , Nolan K. , Zhao H. , Sidis Y. , Keutmann H.T. , Thompson T.B.
      J. Biol. Chem.287:1043-1053(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 268-376 IN COMPLEX WITH HUMAN FSTL3;DISULFIDE BONDS
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