Gfra1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comGfra1 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Gfra1(Gene name) > Rat

Gfra1 (Gene name),

GDNF family receptor alpha-1 (Protein name ), GFRA1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Gfra1(Gdnfra;Retl1;Trnr1);

Protein name:

GDNF family receptor alpha-1(GDNF receptor alpha-1;GDNFR-alpha-1;GFR-alpha-1);

Alternative:

TGF-beta-related neurotrophic factor receptor 1;RET ligand 1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.

Function:

Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

Subcellular Location:

Cell membrane Lipid-anchor GPI-anchor

Protein Attributes:

Sequence length:

468

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

468:

LMLTALAALL | SVSLAETS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q62997

KEGG:

rno:25454

UniGene:

Rn.88489

SMR:

Q62997

Pfam:

PF02351

Uniprot:

Q62997

FOR

ELISA Kit for Rat GDNF receptor alpha-1

Cat.:

E2753h

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Packing:

96T

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ELISA Kit for Rat GDNF receptor alpha-1

Cat.:

E2753r

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96T

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ELISA Kit for Rat GDNF receptor alpha-1

Cat.:

E2753m

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MSDS:

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Packing:

96T

ELISA Kit for Rat GDNF receptor alpha-1

Cat.:

E2753c

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MSDS:

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Packing:

96T

CLIA Kit for Rat GDNF receptor alpha-1

Cat.:

U2753c

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MSDS:

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Packing:

96T

CLIA Kit for Rat GDNF receptor alpha-1

Cat.:

U2753m

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MSDS:

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Packing:

96T

CLIA Kit for Rat GDNF receptor alpha-1

Cat.:

U2753r

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat GDNF receptor alpha-1

Cat.:

U2753h

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Looking for manual.

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96T

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Polyclonal Antibody for Rat GDNF receptor alpha-1

Cat.:

P2753Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat GDNF receptor alpha-1

Cat.:

P2753Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat GDNF receptor alpha-1

Cat.:

P2753Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat GDNF receptor alpha-1

Protein for Rat GDNF receptor alpha-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF."
Jing S. , Wen D. , Yu Y. , Holst P.L. , Luo Y. , Fang M. , Tamir R. , Antonio L. , Hu Z. , Cupples R. , Louis J.-C. , Hu S. , Altrock B.W. , Fox G.M.
Cell85:1113-1124(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Retina.
2.

"Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins."
Sanicola M. , Hession C.A. , Worley D.S. , Carmillo P. , Ehrenfels C. , Walus L. , Robinson S. , Jaworski G. , Wei H. , Tizard R. , Whitty A. , Pepinsky R.B. , Cate R.L.
Proc. Natl. Acad. Sci. U.S.A.94:6238-6243(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Wistar.
tissue: Kidney.
3.

"Characterization of a multicomponent receptor for GDNF."
Treanor J.J.S. , Googman L. , de Sauvage F. , Stone D.M. , Poulsen K.T. , Beck C.D. , Gray C. , Armanini M.P. , Pollock R.A. , Hefti F. , Phillips H.S. , Goddard A. , Moore M.W. , Buj-Bello A. , Davies A.M. , Asai N. , Takahashi M. , Vandlen R. , more...
Nature382:80-83(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Expression of the GDNF family members and their receptors in the mature rat cochlea."
Stoever T. , Gong T.-W.L. , Cho Y. , Altschuler R.A. , Lomax M.I.
Brain Res. Mol. Brain Res.76:25-35(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
5.

"The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation."
Leppanen V.M. , Bespalov M.M. , Runeberg-Roos P. , Puurand U. , Merits A. , Saarma M. , Goldman A.
EMBO J.23:1452-1462(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 239-346;DISULFIDE BONDS

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