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Index > Protein center > GLUL(Gene name) > Human
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  • GLUL (Gene name),
  • Glutamine synthetase (Protein name ),  GLNA_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GLUL(GLNS);
    Protein name:
    Glutamine synthetase(GS);
    Alternative:
    Glutamate--ammonia ligase;4.1.1.15;Glutamate decarboxylase);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homooctamer and homotetramer. Interacts with PALMD.
    Function:
    This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts.
    Subcellular Location:
    Cytoplasm Mitochondrion
    Protein Attributes:
    Sequence length:
    373
    Sequence:
    50:
    MTTSASSHLN | KGIKQVYMSL | PQGEKVQAMY | IWIDGTGEGL | RCKTRTLDSE | 
    100:
    PKCVEELPEW | NFDGSSTLQS | EGSNSDMYLV | PAAMFRDPFR | KDPNKLVLCE | 
    150:
    VFKYNRRPAE | TNLRHTCKRI | MDMVSNQHPW | FGMEQEYTLM | GTDGHPFGWP | 
    200:
    SNGFPGPQGP | YYCGVGADRA | YGRDIVEAHY | RACLYAGVKI | AGTNAEVMPA | 
    250:
    QWEFQIGPCE | GISMGDHLWV | ARFILHRVCE | DFGVIATFDP | KPIPGNWNGA | 
    300:
    GCHTNFSTKA | MREENGLKYI | EEAIEKLSKR | HQYHIRAYDP | KGGLDNARRL | 
    350:
    TGFHETSNIN | DFSAGVANRS | ASIRIPRTVG | QEKKGYFEDR | RPSANCDPFS | 
    373:
    VTEALIRTCL | LNETGDEPFQ | YKN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    MIM:
    SMR:
    KEGG:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human GS
    Cat.:
    E0162h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human GS
    Cat.:
    E0162b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human GS
    Cat.:
    E0162m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human GS
    Cat.:
    E0162r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human GS
    Cat.:
    E0162p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human GS
    Cat.:
    E0162c
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human GS
    Cat.:
    E0162d
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human GS
    Cat.:
    U0162c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human GS
    Cat.:
    U0162r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human GS
    Cat.:
    U0162b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human GS
    Cat.:
    U0162h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human GS
    Cat.:
    U0162m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human GS
    Cat.:
    U0162p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human GS
    Cat.:
    U0162d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human GS
    Polyclonal Antibody for Human GS
    Cat.:
    P0162Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human GS
    Cat.:
    P0162Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human GS
    Polyclonal Antibody for Human GS
    Polyclonal Antibody for Human GS
    Cat.:
    P0162Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human GS
    Monoclonal Antibody for Human GS
    Monoclonal Antibody for Human GS
    Monoclonal Antibody for Human GS
    Monoclonal Antibody for Human GS
    Monoclonal Antibody for Human GS
    Monoclonal Antibody for Human GS
    Monoclonal Antibody for Human GS
    Protein for Human GS
    Protein for Human GS
    Protein for Human GS
    Protein for Human GS
    Protein for Human GS
    Protein for Human GS
    Protein for Human GS

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    References
    1. 1.
      "Sequence of a human glutamine synthetase cDNA."
      Gibbs C.S. , Campbell K.E. , Wilson R.H.
      Nucleic Acids Res.15:6293-6293(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    3. 3.
      "Overexpression of glutamine synthetase in human primary liver cancer."
      Christa L. , Simon M.T. , Flinois J.P. , Gebhardt R. , Brechot C. , Lasserre C.
      Gastroenterology106:1312-1320(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    4. 4.
      Haberle J. , Koch H.G.
      Submitted (2003-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Retina.
    6. 6.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
      tissue: Colon.
      tissue: Eye.
      tissue: Muscle.
      tissue: Testis.
    8. 8.
      "Glutamine synthetase isolated from human brain: octameric structure and homology of partial primary structure with human liver glutamine synthetase."
      Boksha I.S. , Schonfeld H.J. , Langen H. , Muller F. , Tereshkina E.B. , Burbaeva G.S.H.
      Biochemistry (Mosc.)67:1012-1020(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
    9. 9.
      "Glutamine synthetase is essential for proliferation of fetal skin fibroblasts."
      Vermeulen T. , Goerg B. , Vogl T. , Wolf M. , Varga G. , Toutain A. , Paul R. , Schliess F. , Haeussinger D. , Haeberle J.
      Arch. Biochem. Biophys.478:96-102(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DEVELOPMENTAL STAGE
    10. 10.
      "Wnt and steroid pathways control glutamate signalling by regulating glutamine synthetase activity in osteoblastic cells."
      Olkku A. , Mahonen A.
      Bone43:483-493(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
    11. 11.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT THR-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CSGD CYS-324 AND CYS-341;CHARACTERIZATION OF VARIANTS CSGD CYS-324 AND CYS-341
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