Protein name:
    Glutaredoxin-2, mitochondrial ;
    
    Alternative:
    
    
    
 
    Organism:
        
        
        
        
        
        
    
        Bovine  (Bos taurus).  
    
 
General Annotation
    Sub Unit:
    Monomer; active form. Homodimer; inactive form. The homodimer is probably linked by 1 2Fe-2S cluster.
    
 
    Function:
    Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Mitochondrion 
     
  
    
 
    
    Protein Attributes:
    
    50:
    MYWRRAALVG |  TRLIPVRSSS |  AGRLEGPAGI |  SGSGMGNSTS |  SSLGNAATAP |  
    
 
    100:
    VNQIQETISN |  NCVVIFSKTS |  CSYCTMAKNL |  FHDMNVNYKV |  VELDMLEYGS |  
    
 
    150:
    QFQDALHKMT |  GERTVPRIFV |  NGTFIGGATD |  THRLHKEGKL |  LPLVHQCHLK |  
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Human
         
        
        Mouse
         
        
        Bovine
         
        
        Rat
         
        
     
    
        ELISA Kit for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
    
    
 
    
        Protein for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
    
    
 
    
        Protein for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
    
    
 
    
        Protein for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
    
    
 
    
        Protein for Bovine Glutaredoxin-2, mitochondrial
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
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    Precision
    
    
    
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    Recovery
    
    
    
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    Linearity
    
    
    
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    References
    
    
        
            
        
            
                1.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 
                    
                    
                    strain :
                    
Crossbred X Angus . tissue :
                    
Liver .