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Index > Protein center > SHMT1(Gene name) > Human
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  • SHMT1 (Gene name),
  • Serine hydroxymethyltransferase, cytosolic (Protein name ),  GLYC_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SHMT1;
    Protein name:
    Serine hydroxymethyltransferase, cytosolic(SHMT);
    Alternative:
    Serine methylase;Glycine hydroxymethyltransferase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Interconversion of serine and glycine.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    483
    Sequence:
    50:
    MTMPVNGAHK | DADLWSSHDK | MLAQPLKDSD | VEVYNIIKKE | SNRQRVGLEL | 
    100:
    IASENFASRA | VLEALGSCLN | NKYSEGYPGQ | RYYGGTEFID | ELETLCQKRA | 
    150:
    LQAYKLDPQC | WGVNVQPYSG | SPANFAVYTA | LVEPHGRIMG | LDLPDGGHLT | 
    200:
    HGFMTDKKKI | SATSIFFESM | PYKVNPDTGY | INYDQLEENA | RLFHPKLIIA | 
    250:
    GTSCYSRNLE | YARLRKIADE | NGAYLMADMA | HISGLVAAGV | VPSPFEHCHV | 
    300:
    VTTTTHKTLR | GCRAGMIFYR | KGVKSVDPKT | GKEILYNLES | LINSAVFPGL | 
    350:
    QGGPHNHAIA | GVAVALKQAM | TLEFKVYQHQ | VVANCRALSE | ALTELGYKIV | 
    400:
    TGGSDNHLIL | VDLRSKGTDG | GRAEKVLEAC | SIACNKNTCP | GDRSALRPSG | 
    450:
    LRLGTPALTS | RGLLEKDFQK | VAHFIHRGIE | LTLQIQSDTG | VRATLKEFKE | 
    483:
    RLAGDKYQAA | VQALREEVES | FASLFPLPGL | PDF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    String:
    Pfam:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human SHMT
    ELISA Kit for Human SHMT
    ELISA Kit for Human SHMT
    ELISA Kit for Human SHMT
    CLIA Kit for Human SHMT
    CLIA Kit for Human SHMT
    CLIA Kit for Human SHMT
    CLIA Kit for Human SHMT
    Polyclonal Antibody for Human SHMT
    Polyclonal Antibody for Human SHMT
    Polyclonal Antibody for Human SHMT
    Polyclonal Antibody for Human SHMT
    Monoclonal Antibody for Human SHMT
    Monoclonal Antibody for Human SHMT
    Monoclonal Antibody for Human SHMT
    Monoclonal Antibody for Human SHMT
    Protein for Human SHMT
    Protein for Human SHMT
    Protein for Human SHMT
    Protein for Human SHMT

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization."
      Garrow T.A. , Brenner A.A. , Whitehead M.V. , Chen X.-N. , Duncan R.G. , Korenberg J.R. , Shane B.
      J. Biol. Chem.268:11910-11916(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      Xu L. , Mangum J.H. , Robertson D.L.
      Submitted (1994-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    3. 3.
      "Isolation and characterisation of human genomic sequences encoding cytosolic serine hydroxymethyltransferase."
      Chave K.J. , Snell K. , Sanders P.G.
      Biochem. Soc. Trans.25:53-53(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Mammary gland.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      tissue: Liver.
    5. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT PHE-474
    6. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT PHE-474
      tissue: Bone marrow.
      tissue: Lymph.
      tissue: Testis.
    7. 8.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-271 (ISOFORM 2);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 10.
      "The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy."
      Renwick S.B. , Snell K. , Baumann U.
      Structure6:1105-1116(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.65 ANGSTROMS) OF 11-480
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