Protein name:
Glucocorticoid modulatory element-binding protein 2 (GMEB-2) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer, and heterodimer of GMEB1 and GMEB2. Interacts with the glucocorticoid receptor (NR3C1). May interact with CREB-binding protein (CBP).
Function:
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter.
Subcellular Location:
Nucleus
Cytoplasm
May be also cytoplasmic.
Protein Attributes:
50:
MATPDVSVHM | EEVVVVTTPD | TAVDGSGVEE | VKTVLVTTNL | APHGGDLTED |
100:
NMETENAAAA | AAAAFTASSQ | LKEAVLVKMA | EEGENLEAEI | VYPITCGDSR |
150:
ANLIWRKFVC | PGINVKCVQY | DEHVISPKEF | VHLAGKSTLK | DWKRAIRMNG |
200:
IMLRKIMDSG | ELDFYQHDKV | CSNTCRSTKI | DLSGARVSLS | SPTSTEYIPL |
250:
TPAAADVNGS | PATITIETCE | DPGDWTTTIG | DDTFAFWRGL | KDAGLLDEVI |
300:
QEFQQELEET | MKGLQQRVQD | PPLQLRDAVL | LNNIVQNFGM | LDLVKKVLAS |
350:
HKCQMDRSRE | QYARDLAALE | QQCDEHRRRA | KELKHKSQHL | SNVLMTLTPV |
400:
PLPSPMKRPR | LARATSGPAA | MASQVLTQSA | QIALSPGMPV | SQLTSVPLGK |
450:
VVSTLPSTVL | GKGSPQAAPA | SSPASPLLGG | YTVLASSGST | FPNAVEIHPD |
500:
TSSLTVLSTA | AMQDGSTVLK | VVSPLQLLTL | PGLGPTLQNV | AQASPAGSTI |
530:
VTMPTATATG | PEEHTATIEV | AAVAEDHEQK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Mouse GMEB-2
ELISA Kit for Mouse GMEB-2
ELISA Kit for Mouse GMEB-2
CLIA Kit for Mouse GMEB-2
CLIA Kit for Mouse GMEB-2
CLIA Kit for Mouse GMEB-2
Polyclonal Antibody for Mouse GMEB-2
Polyclonal Antibody for Mouse GMEB-2
Polyclonal Antibody for Mouse GMEB-2
Monoclonal Antibody for Mouse GMEB-2
Monoclonal Antibody for Mouse GMEB-2
Monoclonal Antibody for Mouse GMEB-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
strain :
FVB/N .
tissue :
Brain .
tissue :
Mammary tumor .