Gorasp1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comGorasp1 ELISA Kit for Rat(Rattus norvegicus)

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Gorasp1 (Gene name),

Golgi reassembly-stacking protein 1 (Protein name ), GORS1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Gorasp1(Grasp65);

Protein name:

Golgi reassembly-stacking protein 1;

Alternative:

Golgi reassembly-stacking protein of 65 kDa(GRASP65);Golgi peripheral membrane protein p65;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer. Forms higher order oligomers under interphase but not mitotic conditions. Dimers of the protein on one membrane might be able to interact with dimers on another and so stack cisternae. Interacts with the C-terminus of GM130 under both mitotic and non-mitotic conditions. The interaction is critical for the correct targeting of both proteins to the cis-Golgi. The complex binds to the vesicle docking protein p115.

Function:

Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity: its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GM130, the docking of transport vesicles with the Golgi membranes.

Subcellular Location:

Golgi apparatus cis-Golgi network membrane Peripheral membrane protein Cytoplasmic side Undergoes rapid exchange with the cytosol.

Protein Attributes:

Sequence length:

451

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

451:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O35254

UniGene:

Rn.144458

Pfam:

PF04495

Uniprot:

O35254

FOR

ELISA Kit for Rat Golgi reassembly-stacking protein 1

CLIA Kit for Rat Golgi reassembly-stacking protein 1

Polyclonal Antibody for Rat Golgi reassembly-stacking protein 1

Monoclonal Antibody for Rat Golgi reassembly-stacking protein 1

Protein for Rat Golgi reassembly-stacking protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"GRASP65, a protein involved in the stacking of Golgi cisternae."
Barr F.A. , Puype M. , Vandekerckhove J. , Warren G.
Cell91:253-262(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH GM130;PHOSPHORYLATION;MYRISTOYLATION AT GLY-2
strain: Sprague-Dawley.
tissue: Liver.
2.

Barr F.A.
Submitted (1999-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
3.

"Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus."
Barr F.A. , Preisinger C. , Kopajtich R. , Koerner R.
J. Cell Biol.155:885-891(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TMED2 AND TMED3
4.

"Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis."
Lane J.D. , Lucocq J. , Pryde J. , Barr F.A. , Woodman P.G. , Allan V.J. , Lowe M.
J. Cell Biol.156:495-509(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CASPASE-MEDIATED CLEAVAGE;MUTAGENESIS OF ASP-320; ASP-375 AND ASP-393
5.

"Mapping the interaction between GRASP65 and GM130, components of a protein complex involved in the stacking of Golgi cisternae."
Barr F.A. , Nakamura N. , Warren G.
EMBO J.17:3258-3268(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GM130
6.

"Fragmentation and dispersal of the pericentriolar Golgi complex is required for entry into mitosis in mammalian cells."
Suetterlin C. , Hsu P. , Mallabiabarrena A. , Malhotra V.
Cell109:359-369(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN GOLGI FRAGMENTATION

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