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Index > Protein center > Gpr119(Gene name) > Mouse
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  • Gpr119 (Gene name),
  • Glucose-dependent insulinotropic receptor (Protein name ),  GP119_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Gpr119;
    Protein name:
    Glucose-dependent insulinotropic receptor;
    Alternative:
    G-protein coupled receptor 119;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    335
    Sequence:
    50:
    MESSFSFGVI | LAVLTILIIA | VNALVVVAML | LSIYKNDGVG | LCFTLNLAVA | 
    100:
    DTLIGVAISG | LVTDQLSSSA | QHTQKTLCSL | RMAFVTSSAA | ASVLTVMLIA | 
    150:
    FDRYLAIKQP | LRYFQIMNGL | VAGACIAGLW | LVSYLIGFLP | LGVSIFQQTT | 
    200:
    YHGPCSFFAV | FHPRFVLTLS | CAGFFPAVLL | FVFFYCDMLK | IASVHSQQIR | 
    250:
    KMEHAGAMAG | AYRPPRSVND | FKAVRTIAVL | IGSFTLSWSP | FLITSIVQVA | 
    300:
    CHKCCLYQVL | EKYLWLLGVG | NSLLNPLIYA | YWQREVRQQL | YHMALGVKKF | 
    335:
    FTSILLLLPA | RNRGPERTRE | SAYHIVTISH | PELDG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Glucose-dependent insulinotropic receptor
    ELISA Kit for Mouse Glucose-dependent insulinotropic receptor
    ELISA Kit for Mouse Glucose-dependent insulinotropic receptor
    CLIA Kit for Mouse Glucose-dependent insulinotropic receptor
    CLIA Kit for Mouse Glucose-dependent insulinotropic receptor
    CLIA Kit for Mouse Glucose-dependent insulinotropic receptor
    Polyclonal Antibody for Mouse Glucose-dependent insulinotropic receptor
    Polyclonal Antibody for Mouse Glucose-dependent insulinotropic receptor
    Polyclonal Antibody for Mouse Glucose-dependent insulinotropic receptor
    Monoclonal Antibody for Mouse Glucose-dependent insulinotropic receptor
    Monoclonal Antibody for Mouse Glucose-dependent insulinotropic receptor
    Monoclonal Antibody for Mouse Glucose-dependent insulinotropic receptor
    Protein for Mouse Glucose-dependent insulinotropic receptor
    Protein for Mouse Glucose-dependent insulinotropic receptor
    Protein for Mouse Glucose-dependent insulinotropic receptor

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives."
      Fredriksson R. , Hoeglund P.J. , Gloriam D.E.I. , Lagerstroem M.C. , Schioeth H.B.
      FEBS Lett.554:381-388(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Expression and distribution of Gpr119 in the pancreatic islets of mice and rats: predominant localization in pancreatic polypeptide-secreting PP-cells."
      Sakamoto Y. , Inoue H. , Kawakami S. , Miyawaki K. , Miyamoto T. , Mizuta K. , Itakura M.
      Biochem. Biophys. Res. Commun.351:474-480(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor."
      Soga T. , Ohishi T. , Matsui T. , Saito T. , Matsumoto M. , Takasaki J. , Matsumoto S. , Kamohara M. , Hiyama H. , Yoshida S. , Momose K. , Ueda Y. , Matsushime H. , Kobori M. , Furuichi K.
      Biochem. Biophys. Res. Commun.326:744-751(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    6. 6.
      "A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release."
      Chu Z.L. , Jones R.M. , He H. , Carroll C. , Gutierrez V. , Lucman A. , Moloney M. , Gao H. , Mondala H. , Bagnol D. , Unett D. , Liang Y. , Demarest K. , Semple G. , Behan D.P. , Leonard J.
      Endocrinology148:2601-2609(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
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