Protein name:
G-protein coupled receptor 124 ;
Alternative:
Tumor endothelial marker 5 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with DLG1.
Function:
Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MGAGGRRMPV | PPARLLLLPL | LPCLLLLAPG | TRGAPGCPVP | IRGCKCSGER |
100:
PKGLSGGAHN | PARRRVVCGG | GDLPEPPDPG | LLPNGTITLL | LSNNKITGLR |
150:
NGSFLGLSLL | EKLDLRSNVI | STVQPGAFLG | LGELKRLDLS | NNRIGCLTSE |
200:
TFQGLPRLLR | LNISGNIYSS | LQPGVFDELP | ALKIVDFGTE | FLTCDCRLRW |
250:
LLPWARNHSL | QLSERTLCAY | PSALHAHALS | SLQESQLRCE | GALELHTHYL |
300:
IPSLRQVVFQ | GDRLPFQCSA | SYLGNDTRIH | WYHNGAPMES | DEQAGIVLAE |
350:
NLIHDCTFIT | SELTLSHIGV | WASGEWECSV | STVQGNTSKK | VEIVVLETSA |
400:
SYCPAERVTN | NRGDFRWPRT | LAGITAYQSC | LQYPFTSVPL | SGGAPGTRAS |
450:
RRCDRAGRWE | PGDYSHCLYT | NDITRVLYTF | VLMPINASNA | LTLAHQLRVY |
500:
TAEAASFSDM | MDVVYVAQMI | QKFLGYVDQI | KELVEVMVDM | ASNLMLVDEH |
550:
LLWLAQREDK | ACSGIVGALE | RIGGAALSPH | AQHISVNSRN | VALEAYLIKP |
600:
HSYVGLTCTA | FQRREVGVSG | AQPSSVGQDA | PVEPEPLADQ | QLRFRCTTGR |
650:
PNISLSSFHI | KNSVALASIQ | LPPSLFSTLP | AALAPPVPPD | CTLQLLVFRN |
700:
GRLFRSHGNN | TSRPGAAGPG | KRRGVATPVI | FAGTSGCGVG | NLTEPVAVSL |
750:
RHWAEGADPM | AAWWNQDGPG | GWSSEGCRLR | YSQPNVSSLY | CQHLGNVAVL |
800:
MELNAFPREA | GGSGAGLHPV | VYPCTALLLL | CLFSTIITYI | LNHSSIHVSR |
850:
KGWHMLLNLC | FHMAMTSAVF | VGGVTLTNYQ | MVCQAVGITL | HYSSLSSLLW |
900:
MGVKARVLHK | ELSWRAPPLE | EGEAAPPGPR | PMLRFYLIAG | GIPLIICGIT |
950:
AAVNIHNYRD | HSPYCWLVWR | PSLGAFYIPV | ALILPITWIY | FLCAGLHLRS |
1000:
HVAQNPKQGN | RISLEPGEEL | RGSTRLRSSG | VLLNDSGSLL | ATVSAGVGTP |
1050:
APPEDGDGVY | SPGVQLGALM | TTHFLYLAMW | ACGALAVSQR | WLPRVVCSCL |
1100:
YGVAASALGL | FVFTHHCARR | RDVRASWRAC | CPPASPSASH | VPARALPTAT |
1150:
EDGSPVLGEG | PASLKSSPSG | SSGRAPPPPC | KLTNLQVAQS | QVCEASVAAR |
1200:
GDGEPEPTGS | RGSLAPRHHN | NLHHGRRVHK | SRAKGHRAGE | TGGKSRLKAL |
1250:
RAGTSPGAPE | LLSSESGSLH | NSPSDSYPGS | SRNSPGDGLP | LEGEPMLTPS |
1300:
EGSDTSAAPI | AETGRPGQRR | SASRDNLKGS | GSALERESKR | RSYPLNTTSL |
1336:
NGAPKGGKYE | DASVTGAEAI | AGGSMKTGLW | KSETTV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse G-protein coupled receptor 124
ELISA Kit for Mouse G-protein coupled receptor 124
CLIA Kit for Mouse G-protein coupled receptor 124
CLIA Kit for Mouse G-protein coupled receptor 124
Polyclonal Antibody for Mouse G-protein coupled receptor 124
Polyclonal Antibody for Mouse G-protein coupled receptor 124
Monoclonal Antibody for Mouse G-protein coupled receptor 124
Monoclonal Antibody for Mouse G-protein coupled receptor 124
Protein for Mouse G-protein coupled receptor 124
Protein for Mouse G-protein coupled receptor 124
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DEVELOPMENTAL STAGE
4.
"Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124."
Kuhnert F.
,
Mancuso M.R.
,
Shamloo A.
,
Wang H.T.
,
Choksi V.
,
Florek M.
,
Su H.
,
Fruttiger M.
,
Young W.L.
,
Heilshorn S.C.
,
Kuo C.J.
Science330:985-989(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;DISRUPTION PHENOTYPE;FUNCTION