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Index > Protein center > GPR12(Gene name) > Human
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  • GPR12 (Gene name),
  • G-protein coupled receptor 12 (Protein name ),  GPR12_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GPR12;
    Protein name:
    G-protein coupled receptor 12;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    334
    Sequence:
    50:
    MNEDLKVNLS | GLPRDYLDAA | AAENISAAVS | SRVPAVEPEP | ELVVNPWDIV | 
    100:
    LCTSGTLISC | ENAIVVLIIF | HNPSLRAPMF | LLIGSLALAD | LLAGIGLITN | 
    150:
    FVFAYLLQSE | ATKLVTIGLI | VASFSASVCS | LLAITVDRYL | SLYYALTYHS | 
    200:
    ERTVTFTYVM | LVMLWGTSIC | LGLLPVMGWN | CLRDESTCSV | VRPLTKNNAA | 
    250:
    ILSVSFLFMF | ALMLQLYIQI | CKIVMRHAHQ | IALQHHFLAT | SHYVTTRKGV | 
    300:
    STLAIILGTF | AACWMPFTLY | SLIADYTYPS | IYTYATLLPA | TYNSIINPVI | 
    334:
    YAFRNQEIQK | ALCLICCGCI | PSSLAQRARS | PSDV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    Pfam:
    MIM:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human G-protein coupled receptor 12
    ELISA Kit for Human G-protein coupled receptor 12
    ELISA Kit for Human G-protein coupled receptor 12
    CLIA Kit for Human G-protein coupled receptor 12
    CLIA Kit for Human G-protein coupled receptor 12
    CLIA Kit for Human G-protein coupled receptor 12
    Polyclonal Antibody for Human G-protein coupled receptor 12
    Polyclonal Antibody for Human G-protein coupled receptor 12
    Polyclonal Antibody for Human G-protein coupled receptor 12
    Monoclonal Antibody for Human G-protein coupled receptor 12
    Monoclonal Antibody for Human G-protein coupled receptor 12
    Monoclonal Antibody for Human G-protein coupled receptor 12
    Protein for Human G-protein coupled receptor 12
    Protein for Human G-protein coupled receptor 12
    Protein for Human G-protein coupled receptor 12

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and chromosomal localization of human genes encoding three closely related G protein-coupled receptors."
      Song Z.-H. , Modi W. , Bonner T.I.
      Genomics28:347-349(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "The DNA sequence and analysis of human chromosome 13."
      Dunham A. , Matthews L.H. , Burton J. , Ashurst J.L. , Howe K.L. , Ashcroft K.J. , Beare D.M. , Burford D.C. , Hunt S.E. , Griffiths-Jones S. , Jones M.C. , Keenan S.J. , Oliver K. , Scott C.E. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews D.T. , more...
      Nature428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain cortex.
    4. 4.
      "Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors."
      Uhlenbrock K. , Gassenhuber J. , Kostenis E.
      Cell. Signal.14:941-953(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY FUNCTION
    5. 5.
      "Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay."
      Yin H. , Chu A. , Li W. , Wang B. , Shelton F. , Otero F. , Nguyen D.G. , Caldwell J.S. , Chen Y.A.
      J. Biol. Chem.284:12328-12338(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LACK OF FUNCTION AS A SPHINGOSINE 1-PHOSPHATE RECEPTOR
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