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Index > Protein center > Gpr3(Gene name) > Rat
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  • Gpr3 (Gene name),
  • G-protein coupled receptor 3 (Protein name ),  GPR3_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Gpr3;
    Protein name:
    G-protein coupled receptor 3;
    Alternative:
    G-protein-coupled receptor R4;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavioral responses to stress (By similarity), amyloid-beta peptide generation in neurons (By similarity) and neurite outgrowth. Maintains also meiotic arrest in oocytes.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    329
    Sequence:
    50:
    MMWGAGRSMA | WFSAGSGSVN | VSIDPAEEPT | GPATLLPSPR | AWDVVLCISG | 
    100:
    TLVSCENALV | VAIIVGTPAF | RAPMFLLVGS | LAVADLLAGL | GLVLHFAADF | 
    150:
    CIGSPEMSLV | LVGVLATAFT | ASIGSLLAIT | VDRYLSLYNA | LTYYSETTVT | 
    200:
    RTYVMLALVW | VGALGLGLVP | VLAWNCRDGL | TTCGVVYPLS | KNHLVVLAIV | 
    250:
    FFMVFGIMLQ | LYAQICRIVC | RHAQQIALQR | HLLPASHYVA | TRKGIATLAV | 
    300:
    VLGAFAACWL | PFTVYCLLGD | ANSPPLYTYL | TLLPATYNSM | INPVIYAFRN | 
    329:
    QDVQKVLWAI | CCCCSTSKIP | FRSRSPSDV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat G-protein coupled receptor 3
    ELISA Kit for Rat G-protein coupled receptor 3
    ELISA Kit for Rat G-protein coupled receptor 3
    CLIA Kit for Rat G-protein coupled receptor 3
    CLIA Kit for Rat G-protein coupled receptor 3
    CLIA Kit for Rat G-protein coupled receptor 3
    Polyclonal Antibody for Rat G-protein coupled receptor 3
    Polyclonal Antibody for Rat G-protein coupled receptor 3
    Polyclonal Antibody for Rat G-protein coupled receptor 3
    Monoclonal Antibody for Rat G-protein coupled receptor 3
    Monoclonal Antibody for Rat G-protein coupled receptor 3
    Monoclonal Antibody for Rat G-protein coupled receptor 3
    Protein for Rat G-protein coupled receptor 3
    Protein for Rat G-protein coupled receptor 3
    Protein for Rat G-protein coupled receptor 3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    2. 2.
      "Isolation and chromosomal localization of a novel human G-protein-coupled receptor (GPR3) expressed predominantly in the central nervous system."
      Iismaa T.P. , Kiefer J. , Liu M.L. , Baker E. , Sutherland G.R. , Shine J.
      Genomics24:391-394(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-117
      strain: New England Deaconess Hospital.
      tissue: Pancreas.
    3. 3.
      "Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors."
      Uhlenbrock K. , Gassenhuber J. , Kostenis E.
      Cell. Signal.14:941-953(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 9-329
    4. 4.
      "Neural expression of G protein-coupled receptors GPR3, GPR6, and GPR12 up-regulates cyclic AMP levels and promotes neurite outgrowth."
      Tanaka S. , Ishii K. , Kasai K. , Yoon S.O. , Saeki Y.
      J. Biol. Chem.282:10506-10515(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
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