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Index > Protein center > GPR4(Gene name) > Human
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  • GPR4 (Gene name),
  • G-protein coupled receptor 4 (Protein name ),  GPR4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    GPR4(GPR19);
    Protein name:
    G-protein coupled receptor 4;
    Alternative:
    G-protein coupled receptor 19;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    362
    Sequence:
    50:
    MGNHTWEGCH | VDSRVDHLFP | PSLYIFVIGV | GLPTNCLALW | AAYRQVQQRN | 
    100:
    ELGVYLMNLS | IADLLYICTL | PLWVDYFLHH | DNWIHGPGSC | KLFGFIFYTN | 
    150:
    IYISIAFLCC | ISVDRYLAVA | HPLRFARLRR | VKTAVAVSSV | VWATELGANS | 
    200:
    APLFHDELFR | DRYNHTFCFE | KFPMEGWVAW | MNLYRVFVGF | LFPWALMLLS | 
    250:
    YRGILRAVRG | SVSTERQEKA | KIKRLALSLI | AIVLVCFAPY | HVLLLSRSAI | 
    300:
    YLGRPWDCGF | EERVFSAYHS | SLAFTSLNCV | ADPILYCLVN | EGARSDVAKA | 
    350:
    LHNLLRFLAS | DKPQEMANAS | LTLETPLTSK | RNSTAKAMTG | SWAATPPSQG | 
    362:
    DQVQLKMLPP | AQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    UniGene:
    SMR:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human G-protein coupled receptor 4
    ELISA Kit for Human G-protein coupled receptor 4
    ELISA Kit for Human G-protein coupled receptor 4
    ELISA Kit for Human G-protein coupled receptor 4
    ELISA Kit for Human G-protein coupled receptor 4
    CLIA Kit for Human G-protein coupled receptor 4
    CLIA Kit for Human G-protein coupled receptor 4
    CLIA Kit for Human G-protein coupled receptor 4
    CLIA Kit for Human G-protein coupled receptor 4
    CLIA Kit for Human G-protein coupled receptor 4
    Polyclonal Antibody for Human G-protein coupled receptor 4
    Polyclonal Antibody for Human G-protein coupled receptor 4
    Polyclonal Antibody for Human G-protein coupled receptor 4
    Polyclonal Antibody for Human G-protein coupled receptor 4
    Polyclonal Antibody for Human G-protein coupled receptor 4
    Monoclonal Antibody for Human G-protein coupled receptor 4
    Monoclonal Antibody for Human G-protein coupled receptor 4
    Monoclonal Antibody for Human G-protein coupled receptor 4
    Monoclonal Antibody for Human G-protein coupled receptor 4
    Monoclonal Antibody for Human G-protein coupled receptor 4
    Protein for Human G-protein coupled receptor 4
    Protein for Human G-protein coupled receptor 4
    Protein for Human G-protein coupled receptor 4
    Protein for Human G-protein coupled receptor 4
    Protein for Human G-protein coupled receptor 4

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation of three novel human genes encoding G protein-coupled receptors."
      Heiber M. , Docherty J.M. , Shah G. , Nguyen T. , Cheng R. , Heng H.H.Q. , Marchese A. , Tsui L.-C. , Shi X. , George S.R. , O'Dowd B.F.
      DNA Cell Biol.14:25-35(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Isolation of a novel G protein-coupled receptor (GPR4) localized to chromosome 19q13.3."
      Mahadevan M.S. , Baird S. , Bailly J.E. , Shutler G.G. , Sabourin L.A. , Tsilfidis C. , Neville C.E. , Narang M. , Korneluk R.G.
      Genomics30:84-88(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Cloning, sequencing and tissue distribution of two related G protein-coupled receptor candidates expressed prominently in human lung tissue."
      An S. , Tsai C. , Goetzl E.J.
      FEBS Lett.375:121-124(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      Kaighin V.A. , Martin A.L. , Aronstam R.S.
      Submitted (2007-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    6. 6.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    9. 9.
      "Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4."
      Zhu K. , Baudhuin L.M. , Hong G. , Williams F.S. , Cristina K.L. , Kabarowski J.H. , Witte O.N. , Xu Y.
      J. Biol. Chem.276:41325-41335(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY FUNCTION
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM;RETRACTION
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    12. 12.
      "Previously postulated 'ligand-independent' signaling of GPR4 is mediated through proton-sensing mechanisms."
      Tobo M. , Tomura H. , Mogi C. , Wang J.Q. , Liu J.P. , Komachi M. , Damirin A. , Kimura T. , Murata N. , Kurose H. , Sato K. , Okajima F.
      Cell. Signal.19:1745-1753(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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