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Index > Protein center > GP5(Gene name) > Human
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  • GP5 (Gene name),
  • Platelet glycoprotein V (Protein name ),  GPV_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    GP5;
    Protein name:
    Platelet glycoprotein V(GPV);
    Alternative:
    Glycoprotein 5;
    CD:
    CD42d;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    560
    Sequence:
    50:
    MLRGTLLCAV | LGLLRAQPFP | CPPACKCVFR | DAAQCSGGDV | ARISALGLPT | 
    100:
    NLTHILLFGM | GRGVLQSQSF | SGMTVLQRLM | ISDSHISAVA | PGTFSDLIKL | 
    150:
    KTLRLSRNKI | THLPGALLDK | MVLLEQLFLD | HNALRGIDQN | MFQKLVNLQE | 
    200:
    LALNQNQLDF | LPASLFTNLE | NLKLLDLSGN | NLTHLPKGLL | GAQAKLERLL | 
    250:
    LHSNRLVSLD | SGLLNSLGAL | TELQFHRNHI | RSIAPGAFDR | LPNLSSLTLS | 
    300:
    RNHLAFLPSA | LFLHSHNLTL | LTLFENPLAE | LPGVLFGEMG | GLQELWLNRT | 
    350:
    QLRTLPAAAF | RNLSRLRYLG | VTLSPRLSAL | PQGAFQGLGE | LQVLALHSNG | 
    400:
    LTALPDGLLR | GLGKLRQVSL | RRNRLRALPR | ALFRNLSSLE | SVQLDHNQLE | 
    450:
    TLPGDVFGAL | PRLTEVLLGH | NSWRCDCGLG | PFLGWLRQHL | GLVGGEEPPR | 
    500:
    CAGPGAHAGL | PLWALPGGDA | ECPGPRGPPP | RPAADSSSEA | PVHPALAPNS | 
    550:
    SEPWVWAQPV | TTGKGQDHSP | FWGFYFLLLA | VQAMITVIIV | FAMIKIGQLF | 
    560:
    RKLIRERALG | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    KEGG:
    String:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human GPV
    Cat.:
    E2240h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human GPV
    Cat.:
    E2240m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human GPV
    Cat.:
    E2240r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human GPV
    Cat.:
    U2240h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human GPV
    Cat.:
    U2240r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human GPV
    Cat.:
    U2240m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human GPV
    Cat.:
    P2240Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human GPV
    Cat.:
    P2240Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human GPV
    Cat.:
    P2240Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human GPV
    Monoclonal Antibody for Human GPV
    Monoclonal Antibody for Human GPV
    Protein for Human GPV
    Protein for Human GPV
    Protein for Human GPV

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human platelet glycoprotein V: characterization of the polypeptide and the related Ib-V-IX receptor system of adhesive, leucine-rich glycoproteins."
      Hickey M.J. , Hagen F.S. , Yagi M. , Roth G.J.
      Proc. Natl. Acad. Sci. U.S.A.90:8327-8331(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Lung.
    2. 2.
      "Cloning and characterization of the gene encoding the human platelet glycoprotein V. A member of the leucine-rich glycoprotein family cleaved during thrombin-induced platelet activation."
      Lanza F. , Morales M. , de la Salle C. , Cazenave J.-P. , Clemetson K.J. , Shimomura T. , Phillips D.R.
      J. Biol. Chem.268:20801-20807(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Platelet.
    3. 3.
      "Single novel mutation in transmembrane region of glycoprotein IX affects platelet surface expressions of glycoprotein GP-Ib-IX complex and causes Bernard Soulier syndrome."
      Xu L. , Liu L. , Zhang D. , Sun G. , Wang P. , Sun N. , Hu Q. , Li X. , Cao F. , Peng B. , Yu S.
      Submitted (2009-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Rapid purification and characterization of human platelet glycoprotein V: the amino acid sequence contains leucine-rich repetitive modules as in glycoprotein Ib."
      Shimomura T. , Fujimura K. , Maehama S. , Takemoto M. , Oda K. , Fujimoto T. , Oyama R. , Suzuki M. , Icihara-Tanaka K. , Titani K. , Kuramoto A.
      Blood75:2349-2356(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
      tissue: Platelet.
    6. 6.
      "Human platelet glycoprotein V: a surface leucine-rich glycoprotein related to adhesion."
      Roth G.J. , Church T.A. , McMullen B.A. , Williams S.A.
      Biochem. Biophys. Res. Commun.170:153-161(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
      tissue: Platelet.
    7. 7.
      "Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."
      Lewandrowski U. , Moebius J. , Walter U. , Sickmann A.
      Mol. Cell. Proteomics5:226-233(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-181
      tissue: Platelet.
    8. 8.
      "A strategy for precise and large scale identification of core fucosylated glycoproteins."
      Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
      Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-181 AND ASN-243
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