Grik3 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comGrik3 ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Grik3(Gene name) > Rat

Grik3 (Gene name),

Glutamate receptor, ionotropic kainate 3 (Protein name ), GRIK3_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Grik3(Glur7);

Protein name:

Glutamate receptor, ionotropic kainate 3(GluK3);

Alternative:

Glutamate receptor 7(GluR-7;GluR7);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homomeric GLUR7A and GLUR7B form functional kainate receptors. GLUR7A receptors have a very low sensitivity to glutamate. GLUR7A can also coassemble with either GRIK4 or GRIK5 to form heteromeric receptors. Interacts with PRKCABP. Interacts with NETO2.

Function:

Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.

Subcellular Location:

Cell membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

919

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

919:

RLPGKDSMSC | STSLAPVFP

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

Pfam:

PF01094

SMR:

P42264

UniGene:

Rn.92477

String:

P42264

KEGG:

rno:298521

Uniprot:

P42264

FOR

ELISA Kit for Rat GluK3

CLIA Kit for Rat GluK3

Polyclonal Antibody for Rat GluK3

Monoclonal Antibody for Rat GluK3

Protein for Rat GluK3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"High-affinity kainate and domoate receptors in rat brain."
Lomeli H. , Wisden W. , Koehler M. , Keinaenen K. , Sommer B. , Seeburg P.H.
FEBS Lett.307:139-143(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM GLUR7A)
tissue: Brain.
2.

Sprengel R.
Submitted (1994-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
3.

"Rat GluR7 and a carboxy-terminal splice variant, GluR7b, are functional kainate receptor subunits with a low sensitivity to glutamate."
Schiffer H.H. , Swanson G.T. , Heinemann S.F.
Neuron19:1141-1146(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM GLUR7B)
strain: Sprague-Dawley.
tissue: Brain.
4.

"Cloning of a putative glutamate receptor: a low affinity kainate-binding subunit."
Bettler B. , Egebjerg J. , Sharma G. , Pecht G. , Hermans-Borgmeyer I. , Moll C. , Stevens C.F. , Heinemann S.F.
Neuron8:257-265(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 32-919 (ISOFORM GLUR7A)
5.

"Interaction of the C-terminal tail region of the metabotropic glutamate receptor 7 with the protein kinase C substrate PICK1."
El Far O. , Airas J. , Wischmeyer E. , Nehring R.B. , Karschin A. , Betz H.
Eur. J. Neurosci.12:4215-4221(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PRKCABP
6.

"Crystal structures of the glutamate receptor ion channel GluK3 and GluK5 amino-terminal domains."
Kumar J. , Mayer M.L.
J. Mol. Biol.404:680-696(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.75 ANGSTROMS) OF 32-423;PROTEIN SEQUENCE OF N-TERMINUS;SUBUNIT;MEMBRANE TOPOLOGY;DISULFIDE BOND;GLYCOSYLATION AT ASN-70; ASN-278 AND ASN-381;IDENTIFICATION BY MASS SPECTROMETRY
7.

"Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate."
Venskutonyte R. , Frydenvang K. , Gajhede M. , Bunch L. , Pickering D.S. , Kastrup J.S.
J. Struct. Biol.176:307-314(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 432-806 IN COMPLEX WITH GLUTAMATE;FUNCTION;SUBUNIT

Product Feedback Wall

* Email:
*Comments: