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Index > Protein center > Grip1(Gene name) > Mouse
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  • Grip1 (Gene name),
  • Glutamate receptor-interacting protein 1 (Protein name ),  GRIP1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Grip1;
    Protein name:
    Glutamate receptor-interacting protein 1(GRIP-1);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with EFNB3, GRIA2, GRIA3, GRIPAP1/GRASP1, PPFIA1, PPFIA4, FRAS1, PTPRF, liprins-alpha and the C-terminal tail of PRLHR. Can form homomultimers or heteromultimers with GRIP2 (By similarity). Interacts with EFNB1, EPHA7, EPHB2, KIF5A, KIF5B and KIF5C. Forms a ternary complex with GRIA2 and CSPG4. Interacts with SLC30A9 and PLCD4.
    Function:
    May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.
    Subcellular Location:
    Isoform 2 Membrane Lipid-anchor
    Protein Attributes:
    Sequence length:
    1127
    Sequence:
    50:
    MIAVSFKCRC | QILRRLTKDE | SPYTKSASQT | KPPDGALAVR | RQSIPEEFKG | 
    100:
    STVVELMKKE | GTTLGLTVSG | GIDKDGKPRV | SNLRQGGIAA | RSDQLDVGDY | 
    150:
    IKAVNGINLA | KFRHDEIISL | LKNVGERVVL | EVEYELPPVS | VQGSSVMFRT | 
    200:
    VEVTLHKEGN | TFGFVIRGGA | HDDRNKSRPV | VITCVRPGGP | ADREGTIKPG | 
    250:
    DRLLSVDGIR | LLGTTHAEAM | SILKQCGQEA | TLLIEYDVSV | MDSVATASGP | 
    300:
    LLVEVAKTPG | ASLGVALTTS | VCCNKQVIVI | DKIKSASIAD | RCGALHVGDH | 
    350:
    ILSIDGTSME | YCTLAEATQF | LANTTDQVKL | EILPHHQTRL | ALKGPDHVKI | 
    400:
    QRSDRQHPWD | AWASNQCGVH | TNHHHNTYHP | DHCRVPALTF | PKALPPNSPP | 
    450:
    AMVPSSSPTS | MSAYSLSSLN | MGTLPRSLYS | TSPRGTMMRR | RLKKKDFKSS | 
    500:
    LSLASSTVGL | AGQVVHTETT | EVVLTADPVT | GFGIQLQGSV | FATETLSSPP | 
    550:
    LISYIEADSP | AERCGVLQIG | DRVMAINGIP | TEDSTFEEAN | QLLRDSSITS | 
    600:
    KVTLEIEFDV | AESVIPSSGT | FHVKLPKKHS | VELGITISSP | SSRKPGDPLV | 
    650:
    ISDIKKGSVA | HRTGTLELGD | KLLAIDNIRL | DNCSMEDAVQ | ILQQCEDLVK | 
    700:
    LKIRKDEDNS | DEQESSGAII | YTVELKRYGG | PLGITISGTE | EPFDPIIISS | 
    750:
    LTKGGLAERT | GAIHIGDRIL | AINSSSLKGK | PLSEAIHLLQ | MAGETVTLKI | 
    800:
    KKQTDAQSAS | SPKKFPIPGH | SGDLGDGEED | PSPIQKPGKL | SDAYPSTVPS | 
    850:
    VDSAVDSWDG | SGIDASYGSQ | GSTFQTSGYN | YNTYDWRSPK | QRTSLSPVPK | 
    900:
    PRSQTYPDVG | LSNEDWDRST | ASGFVGASDS | ADAEQEENFW | SQALEDLETC | 
    950:
    GQSGILRELE | EKADRRVSLR | NMTLLATIMS | GSTMSLNHEA | PMARSQLGRQ | 
    1000:
    ASFQERSSSR | PHYSQTTRSN | TLPSDVGRKS | VTLRKMKQEI | KEIMSPTPVE | 
    1050:
    LHKVTLYKDS | GMEDFGFSVA | DGLLEKGVYV | KNIRPAGPGD | VGGLKPYDRL | 
    1100:
    LQVNHVRTRD | FDCCLVVPLI | AESGNKLDLV | ISRNPLASQK | SIEQPALPSD | 
    1127:
    WSEQNSAFFQ | QPSHGGNLET | REPTNTL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse GRIP-1
    ELISA Kit for Mouse GRIP-1
    ELISA Kit for Mouse GRIP-1
    CLIA Kit for Mouse GRIP-1
    CLIA Kit for Mouse GRIP-1
    CLIA Kit for Mouse GRIP-1
    Polyclonal Antibody for Mouse GRIP-1
    Polyclonal Antibody for Mouse GRIP-1
    Polyclonal Antibody for Mouse GRIP-1
    Monoclonal Antibody for Mouse GRIP-1
    Monoclonal Antibody for Mouse GRIP-1
    Monoclonal Antibody for Mouse GRIP-1
    Protein for Mouse GRIP-1
    Protein for Mouse GRIP-1
    Protein for Mouse GRIP-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Differential palmitoylation of two mouse glutamate receptor interacting protein 1 forms with different N-terminal sequences."
      Yamazaki M. , Fukaya M. , Abe M. , Ikeno K. , Kakizaki T. , Watanabe M. , Sakimura K.
      Neurosci. Lett.304:81-84(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3);DEVELOPMENTAL STAGE;TISSUE SPECIFICITY;PALMITOYLATION OF ISOFORM 2
      tissue: Brain.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      strain: C57BL/6J.
      tissue: Testis.
    3. 3.
      "PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands."
      Torres R. , Firestein B.L. , Dong H. , Staudinger J. , Olson E.N. , Huganir R.L. , Bredt D.S. , Gale N.W. , Yancopoulos G.D.
      Neuron21:1453-1463(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EFNB1; EPHA7 AND EPHB2
    4. 4.
      "Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites."
      Setou M. , Seog D.-H. , Tanaka Y. , Kanai Y. , Takei Y. , Kawagishi M. , Hirokawa N.
      Nature417:83-87(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KIF5A; KIF5B AND KIF5C
    5. 5.
      "The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling."
      Stegmueller J. , Werner H. , Nave K.-A. , Trotter J.
      J. Biol. Chem.278:3590-3598(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CSPG4 AND GRIA2;DOMAIN;TISSUE SPECIFICITY
    6. 6.
      "Phospholipase Cdelta4 associates with glutamate receptor interacting protein 1 in testis."
      Irino Y. , Ichinohe M. , Nakamura Y. , Nakahara M. , Fukami K.
      J. Biochem.138:451-456(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PLCD4
    7. 7.
      "GAC63, a GRIP1-dependent nuclear receptor coactivator."
      Chen Y.-H. , Kim J.H. , Stallcup M.R.
      Mol. Cell. Biol.25:5965-5972(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SLC30A9
    8. 8.
      "The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior."
      Zhang J. , Wang Y. , Chi Z. , Keuss M.J. , Pai Y.M. , Kang H.C. , Shin J.H. , Bugayenko A. , Wang H. , Xiong Y. , Pletnikov M.V. , Mattson M.P. , Dawson T.M. , Dawson V.L.
      Cell145:284-299(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATAD1 AND GRIA2
    9. 9.
      "Solution structure of the PDZ domain from mouse glutamate receptor interacting protein 1A-L (GRIP1) homolog."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2004-05) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 461-570
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