Grip1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comGrip1 ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Grip1(Gene name) > Rat

Grip1 (Gene name),

Glutamate receptor-interacting protein 1 (Protein name ), GRIP1_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Grip1;

Protein name:

Glutamate receptor-interacting protein 1(GRIP-1);

Alternative:

AMPA receptor-interacting protein GRIP1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with EFNB1, EPHA7, EPHB2, EFNB3, KIF5A, KIF5C, KIF5B and the C-terminal tail of PRLHR. Forms a ternary complex with GRIA2 and CSPG4 (By similarity). Can form homomultimers or heteromultimers with GRIP2. Interacts with GRIA2, GRIA3, GRIPAP1/GRASP1, PPFIA1, PPFIA4, FRAS1, PLCD4, PTPRF and liprins-alpha. Interacts with SLC30A9.

Function:

May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.

Subcellular Location:

Cytoplasm Endomembrane system Peripheral membrane protein Cell junction synapse postsynaptic cell membrane Cell junction synapse postsynaptic cell membrane postsynaptic density Endoplasmic reticulum membrane Peripheral membrane protein Membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in post-synaptic plasma membrane and post-synaptic densities.

Protein Attributes:

Sequence length:

1112

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1112:

GNLETREPTN | TL

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

P97879

KEGG:

rno:84016

STRING:

10116.ENSRNOP00000061369

String:

P97879

UniGene:

Rn.74240

Pfam:

PF00595

Uniprot:

P97879

FOR

ELISA Kit for Rat GRIP-1

CLIA Kit for Rat GRIP-1

Polyclonal Antibody for Rat GRIP-1

Monoclonal Antibody for Rat GRIP-1

Protein for Rat GRIP-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors."
Dong H. , O'Brien R.J. , Fung E.T. , Lanahan A.A. , Worley P.F. , Huganir R.L.
Nature386:279-284(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH GRIA2 AND GRIA3;TISSUE SPECIFICITY;FUNCTION
tissue: Hippocampus.
2.

"A four PDZ domain-containing splice variant form of GRIP1 is localized in GABAergic and glutamatergic synapses in the brain."
Charych E.I. , Yu W. , Li R. , Serwanski D.R. , Miralles C.P. , Li X. , Yang B.Y. , Pinal N. , Walikonis R. , De Blas A.L.
J. Biol. Chem.279:38978-38990(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);SUBCELLULAR LOCATION;INTERACTION WITH GRIA2 AND GRIA3
strain: Sprague-Dawley.
tissue: Brain.
3.

"Characterization of the glutamate receptor-interacting proteins GRIP1 and GRIP2."
Dong H. , Zhang P. , Song I. , Petralia R.S. , Liao D. , Huganir R.L.
J. Neurosci.19:6930-6941(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;INTERACTION WITH GRIA2;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;SUBCELLULAR LOCATION
4.

"GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex."
Ye B. , Liao D. , Zhang X. , Zhang P. , Dong H. , Huganir R.L.
Neuron26:603-617(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GRIPAP1
5.

"Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting."
Wyszynski M. , Kim E. , Dunah A.W. , Passafaro M. , Valtschanoff J.G. , Serra-Pages C. , Streuli M. , Weinberg R.J. , Sheng M.
Neuron34:39-52(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PPFIA1; PPFIA4; PTPRF AND LIPRINS-ALPHA
6.

"Association of the AMPA receptor-related postsynaptic density proteins GRIP and ABP with subsets of glutamate-sensitive neurons in the rat retina."
Gabriel R. , de Souza S. , Ziff E.B. , Witkovsky P.
J. Comp. Neurol.449:129-140(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
7.

"The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior."
Zhang J. , Wang Y. , Chi Z. , Keuss M.J. , Pai Y.M. , Kang H.C. , Shin J.H. , Bugayenko A. , Wang H. , Xiong Y. , Pletnikov M.V. , Mattson M.P. , Dawson T.M. , Dawson V.L.
Cell145:284-299(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATAD1 AND GRIA2
8.

"PDZ7 of glutamate receptor interacting protein binds to its target via a novel hydrophobic surface area."
Feng W. , Fan J.-S. , Jiang M. , Shi Y.-W. , Zhang M.
J. Biol. Chem.277:41140-41146(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 980-1070;INTERACTION WITH GRASP1
9.

"The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling."
Stegmueller J. , Werner H. , Nave K.-A. , Trotter J.
J. Biol. Chem.278:3590-3598(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CSPG4;DOMAIN
10.

"A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1."
Takamiya K. , Kostourou V. , Adams S. , Jadeja S. , Chalepakis G. , Scambler P.J. , Huganir R.L. , Adams R.H.
Nat. Genet.36:172-177(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FRAS1

Product Feedback Wall

* Email:
*Comments: