GSTP1 ELISA Kit for Human(Homo sapiens) | EIAab.comGSTP1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > GSTP1(Gene name) > Human

GSTP1 (Gene name),

Glutathione S-transferase P (Protein name ), GSTP1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

GSTP1(FAEES3;GST3);

Protein name:

Glutathione S-transferase P;

Alternative:

GSTP1-1;GST class-pi;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer. Interacts with CDK5.

Function:

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

210

Sequence:

50:

100:

150:

200:

210:

NLPINGNGKQ |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

134660

SMR:

P09211

STRING:

9606.ENSP00000381607

String:

P09211

UniGene:

Hs.523836

KEGG:

hsa:2950

Pfam:

PF00043

Uniprot:

P09211

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ELISA Kit for Human Glutathione S-transferase P

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E1090h

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ELISA Kit for Human Glutathione S-transferase P

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E1090p

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ELISA Kit for Human Glutathione S-transferase P

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E1090r

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ELISA Kit for Human Glutathione S-transferase P

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E1090m

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96T

ELISA Kit for Human Glutathione S-transferase P

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E1090b

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96T

CLIA Kit for Human Glutathione S-transferase P

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U1090r

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96T

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CLIA Kit for Human Glutathione S-transferase P

Cat.:

U1090p

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96T

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CLIA Kit for Human Glutathione S-transferase P

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U1090h

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96T

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CLIA Kit for Human Glutathione S-transferase P

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U1090m

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96T

CLIA Kit for Human Glutathione S-transferase P

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U1090b

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96T

Polyclonal Antibody for Human Glutathione S-transferase P

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P1090Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Glutathione S-transferase P

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P1090Rb-m

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Polyclonal Antibody for Human Glutathione S-transferase P

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P1090Rb-r

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Polyclonal Antibody for Human Glutathione S-transferase P

Monoclonal Antibody for Human Glutathione S-transferase P

Protein for Human Glutathione S-transferase P

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"Structure and expression of a human class pi glutathione S-transferase messenger RNA."
Kano T. , Sakai M. , Muramatsu M.
Cancer Res.47:5626-5630(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The structure of the human glutathione S-transferase pi gene."
Cowell I.G. , Dixon K.H. , Pemble S.E. , Ketterer B. , Taylor J.B.
Biochem. J.255:79-83(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Structure of the human genomic glutathione S-transferase-pi gene."
Morrow C.S. , Cowan K.H. , Goldsmith M.E.
Gene75:3-11(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Expression of anionic glutathione-S-transferase and P-glycoprotein genes in human tissues and tumors."
Moscow J.A. , Fairchild C.R. , Madden M.J. , Ransom D.T. , Wieand H.S. , O'Brien E.E. , Poplack D.G. , Cossman J. , Myers C.E. , Cowan K.H.
Cancer Res.49:1422-1428(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
5.

"Human fatty acid ethyl ester synthase III gene: genomic organization, nucleotide sequence, genetic and chromosomal sublocalization."
Bora P.S. , Smith C. , Lange L.G. , Bora N.S. , Jones C. , Gerhard D.S.
Submitted (1994-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins."
Ali-Osman F. , Akande O. , Antoun G. , Mao J.X. , Buolamwini J.
J. Biol. Chem.272:10004-10012(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS VAL-105 AND VAL-114
7.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
8.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
9.

NIEHS SNPs program
Submitted (2003-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS VAL-105 AND VAL-114
10.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT VAL-105
tissue: Urinary bladder.
11.

"Structural evidence for three different types of glutathione transferase in human tissues."
Alin P. , Mannervik B. , Joernvall H.
FEBS Lett.182:319-322(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-24
12.

"Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties."
Mannervik B. , Alin P. , Guthenberg C. , Jensson H. , Tahir M.K. , Warholm M. , Joernvall H.
Proc. Natl. Acad. Sci. U.S.A.82:7202-7206(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-24
13.

"Purification and characterization of unique glutathione S-transferases from human muscle."
Singh S.V. , Ahmad H. , Kurosky A. , Awasthi Y.C.
Arch. Biochem. Biophys.264:13-22(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-14
14.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-12
tissue: Platelet.
15.

Lubec G. , Vishwanath V. , Chen W.-Q. , Sun Y.
Submitted (2008-12) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-12; 20-71; 76-101; 104-141; 122-141 AND 192-209;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Brain.
tissue: Cajal-Retzius cell.
tissue: Fetal brain cortex.
16.

"A two-dimensional gel database of human colon carcinoma proteins."
Ji H. , Reid G.E. , Moritz R.L. , Eddes J.S. , Burgess A.W. , Simpson R.J.
Electrophoresis18:605-613(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE
tissue: Colon carcinoma.
17.

"Primary and secondary structural analyses of glutathione S-transferase pi from human placenta."
Ahmad H. , Wilson D.E. , Fritz R.R. , Singh S.V. , Medh R.D. , Nagle G.T. , Awasthi Y.C. , Kurosky A.
Arch. Biochem. Biophys.278:398-408(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRIMARY AND SECONDARY STRUCTURAL ANALYZES
18.

"Tyrosine-7 in human class Pi glutathione S-transferase is important for lowering the pKa of the thiol group of glutathione in the enzyme-glutathione complex."
Kong K.H. , Takasu K. , Inoue H. , Takahashi K.
Biochem. Biophys. Res. Commun.184:194-197(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;MUTAGENESIS OF TYR-8
19.

"Tyrosine-7 is an essential residue for the catalytic activity of human class PI glutathione S-transferase: chemical modification and site-directed mutagenesis studies."
Kong K.H. , Nishida M. , Inoue H. , Takahashi K.
Biochem. Biophys. Res. Commun.182:1122-1129(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;MUTAGENESIS OF TYR-8
20.

"Site-directed mutagenesis study on the roles of evolutionally conserved aspartic acid residues in human glutathione S-transferase P1-1."
Kong K.-H. , Inoue H. , Takahashi K.
Protein Eng.6:93-99(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF ASP-99;CATALYTIC ACTIVITY
21.

"Glutathione S-transferase pi localizes in mitochondria and protects against oxidative stress."
Goto S. , Kawakatsu M. , Izumi S. , Urata Y. , Kageyama K. , Ihara Y. , Koji T. , Kondo T.
Free Radic. Biol. Med.46:1392-1403(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
22.

"Tyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor."
Okamura T. , Singh S. , Buolamwini J. , Haystead T. , Friedman H. , Bigner D. , Ali-Osman F.
J. Biol. Chem.284:16979-16989(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-4 AND TYR-199
23.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-128;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
24.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
25.

"Glutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activity."
Sun K.H. , Chang K.H. , Clawson S. , Ghosh S. , Mirzaei H. , Regnier F. , Shah K.
J. Neurochem.118:902-914(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CDK5
26.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
27.

"Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8-A resolution."
Reinemer P. , Dirr H.W. , Ladenstein R. , Huber R. , Lo Bello M. , Federici G. , Parker M.W.
J. Mol. Biol.227:214-226(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) COMPLEX WITH S-HEXYLGLUTATHIONE
28.

"The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate."
Oakley A.J. , Rossjohn J. , Lo Bello M. , Caccuri A.M. , Federici G. , Parker M.W.
Biochemistry36:576-585(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) IN COMPLEX WITH THE INHIBITOR ETHACRYNIC ACID AND GLUTATHIONE
29.

"Structure and function of the xenobiotic substrate-binding site and location of a potential non-substrate-binding site in a class pi glutathione S-transferase."
Ji X. , Tordova M. , O'Donnell R. , Parsons J.F. , Hayden J.B. , Gilliland G.L. , Zimniak P.
Biochemistry36:9690-9702(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) IN COMPLEXES WITH GLUTATHIONE AND INHIBITOR
30.

"The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution."
Oakley A.J. , Lo Bello M. , Battistoni A. , Ricci G. , Rossjohn J. , Villar H.O. , Parker M.W.
J. Mol. Biol.274:84-100(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) IN COMPLEXES WITH GLUTATHIONE
31.

"Structures of class pi glutathione S-transferase from human placenta in complex with substrate, transition-state analogue and inhibitor."
Prade L. , Huber R. , Manoharan T.H. , Fahl W.E. , Reuter W.
Structure5:1287-1295(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS)
32.

"Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1."
Ji X. , Blaszczyk J. , Xiao B. , O'Donnell R. , Hu X. , Herzog C. , Singh S.V. , Zimniak P.
Biochemistry38:10231-10238(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS)
33.

"Solution structure of glutathione bound to human glutathione transferase P1-1: comparison of NMR measurements with the crystal structure."
Nicotra M. , Paci M. , Sette M. , Oakley A.J. , Parker M.W. , Lo Bello M. , Caccuri A.M. , Federici G. , Ricci G.
Biochemistry37:3020-3027(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
34.

"Rational design of an organometallic glutathione transferase inhibitor."
Ang W.H. , Parker L.J. , De Luca A. , Juillerat-Jeanneret L. , Morton C.J. , Lo Bello M. , Parker M.W. , Dyson P.J.
Angew. Chem. Int. Ed.48:3854-3857(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS)
35.

"Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases."
Federici L. , Lo Sterzo C. , Pezzola S. , Di Matteo A. , Scaloni F. , Federici G. , Caccuri A.M.
Cancer Res.69:8025-8034(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.53 ANGSTROMS) OF 2-210

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