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Index > Protein center > Gtpbp1(Gene name) > Rat
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  • Gtpbp1 (Gene name),
  • GTP-binding protein 1 (Protein name ),  GTPB1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Gtpbp1(rCG_59751);
    Protein name:
    GTP-binding protein 1;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with EXOSC2/RRP4, EXOSC3/RRP40, EXOSC5/RRP46, HNRNPD, HNRNPR and SYNCRIP. Identified in a complex with HNRNPD, HNRNPL, HNRNPQ, HNRNPR, HNRNPU and AANAT mRNA, but does not bind mRNA by itself.
    Function:
    Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    669
    Sequence:
    50:
    MAAERSRSPV | DSPVPASMFA | PEPSSPGAAR | AAAAAARLHG | GFDSDCSEDG | 
    100:
    EALNGEPELD | LTSKLVLVSP | TSEQYDSLLR | QMWERMDEGC | GETIYVIGQG | 
    150:
    SDGTEYGLSE | ADMEASYATV | KSMAEQIEAD | VILLRERQES | GGRVRDYLVR | 
    200:
    KRVGDNDFLE | VRVAVVGNVD | AGKSTLLGVL | THGELDNGRG | FARQKLFRHK | 
    250:
    HEIESGRTSS | VGNDILGFDS | EGNVVNKPDS | HGGSLEWTKI | CEKSSKVITF | 
    300:
    IDLAGHEKYL | KTTVFGMTGH | LPDFCMLMVG | SNAGIVGMTK | EHLGLALALN | 
    350:
    VPVFVVVTKI | DMCPANILQE | TLKLLQRLLK | SPGCRKIPVL | VQSKDDVIVT | 
    400:
    ASNFSSERMC | PIFQISNVTG | ENLDLLKMFL | NLLSPRTSYR | EEEPAEFQID | 
    450:
    DTYSVPGVGT | VVSGTTLRGL | IKLNDTLLLG | PDPLGNFLSI | AVKSIHRKRM | 
    500:
    PVKEVRGGQT | ASFALKKIKR | SSIRKGMVMV | SPRLNPQASW | EFEAEILVLH | 
    550:
    HPTTISPRYQ | AMVHCGSIRQ | TATILSMDKD | CLRTGDKATV | HFRFIKTPEY | 
    600:
    LHIDQRLVFR | EGRTKAVGTI | TKLLQTTNNS | PMNSKPQQIK | MQSTKKGPLS | 
    650:
    KREEGGPSGV | PAAGPPSTGD | EASSLGTTQA | ATSSGLQPQP | KPSSGGRRRG | 
    669:
    GQRHKVKSQG | ACVTPASGC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat GTP-binding protein 1
    ELISA Kit for Rat GTP-binding protein 1
    ELISA Kit for Rat GTP-binding protein 1
    ELISA Kit for Rat GTP-binding protein 1
    CLIA Kit for Rat GTP-binding protein 1
    CLIA Kit for Rat GTP-binding protein 1
    CLIA Kit for Rat GTP-binding protein 1
    CLIA Kit for Rat GTP-binding protein 1
    Polyclonal Antibody for Rat GTP-binding protein 1
    Polyclonal Antibody for Rat GTP-binding protein 1
    Polyclonal Antibody for Rat GTP-binding protein 1
    Polyclonal Antibody for Rat GTP-binding protein 1
    Monoclonal Antibody for Rat GTP-binding protein 1
    Monoclonal Antibody for Rat GTP-binding protein 1
    Monoclonal Antibody for Rat GTP-binding protein 1
    Monoclonal Antibody for Rat GTP-binding protein 1
    Protein for Rat GTP-binding protein 1
    Protein for Rat GTP-binding protein 1
    Protein for Rat GTP-binding protein 1
    Protein for Rat GTP-binding protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      Kim T.-D. , Kim K.-T.
      Submitted (2009-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    3. 3.
      "Modulation of exosome-mediated mRNA turnover by interaction of GTP-binding protein 1 (GTPBP1) with its target mRNAs."
      Woo K.C. , Kim T.D. , Lee K.H. , Kim D.Y. , Kim S. , Lee H.R. , Kang H.J. , Chung S.J. , Senju S. , Nishimura Y. , Kim K.T.
      FASEB J.25:2757-2769(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH HNRNPD; HNRNPR; SYNCRIP; EXOSC2; EXOSC3 AND EXOSC5;IDENTIFICATION IN A COMPLEX WITH HNRNPD; HNRNPL; HNRNPQ; HNRNPR; HNRNPU AND MRNA;GTP BINDING;GTPASE ACTIVITY;SUBCELLULAR LOCATION;MUTAGENESIS OF LYS-173 AND 173-LYS-SER-174;TISSUE SPECIFICITY
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