Guanylyl cyclase-activating protein 3 (Protein name
), GUC1C_HUMAN from NCBI database.
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Gene name:
GUCA1C(GCAP3);
Protein name:
Guanylyl cyclase-activating protein 3(GCAP 3);
Alternative:
Guanylate cyclase activator 1C;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
N/A
Function:
Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
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Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2);CHARACTERIZATION;MYRISTOYLATION AT GLY-2;VARIANT ILE-72
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Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) IN COMPLEX WITH CALCIUM IONS