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Index > Protein center > HPX(Gene name) > Human
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  • HPX (Gene name),
  • Hemopexin (Protein name ),  HEMO_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    HPX;
    Protein name:
    Hemopexin;
    Alternative:
    Beta-1B-glycoprotein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with HEV ORF3 protein. Interacts with FLVCR1.
    Function:
    Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    462
    Sequence:
    50:
    MARVLGAPVA | LGLWSLCWSL | AIATPLPPTS | AHGNVAEGET | KPDPDVTERC | 
    100:
    SDGWSFDATT | LDDNGTMLFF | KGEFVWKSHK | WDRELISERW | KNFPSPVDAA | 
    150:
    FRQGHNSVFL | IKGDKVWVYP | PEKKEKGYPK | LLQDEFPGIP | SPLDAAVECH | 
    200:
    RGECQAEGVL | FFQGDREWFW | DLATGTMKER | SWPAVGNCSS | ALRWLGRYYC | 
    250:
    FQGNQFLRFD | PVRGEVPPRY | PRDVRDYFMP | CPGRGHGHRN | GTGHGNSTHH | 
    300:
    GPEYMRCSPH | LVLSALTSDN | HGATYAFSGT | HYWRLDTSRD | GWHSWPIAHQ | 
    350:
    WPQGPSAVDA | AFSWEEKLYL | VQGTQVYVFL | TKGGYTLVSG | YPKRLEKEVG | 
    400:
    TPHGIILDSV | DAAFICPGSS | RLHIMAGRRL | WWLDLKSGAQ | ATWTELPWPH | 
    450:
    EKVDGALCME | KSLGPNSCSA | NGPGLYLIHG | PNLYCYSDVE | KLNAAKALPQ | 
    462:
    PQNVTSLLGC | TH
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    SMR:
    Pfam:
    String:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Hemopexin
    Cat.:
    E1986h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Hemopexin
    MSDS:
    Please sign in first.
    ELISA Kit for Human Hemopexin
    Cat.:
    E1986p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Hemopexin
    MSDS:
    Please sign in first.
    ELISA Kit for Human Hemopexin
    Cat.:
    E1986r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Hemopexin
    Cat.:
    E1986b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Hemopexin
    Cat.:
    E1986m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hemopexin
    Cat.:
    U1986r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hemopexin
    Cat.:
    U1986b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hemopexin
    Cat.:
    U1986m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hemopexin
    Cat.:
    U1986p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hemopexin
    MSDS:
    Please sign in first.
    CLIA Kit for Human Hemopexin
    MSDS:
    Please sign in first.
    CLIA Kit for Human Hemopexin
    Cat.:
    U1986h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Hemopexin
    Cat.:
    P1986Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Hemopexin
    Cat.:
    P1986Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Hemopexin
    Polyclonal Antibody for Human Hemopexin
    Cat.:
    P1986Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Hemopexin
    Polyclonal Antibody for Human Hemopexin
    Polyclonal Antibody for Human Hemopexin
    Monoclonal Antibody for Human Hemopexin
    Monoclonal Antibody for Human Hemopexin
    Monoclonal Antibody for Human Hemopexin
    Monoclonal Antibody for Human Hemopexin
    Monoclonal Antibody for Human Hemopexin
    Monoclonal Antibody for Human Hemopexin
    Monoclonal Antibody for Human Hemopexin
    Protein for Human Hemopexin
    Protein for Human Hemopexin
    Protein for Human Hemopexin
    Protein for Human Hemopexin
    Protein for Human Hemopexin
    Protein for Human Hemopexin
    Protein for Human Hemopexin

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Structure of the human hemopexin gene and evidence for intron-mediated evolution."
      Altruda F. , Poli V. , Restagno G. , Silengo L.
      J. Mol. Evol.27:102-108(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary gland.
    3. 3.
      "The hemopexin gene maps to the same location as the beta-globin gene cluster on human chromosome 11."
      Law M.L. , Cai G.Y. , Hartz J.A. , Jones C. , Kao F.T.
      Genomics3:48-52(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-462
    4. 4.
      "The primary structure of human hemopexin deduced from cDNA sequence: evidence for internal, repeating homology."
      Altruda F. , Poli V. , Restagno G. , Argos P. , Cortese R. , Silengo L.
      Nucleic Acids Res.13:3841-3859(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 22-462
    5. 5.
      "Complete amino acid sequence of human hemopexin, the heme-binding protein of serum."
      Takahashi N. , Takahashi Y. , Putnam F.W.
      Proc. Natl. Acad. Sci. U.S.A.82:73-77(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF ACTIVE PROTEIN
    6. 6.
      "Amino acid sequence of the N-terminal region of human hemopexin."
      Frantikova V. , Borvak J. , Kluh I. , Moravek L.
      FEBS Lett.178:213-216(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-255
    7. 7.
      "Structure of human hemopexin: O-glycosyl and N-glycosyl sites and unusual clustering of tryptophan residues."
      Takahashi N. , Takahashi Y. , Putnam F.W.
      Proc. Natl. Acad. Sci. U.S.A.81:2021-2025(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;GLYCOSYLATION AT THR-24; ASN-64; ASN-64; ASN-187; ASN-240; ASN-246 AND ASN-453
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-187 AND ASN-453
      tissue: Bile.
    9. 9.
      "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."
      Bunkenborg J. , Pilch B.J. , Podtelejnikov A.V. , Wisniewski J.R.
      Proteomics4:454-465(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-187; ASN-240 AND ASN-246
      tissue: Plasma.
    10. 10.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-64 AND ASN-187
      tissue: Plasma.
    11. 11.
      "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry."
      Ramachandran P. , Boontheung P. , Xie Y. , Sondej M. , Wong D.T. , Loo J.A.
      J. Proteome Res.5:1493-1503(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-187 AND ASN-453
      tissue: Saliva.
    12. 12.
      "The ORF3 protein of hepatitis E virus interacts with hemopexin by means of its 26 amino acid N-terminal hydrophobic domain II."
      Ratra R. , Kar-Roy A. , Lal S.K.
      Biochemistry47:1957-1969(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HEV ORF3 PROTEIN
    13. 13.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-187 AND ASN-453
      tissue: Liver.
    14. 14.
      "A strategy for precise and large scale identification of core fucosylated glycoproteins."
      Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
      Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-187 AND ASN-453
    15. 15.
      "Enrichment of glycopeptides for glycan structure and attachment site identification."
      Nilsson J. , Rueetschi U. , Halim A. , Hesse C. , Carlsohn E. , Brinkmalm G. , Larson G.
      Nat. Methods6:809-811(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT THR-24; ASN-64; ASN-187 AND ASN-453;STRUCTURE OF CARBOHYDRATES
      tissue: Cerebrospinal fluid.
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      "Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin."
      Yang Z. , Philips J.D. , Doty R.T. , Giraudi P. , Ostrow J.D. , Tiribelli C. , Smith A. , Abkowitz J.L.
      J. Biol. Chem.285:28874-28882(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FLVCR1
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      "LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins."
      Halim A. , Ruetschi U. , Larson G. , Nilsson J.
      J. Proteome Res.12:573-584(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-29;IDENTIFICATION BY MASS SPECTROMETRY
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