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Index > Protein center > HMGB2(Gene name) > Human
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  • HMGB2 (Gene name),
  • High mobility group protein B2 (Protein name ),  HMGB2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    HMGB2(HMG2);
    Protein name:
    High mobility group protein B2;
    Alternative:
    High mobility group protein 2(HMG-2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2 (By similarity). Component of the SET complex, which also contains SET, ANP32A, APEX1 and NME1. Directly interacts with SET.
    Function:
    DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS).
    Subcellular Location:
    Nucleus Chromosome
    Protein Attributes:
    Sequence length:
    209
    Sequence:
    50:
    MGKGDPNKPR | GKMSSYAFFV | QTCREEHKKK | HPDSSVNFAE | FSKKCSERWK | 
    100:
    TMSAKEKSKF | EDMAKSDKAR | YDREMKNYVP | PKGDKKGKKK | DPNAPKRPPS | 
    150:
    AFFLFCSEHR | PKIKSEHPGL | SIGDTAKKLG | EMWSEQSAKD | KQPYEQKAAK | 
    200:
    LKEKYEKDIA | AYRAKGKSEA | GKKGPGRPTG | SKKKNEPEDE | EEEEEEEDED | 
    209:
    EEEEDEDEE
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    MIM:
    SMR:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human High mobility group protein B2
    Cat.:
    E1476r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human High mobility group protein B2
    Cat.:
    E1476h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human High mobility group protein B2
    Cat.:
    E1476p
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human High mobility group protein B2
    Cat.:
    E1476m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human High mobility group protein B2
    Cat.:
    E1476b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human High mobility group protein B2
    Cat.:
    E1476c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human High mobility group protein B2
    Cat.:
    U1476p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human High mobility group protein B2
    Cat.:
    U1476b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human High mobility group protein B2
    Cat.:
    U1476h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human High mobility group protein B2
    Cat.:
    U1476r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human High mobility group protein B2
    Cat.:
    U1476c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human High mobility group protein B2
    Cat.:
    U1476m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human High mobility group protein B2
    Polyclonal Antibody for Human High mobility group protein B2
    Cat.:
    P1476Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human High mobility group protein B2
    Polyclonal Antibody for Human High mobility group protein B2
    Cat.:
    P1476Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human High mobility group protein B2
    Cat.:
    P1476Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human High mobility group protein B2
    Monoclonal Antibody for Human High mobility group protein B2
    Monoclonal Antibody for Human High mobility group protein B2
    Monoclonal Antibody for Human High mobility group protein B2
    Monoclonal Antibody for Human High mobility group protein B2
    Monoclonal Antibody for Human High mobility group protein B2
    Monoclonal Antibody for Human High mobility group protein B2
    Protein for Human High mobility group protein B2
    Protein for Human High mobility group protein B2
    Protein for Human High mobility group protein B2
    Protein for Human High mobility group protein B2
    Protein for Human High mobility group protein B2
    Protein for Human High mobility group protein B2

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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Structure of a gene coding for human HMG2 protein."
      Shirakawa H. , Yoshida M.
      J. Biol. Chem.267:6641-6645(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2004-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Placenta.
      tissue: Skin.
    7. 7.
      "A human HMG2 cDNA with a novel 3'-untranslated region."
      Alexandre S. , Li W.W. , Lee A.S.
      Nucleic Acids Res.20:6413-6413(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 24-209
    8. 8.
      "HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A."
      Fan Z. , Beresford P.J. , Zhang D. , Lieberman J.
      Mol. Cell. Biol.22:2810-2820(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE SET COMPLEX;INTERACTION WITH SET
    9. 9.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-30;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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